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92 related items for PubMed ID: 3893787

  • 1. Potent anti-viral 5-(2-bromovinyl) uracil nucleosides are inactive at inducing gene mutations in Salmonella typhimurium and V79 Chinese hamster cells and unscheduled DNA synthesis in primary rat hepatocytes.
    Marquardt H, Westendorf J, De Clercq E, Marquardt H.
    Carcinogenesis; 1985 Aug; 6(8):1207-9. PubMed ID: 3893787
    [Abstract] [Full Text] [Related]

  • 2. Mutagenic and antimutagenic effects of 5-substituted 2'-deoxyuridines depending on the nature of the 5-substituent.
    Marquardt H, Westendorf J, Schaefer A, Boldt J, De Clercq E, Marquardt H.
    Arzneimittelforschung; 1988 Dec; 38(12):1820-4. PubMed ID: 3072958
    [Abstract] [Full Text] [Related]

  • 3. Genotoxic properties of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU).
    Oshiro Y, Piper CE, Soelter SG, Balwierz PS, Garriott ML.
    Fundam Appl Toxicol; 1992 May; 18(4):491-8. PubMed ID: 1526360
    [Abstract] [Full Text] [Related]

  • 4. Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or the Herpes simplex virus thymidine kinase.
    Grignet-Debrus C, Cool V, Baudson N, Degrève B, Balzarini J, De Leval L, Debrus S, Velu T, Calberg-Bacq CM.
    Cancer Gene Ther; 2000 Feb; 7(2):215-23. PubMed ID: 10770629
    [Abstract] [Full Text] [Related]

  • 5. Potent antiviral 2'-fluoro-arabinosyl pyrimidine nucleosides: lack of mutagenic activity.
    Marquardt H, Westendorf J, Marquardt H.
    Carcinogenesis; 1982 Feb; 3(5):593-6. PubMed ID: 7046983
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and antiviral activity of (E)-5-(2-bromovinyl)uracil and (E)-5-(2-bromovinyl)uridine.
    De Clercq E, Desgranges C, Herdewijn P, Sim IS, Jones AS, McLean MJ, Walker RT.
    J Med Chem; 1986 Feb; 29(2):213-7. PubMed ID: 3005566
    [Abstract] [Full Text] [Related]

  • 7. Structure-activity relationship of anthracycline-induced genotoxicity in vitro.
    Westendorf J, Marquardt H, Marquardt H.
    Cancer Res; 1984 Dec; 44(12 Pt 1):5599-604. PubMed ID: 6388827
    [Abstract] [Full Text] [Related]

  • 8. Analysis of toxic and mutagenic activities of antiherpesvirus nucleosides against HeLa cells and herpes simplex virus type 1.
    Suzutani T, Machida H.
    Mutat Res; 1992 May; 267(1):125-31. PubMed ID: 1373847
    [Abstract] [Full Text] [Related]

  • 9. Tumorigenicity in vivo and induction of mutagenesis and DNA repair in vitro by aclacinomycin A and marcellomycin: structure-activity relationship and predictive value of short-term tests.
    Westendorf J, Marquardt H, Ketkar MB, Mohr U, Marquardt H.
    Cancer Res; 1983 Nov; 43(11):5248-51. PubMed ID: 6352017
    [Abstract] [Full Text] [Related]

  • 10. Evaluation of propanil and its N-oxidized derivatives for genotoxicity in the Salmonella typhimurium reversion, Chinese hamster ovary/hypoxanthine guanine phosphoribosyl transferase, and rat hepatocyte/DNA repair assays.
    McMillan DC, Shaddock JG, Heflich RH, Casciano DA, Hinson JA.
    Fundam Appl Toxicol; 1988 Oct; 11(3):429-39. PubMed ID: 3065118
    [Abstract] [Full Text] [Related]

  • 11. Genotoxicity of aminohydroxynaphthoquinones in bacteria, yeast, and Chinese hamster lung fibroblast cells.
    da Costa Medina LF, Viau CM, Moura DJ, Saffi J, Stefani V, Brandelli A, Henriques JA.
    Mutat Res; 2008 Feb 29; 650(2):140-9. PubMed ID: 18178518
    [Abstract] [Full Text] [Related]

  • 12. Deoxyribosyl exchange reactions leading to the in vivo generation and regeneration of the antiviral agents (E)-5-(2-bromovinyl)-2'-deoxyuridine, 5-ethyl-2'-deoxyuridine and 5-(2-chloroethyl)-2'-deoxyuridine.
    Desgranges C, De Clercq E, Razaka G, Drouillet F, Belloc I, Bricaud H.
    Biochem Pharmacol; 1986 May 15; 35(10):1647-53. PubMed ID: 3011010
    [Abstract] [Full Text] [Related]

  • 13. DNA interaction and mutagenicity of the plastic stabilizer di-n-octyltin dichloride.
    Westendorf J, Marquardt H, Marquardt H.
    Arzneimittelforschung; 1986 Aug 15; 36(8):1263-4. PubMed ID: 3778564
    [Abstract] [Full Text] [Related]

  • 14. Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase.
    Balzarini J, Sienaert R, Liekens S, Van Kuilenburg A, Carangio A, Esnouf R, De Clercq E, McGuigan C.
    Mol Pharmacol; 2002 May 15; 61(5):1140-5. PubMed ID: 11961132
    [Abstract] [Full Text] [Related]

  • 15. Biological activity of N-nitrosodiethanolamine and of potential metabolites which may arise after activation by alcohol dehydrogenase in Salmonella typhimurium, in mammalian cells, and in vivo.
    Denkel E, Pool BL, Schlehofer JR, Eisenbrand G.
    J Cancer Res Clin Oncol; 1986 May 15; 111(2):149-53. PubMed ID: 3009488
    [Abstract] [Full Text] [Related]

  • 16. (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU).
    De Clercq E.
    Med Res Rev; 2005 Jan 15; 25(1):1-20. PubMed ID: 15389733
    [Abstract] [Full Text] [Related]

  • 17. Comparative genotoxicity studies of the flame retardant tris(2,3-dibromopropyl)phosphate and possible metabolites.
    Holme JA, Søderlund EJ, Hongslo JK, Nelson SD, Dybing E.
    Mutat Res; 1983 Dec 15; 124(3-4):213-24. PubMed ID: 6686285
    [Abstract] [Full Text] [Related]

  • 18. Mutagenicity of some N- and O-acyl derivatives of N-hydroxy-2-aminofluorene in V79 Chinese hamster cells.
    Kuroki T, Bartsch H.
    Cancer Lett; 1979 Feb 15; 6(2):67-72. PubMed ID: 373878
    [Abstract] [Full Text] [Related]

  • 19. Genotoxic activity of the N-acetylated metabolites of the food mutagens 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ).
    Brunborg G, Holme JA, Alexander J, Becher G, Hongslo JK.
    Mutagenesis; 1988 Jul 15; 3(4):303-9. PubMed ID: 3062317
    [Abstract] [Full Text] [Related]

  • 20. Genotoxicity of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): formation of 2-hydroxamino-PhIP, a directly acting genotoxic metabolite.
    Holme JA, Wallin H, Brunborg G, Søderlund EJ, Hongslo JK, Alexander J.
    Carcinogenesis; 1989 Aug 15; 10(8):1389-96. PubMed ID: 2665964
    [Abstract] [Full Text] [Related]


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