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PUBMED FOR HANDHELDS

Journal Abstract Search


116 related items for PubMed ID: 38944120

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  • 5. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y, Wang Z, Wang R, Zhang X, Zhang S, Wu Y, Staufenbiel M, Cai F, Song W.
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
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  • 6. Loss of cleavage at β'-site contributes to apparent increase in β-amyloid peptide (Aβ) secretion by β-secretase (BACE1)-glycosylphosphatidylinositol (GPI) processing of amyloid precursor protein.
    Vetrivel KS, Barman A, Chen Y, Nguyen PD, Wagner SL, Prabhakar R, Thinakaran G.
    J Biol Chem; 2011 Jul 22; 286(29):26166-77. PubMed ID: 21642424
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  • 10. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
    Sankaranarayanan S, Price EA, Wu G, Crouthamel MC, Shi XP, Tugusheva K, Tyler KX, Kahana J, Ellis J, Jin L, Steele T, Stachel S, Coburn C, Simon AJ.
    J Pharmacol Exp Ther; 2008 Mar 22; 324(3):957-69. PubMed ID: 18156464
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  • 11. Effects of BACE1 haploinsufficiency on APP processing and Aβ concentrations in male and female 5XFAD Alzheimer mice at different disease stages.
    Devi L, Ohno M.
    Neuroscience; 2015 Oct 29; 307():128-37. PubMed ID: 26314636
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  • 12. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
    Chen LM, Lin ZY, Zhu YG, Lin N, Zhang J, Pan XD, Chen XC.
    Eur J Pharmacol; 2012 Jan 30; 675(1-3):15-21. PubMed ID: 22166376
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  • 13. Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing.
    Zhao Y, Wang Y, Yang J, Wang X, Zhao Y, Zhang X, Zhang YW.
    Mol Neurodegener; 2012 Jun 18; 7():30. PubMed ID: 22709416
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  • 16. The inhibitory effects of different curcuminoids on β-amyloid protein, β-amyloid precursor protein and β-site amyloid precursor protein cleaving enzyme 1 in swAPP HEK293 cells.
    Liu H, Li Z, Qiu D, Gu Q, Lei Q, Mao L.
    Neurosci Lett; 2010 Nov 19; 485(2):83-8. PubMed ID: 20727383
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  • 19. Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.
    Chen Y, Huang X, Zhang YW, Rockenstein E, Bu G, Golde TE, Masliah E, Xu H.
    J Neurosci; 2012 Aug 15; 32(33):11390-5. PubMed ID: 22895721
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  • 20. Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis.
    Velliquette RA, O'Connor T, Vassar R.
    J Neurosci; 2005 Nov 23; 25(47):10874-83. PubMed ID: 16306400
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