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Journal Abstract Search

184 related items for PubMed ID: 39034314

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  • 3. Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
    Felszeghy S, Viiri J, Paterno JJ, Hyttinen JMT, Koskela A, Chen M, Leinonen H, Tanila H, Kivinen N, Koistinen A, Toropainen E, Amadio M, Smedowski A, Reinisalo M, Winiarczyk M, Mackiewicz J, Mutikainen M, Ruotsalainen AK, Kettunen M, Jokivarsi K, Sinha D, Kinnunen K, Petrovski G, Blasiak J, Bjørkøy G, Koskelainen A, Skottman H, Urtti A, Salminen A, Kannan R, Ferrington DA, Xu H, Levonen AL, Tavi P, Kauppinen A, Kaarniranta K.
    Redox Biol; 2019 Jan; 20():1-12. PubMed ID: 30253279
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  • 5. Repressed SIRT1/PGC-1α pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration.
    Golestaneh N, Chu Y, Cheng SK, Cao H, Poliakov E, Berinstein DM.
    J Transl Med; 2016 Dec 20; 14(1):344. PubMed ID: 27998274
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  • 8. PGC-1α repression dysregulates lipid metabolism and induces lipid droplet accumulation in retinal pigment epithelium.
    Zhou S, Taskintuna K, Hum J, Gulati J, Olaya S, Steinman J, Golestaneh N.
    Cell Death Dis; 2024 Jun 01; 15(6):385. PubMed ID: 38824126
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  • 10. Activating the AKT2-nuclear factor-κB-lipocalin-2 axis elicits an inflammatory response in age-related macular degeneration.
    Ghosh S, Shang P, Yazdankhah M, Bhutto I, Hose S, Montezuma SR, Luo T, Chattopadhyay S, Qian J, Lutty GA, Ferrington DA, Zigler JS, Sinha D.
    J Pathol; 2017 Apr 01; 241(5):583-588. PubMed ID: 28026019
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  • 11. Potential of Telomerase in Age-Related Macular Degeneration-Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α.
    Blasiak J, Szczepanska J, Fila M, Pawlowska E, Kaarniranta K.
    Int J Mol Sci; 2021 Jul 03; 22(13):. PubMed ID: 34281248
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  • 15. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
    Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi ME, Ferrari V, Vezzoli G, Tedesco B, Meroni M, Messi E, Piccolella M, Galbiati M, Garrè M, Morelli E, Vaccari T, Poletti A.
    Autophagy; 2019 Apr 03; 15(4):631-651. PubMed ID: 30335591
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  • 18. VEGF and ELAVL1/HuR protein levels are increased in dry and wet AMD patients. A new tile in the pathophysiologic mechanisms underlying RPE degeneration?
    Bresciani G, Manai F, Felszeghy S, Smedowski A, Kaarniranta K, Amadio M.
    Pharmacol Res; 2024 Oct 03; 208():107380. PubMed ID: 39216841
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  • 19. PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis.
    Kaarniranta K, Kajdanek J, Morawiec J, Pawlowska E, Blasiak J.
    Int J Mol Sci; 2018 Aug 07; 19(8):. PubMed ID: 30087287
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  • 20. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.
    Wang S, Ni HM, Chao X, Wang H, Bridges B, Kumer S, Schmitt T, Mareninova O, Gukovskaya A, De Lisle RC, Ballabio A, Pacher P, Ding WX.
    Autophagy; 2019 Nov 07; 15(11):1954-1969. PubMed ID: 30894069
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