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Journal Abstract Search

198 related items for PubMed ID: 39062759

  • 1. Synthesis and Biological Evaluation of Novel 2-Aroyl Benzofuran-Based Hydroxamic Acids as Antimicrotubule Agents.
    Mariotto E, Canton M, Marchioro C, Brancale A, Hamel E, Varani K, Vincenzi F, De Ventura T, Padroni C, Viola G, Romagnoli R.
    Int J Mol Sci; 2024 Jul 09; 25(14):. PubMed ID: 39062759
    [Abstract] [Full Text] [Related]

  • 2. Oxazole-Bridged Combretastatin A-4 Derivatives with Tethered Hydroxamic Acids: Structure⁻Activity Relations of New Inhibitors of HDAC and/or Tubulin Function.
    Schmitt F, Gosch LC, Dittmer A, Rothemund M, Mueller T, Schobert R, Biersack B, Volkamer A, Höpfner M.
    Int J Mol Sci; 2019 Jan 17; 20(2):. PubMed ID: 30658435
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological evaluation of indole-based hydroxamic acid derivatives as histone deacetylase inhibitors.
    Jiang BE, Hu J, Liu H, Liu Z, Wen Y, Liu M, Zhang HK, Pang X, Yu LF.
    Eur J Med Chem; 2022 Jan 05; 227():113893. PubMed ID: 34656899
    [Abstract] [Full Text] [Related]

  • 4. Structure-activity relationship and mechanistic studies for a series of cinnamyl hydroxamate histone deacetylase inhibitors.
    Tavares MT, de Almeida LC, Kronenberger T, Monteiro Ferreira G, Fujii de Divitiis T, Franco Zannini Junqueira Toledo M, Mariko Aymoto Hassimotto N, Agostinho Machado-Neto J, Veras Costa-Lotufo L, Parise-Filho R.
    Bioorg Med Chem; 2021 Apr 01; 35():116085. PubMed ID: 33668008
    [Abstract] [Full Text] [Related]

  • 5. Quinazoline-Based Hydroxamic Acids: Design, Synthesis, and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity.
    Hieu DT, Anh DT, Hai PT, Huong LT, Park EJ, Choi JE, Kang JS, Dung PTP, Han SB, Nam NH.
    Chem Biodivers; 2018 Jun 01; 15(6):e1800027. PubMed ID: 29667768
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors.
    Oliva P, Romagnoli R, Manfredini S, Brancale A, Ferla S, Hamel E, Ronca R, Maccarinelli F, Giacomini A, Rruga F, Mariotto E, Viola G, Bortolozzi R.
    Eur J Med Chem; 2020 Aug 15; 200():112448. PubMed ID: 32417696
    [Abstract] [Full Text] [Related]

  • 7. A hybrid of thiazolidinone with the hydroxamate scaffold for developing novel histone deacetylase inhibitors with antitumor activities.
    Yang F, Peng S, Li Y, Su L, Peng Y, Wu J, Chen H, Liu M, Yi Z, Chen Y.
    Org Biomol Chem; 2016 Feb 07; 14(5):1727-35. PubMed ID: 26732459
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of colchicine derivatives as novel tubulin and histone deacetylase dual inhibitors.
    Zhang X, Kong Y, Zhang J, Su M, Zhou Y, Zang Y, Li J, Chen Y, Fang Y, Zhang X, Lu W.
    Eur J Med Chem; 2015 May 05; 95():127-35. PubMed ID: 25805446
    [Abstract] [Full Text] [Related]

  • 9. Novel HDAC/Tubulin Dual Inhibitor: Design, Synthesis and Docking Studies of α-Phthalimido-Chalcone Hybrids as Potential Anticancer Agents with Apoptosis-Inducing Activity.
    Mourad AAE, Mourad MAE, Jones PG.
    Drug Des Devel Ther; 2020 May 05; 14():3111-3130. PubMed ID: 32848361
    [Abstract] [Full Text] [Related]

  • 10. Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma.
    Kassab SE, Mowafy S, Alserw AM, Seliem JA, El-Naggar SM, Omar NN, Awad MM.
    J Enzyme Inhib Med Chem; 2019 Dec 05; 34(1):1062-1077. PubMed ID: 31072216
    [Abstract] [Full Text] [Related]

  • 11. The discovery of colchicine-SAHA hybrids as a new class of antitumor agents.
    Zhang X, Zhang J, Tong L, Luo Y, Su M, Zang Y, Li J, Lu W, Chen Y.
    Bioorg Med Chem; 2013 Jun 01; 21(11):3240-4. PubMed ID: 23602523
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and preliminary bioactivity studies of 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors.
    Guan P, Sun F, Hou X, Wang F, Yi F, Xu W, Fang H.
    Bioorg Med Chem; 2012 Jun 15; 20(12):3865-72. PubMed ID: 22579621
    [Abstract] [Full Text] [Related]

  • 13. Novel Conjugated Quinazolinone-Based Hydroxamic Acids: Design, Synthesis and Biological Evaluation.
    Vu TK, Thanh NT, Minh NV, Linh NH, Thao NTP, Nguyen TTB, Hien DT, Chinh LV, Duc TH, Anh LD, Hai PT.
    Med Chem; 2021 Jun 15; 17(7):732-749. PubMed ID: 32310052
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and biological evaluation of novel hydroxamates and 2-aminobenzamides as potent histone deacetylase inhibitors and antitumor agents.
    Xie R, Yao Y, Tang P, Chen G, Liu X, Yun F, Cheng C, Wu X, Yuan Q.
    Eur J Med Chem; 2017 Jul 07; 134():1-12. PubMed ID: 28391133
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biological evaluation of novel shikonin-benzo[b]furan derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.
    Shao YY, Yin Y, Lian BP, Leng JF, Xia YZ, Kong LY.
    Eur J Med Chem; 2020 Mar 15; 190():112105. PubMed ID: 32035399
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis and anticancer evaluation of acridine hydroxamic acid derivatives as dual Topo and HDAC inhibitors.
    Chen J, Li D, Li W, Yin J, Zhang Y, Yuan Z, Gao C, Liu F, Jiang Y.
    Bioorg Med Chem; 2018 Aug 07; 26(14):3958-3966. PubMed ID: 29954683
    [Abstract] [Full Text] [Related]

  • 17. 1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC.
    Ojha R, Huang HL, HuangFu WC, Wu YW, Nepali K, Lai MJ, Su CJ, Sung TY, Chen YL, Pan SL, Liou JP.
    Eur J Med Chem; 2018 Apr 25; 150():667-677. PubMed ID: 29567459
    [Abstract] [Full Text] [Related]

  • 18. Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors.
    Cai J, Wei H, Hong KH, Wu X, Cao M, Zong X, Li L, Sun C, Chen J, Ji M.
    Eur J Med Chem; 2015 Apr 25; 96():1-13. PubMed ID: 25874326
    [Abstract] [Full Text] [Related]

  • 19. Design, Synthesis and Biological Evaluation of Novel Coumarin-Based Hydroxamate Derivatives as Histone Deacetylase (Hdac) Inhibitors with Antitumor Activities.
    Yang F, Zhao N, Song J, Zhu K, Jiang CS, Shan P, Zhang H.
    Molecules; 2019 Jul 15; 24(14):. PubMed ID: 31311163
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents.
    Anh DT, Hai PT, Dung DTM, Dung PTP, Huong LT, Park EJ, Jun HW, Kang JS, Kwon JH, Tung TT, Han SB, Nam NH.
    Bioorg Med Chem Lett; 2020 Nov 15; 30(22):127537. PubMed ID: 32916298
    [Abstract] [Full Text] [Related]

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