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124 related items for PubMed ID: 39098532

  • 1. The SCR-17 and SCR-18 glycans in human complement factor H enhance its regulatory function.
    Gao X, Iqbal H, Yu DQ, Gor J, Coker AR, Perkins SJ.
    J Biol Chem; 2024 Aug 02; 300(9):107624. PubMed ID: 39098532
    [Abstract] [Full Text] [Related]

  • 2. A Dimerization Site at SCR-17/18 in Factor H Clarifies a New Mechanism for Complement Regulatory Control.
    Dunne OM, Gao X, Nan R, Gor J, Adamson PJ, Gordon DL, Moulin M, Haertlein M, Forsyth VT, Perkins SJ.
    Front Immunol; 2020 Aug 02; 11():601895. PubMed ID: 33552059
    [Abstract] [Full Text] [Related]

  • 3. Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces.
    Osborne AJ, Nan R, Miller A, Bhatt JS, Gor J, Perkins SJ.
    J Biol Chem; 2018 Nov 02; 293(44):17166-17187. PubMed ID: 30217822
    [Abstract] [Full Text] [Related]

  • 4. Structural studies in solution of the recombinant N-terminal pair of short consensus/complement repeat domains of complement receptor type 2 (CR2/CD21) and interactions with its ligand C3dg.
    Guthridge JM, Rakstang JK, Young KA, Hinshelwood J, Aslam M, Robertson A, Gipson MG, Sarrias MR, Moore WT, Meagher M, Karp D, Lambris JD, Perkins SJ, Holers VM.
    Biochemistry; 2001 May 22; 40(20):5931-41. PubMed ID: 11352728
    [Abstract] [Full Text] [Related]

  • 5. The solution structure of the complement deregulator FHR5 reveals a compact dimer and provides new insights into CFHR5 nephropathy.
    Kadkhodayi-Kholghi N, Bhatt JS, Gor J, McDermott LC, Gale DP, Perkins SJ.
    J Biol Chem; 2020 Nov 27; 295(48):16342-16358. PubMed ID: 32928961
    [Abstract] [Full Text] [Related]

  • 6. Multimeric interactions between complement factor H and its C3d ligand provide new insight on complement regulation.
    Okemefuna AI, Li K, Nan R, Ormsby RJ, Sadlon T, Gordon DL, Perkins SJ.
    J Mol Biol; 2009 Aug 07; 391(1):119-35. PubMed ID: 19505474
    [Abstract] [Full Text] [Related]

  • 7. The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
    Okemefuna AI, Gilbert HE, Griggs KM, Ormsby RJ, Gordon DL, Perkins SJ.
    J Mol Biol; 2008 Jan 04; 375(1):80-101. PubMed ID: 18005991
    [Abstract] [Full Text] [Related]

  • 8. Molecular Interactions between Complement Factor H and Its Heparin and Heparan Sulfate Ligands.
    Perkins SJ, Fung KW, Khan S.
    Front Immunol; 2014 Jan 04; 5():126. PubMed ID: 24744754
    [Abstract] [Full Text] [Related]

  • 9. Interaction of uromodulin and complement factor H enhances C3b inactivation.
    Liu M, Wang Y, Wang F, Xia M, Liu Y, Chen Y, Zhao MH.
    J Cell Mol Med; 2016 Oct 04; 20(10):1821-8. PubMed ID: 27113631
    [Abstract] [Full Text] [Related]

  • 10. The partly folded back solution structure arrangement of the 30 SCR domains in human complement receptor type 1 (CR1) permits access to its C3b and C4b ligands.
    Furtado PB, Huang CY, Ihyembe D, Hammond RA, Marsh HC, Perkins SJ.
    J Mol Biol; 2008 Jan 04; 375(1):102-18. PubMed ID: 18028942
    [Abstract] [Full Text] [Related]

  • 11. Mapping the Complement Factor H-Related Protein 1 (CFHR1):C3b/C3d Interactions.
    Hannan JP, Laskowski J, Thurman JM, Hageman GS, Holers VM.
    PLoS One; 2016 Jan 04; 11(11):e0166200. PubMed ID: 27814381
    [Abstract] [Full Text] [Related]

  • 12. Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis.
    Sharma AK, Pangburn MK.
    Proc Natl Acad Sci U S A; 1996 Oct 01; 93(20):10996-1001. PubMed ID: 8855297
    [Abstract] [Full Text] [Related]

  • 13. Solution structure of the complex between CR2 SCR 1-2 and C3d of human complement: an X-ray scattering and sedimentation modelling study.
    Gilbert HE, Eaton JT, Hannan JP, Holers VM, Perkins SJ.
    J Mol Biol; 2005 Feb 25; 346(3):859-73. PubMed ID: 15713468
    [Abstract] [Full Text] [Related]

  • 14. Complement factor H binds at two independent sites to C-reactive protein in acute phase concentrations.
    Okemefuna AI, Nan R, Miller A, Gor J, Perkins SJ.
    J Biol Chem; 2010 Jan 08; 285(2):1053-65. PubMed ID: 19850925
    [Abstract] [Full Text] [Related]

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  • 16. Folded-back solution structure of monomeric factor H of human complement by synchrotron X-ray and neutron scattering, analytical ultracentrifugation and constrained molecular modelling.
    Aslam M, Perkins SJ.
    J Mol Biol; 2001 Jun 22; 309(5):1117-38. PubMed ID: 11399083
    [Abstract] [Full Text] [Related]

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  • 18. Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self-surface-selective regulation of complement activation.
    Kerr H, Wong E, Makou E, Yang Y, Marchbank K, Kavanagh D, Richards A, Herbert AP, Barlow PN.
    J Biol Chem; 2017 Aug 11; 292(32):13345-13360. PubMed ID: 28637873
    [Abstract] [Full Text] [Related]

  • 19. Cell surface expression of the C3b/C4b receptor (CR1) protects Chinese hamster ovary cells from lysis by human complement.
    Makrides SC, Scesney SM, Ford PJ, Evans KS, Carson GR, Marsh HC.
    J Biol Chem; 1992 Dec 05; 267(34):24754-61. PubMed ID: 1447213
    [Abstract] [Full Text] [Related]

  • 20. Bivalent and co-operative binding of complement factor H to heparan sulfate and heparin.
    Khan S, Nan R, Gor J, Mulloy B, Perkins SJ.
    Biochem J; 2012 Jun 15; 444(3):417-28. PubMed ID: 22471560
    [Abstract] [Full Text] [Related]

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