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368 related items for PubMed ID: 3912685
1. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity. Heikkila RE, Nicklas WJ, Vyas I, Duvoisin RC. Neurosci Lett; 1985 Dec 18; 62(3):389-94. PubMed ID: 3912685 [Abstract] [Full Text] [Related]
2. Bioactivation of MPTP: reactive metabolites and possible biochemical sequelae. Trevor AJ, Castagnoli N, Caldera P, Ramsay RR, Singer TP. Life Sci; 1987 Feb 23; 40(8):713-9. PubMed ID: 3492651 [Abstract] [Full Text] [Related]
3. 1-methyl-4-phenylpyridine is neurotoxic to the nigrostriatal dopamine pathway. Bradbury AJ, Costall B, Domeney AM, Jenner P, Kelly ME, Marsden CD, Naylor RJ. Nature; 1987 Feb 23; 319(6048):56-7. PubMed ID: 3484542 [Abstract] [Full Text] [Related]
4. MPTP, MPP+ and mitochondrial function. Nicklas WJ, Youngster SK, Kindt MV, Heikkila RE. Life Sci; 1987 Feb 23; 40(8):721-9. PubMed ID: 3100899 [Abstract] [Full Text] [Related]
5. Comparative toxicity of MPTP, MPP+ and 3,3-dimethyl-MPDP+ to dopaminergic neurons of the rat substantia nigra. Sayre LM, Arora PK, Iacofano LA, Harik SI. Eur J Pharmacol; 1986 May 13; 124(1-2):171-4. PubMed ID: 3487462 [Abstract] [Full Text] [Related]
6. Potentiation by the tetraphenylboron anion of the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its pyridinium metabolite. Heikkila RE, Hwang J, Ofori S, Geller HM, Nicklas WJ. J Neurochem; 1990 Mar 13; 54(3):743-50. PubMed ID: 2303810 [Abstract] [Full Text] [Related]
7. Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium. Vyas I, Heikkila RE, Nicklas WJ. J Neurochem; 1986 May 13; 46(5):1501-7. PubMed ID: 3485701 [Abstract] [Full Text] [Related]
8. On the mechanisms underlying 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: the effect of perinigral infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, its metabolite and their analogs in the rat. Harik SI, Schmidley JW, Iacofano LA, Blue P, Arora PK, Sayre LM. J Pharmacol Exp Ther; 1987 May 13; 241(2):669-76. PubMed ID: 2437293 [Abstract] [Full Text] [Related]
9. Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transport. Mayer RA, Kindt MV, Heikkila RE. J Neurochem; 1986 Oct 13; 47(4):1073-9. PubMed ID: 3489072 [Abstract] [Full Text] [Related]
10. Astrocytes as a primary locus for the conversion MPTP into MPP+. Brooks WJ, Jarvis MF, Wagner GC. J Neural Transm; 1989 Oct 13; 76(1):1-12. PubMed ID: 2785159 [Abstract] [Full Text] [Related]
11. Mitochondrial and metabolic toxicity of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine. Kindt MV, Heikkila RE, Nicklas WJ. J Pharmacol Exp Ther; 1987 Sep 13; 242(3):858-63. PubMed ID: 3498818 [Abstract] [Full Text] [Related]
12. Studies on the 1-methyl-4-phenyl-2,3-dihydropyridinium species 2,3-MPDP+, the monoamine oxidase catalyzed oxidation product of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Peterson LA, Caldera PS, Trevor A, Chiba K, Castagnoli N. J Med Chem; 1985 Oct 13; 28(10):1432-6. PubMed ID: 3876442 [Abstract] [Full Text] [Related]
13. Processing of MPTP by monoamine oxidases: implications for molecular toxicology. Trevor AJ, Singer TP, Ramsay RR, Castagnoli N. J Neural Transm Suppl; 1987 Oct 13; 23():73-89. PubMed ID: 3295117 [Abstract] [Full Text] [Related]
14. Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite, N-methyl-4-phenylpyridinium ion, on dopaminergic nigrostriatal neurons in the mouse. Perry TL, Yong VW, Jones K, Wall RA, Clavier RM, Foulks JG, Wright JM. Neurosci Lett; 1985 Aug 05; 58(3):321-6. PubMed ID: 3876525 [Abstract] [Full Text] [Related]
15. Neurotoxic damage to the nigrostriatal system in rats following intranigral administration of MPDP+ and MPP+. Sun CJ, Johannessen JN, Gessner W, Namura I, Singhaniyom W, Brossi A, Chiueh CC. J Neural Transm; 1988 Aug 05; 74(2):75-86. PubMed ID: 3266233 [Abstract] [Full Text] [Related]
16. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), its metabolite cyperquat (MPP+) and energy transduction in mitochondria from rat striatum and liver. Thakar JH, Hassan MN, Grimes JD. Prog Neuropsychopharmacol Biol Psychiatry; 1988 Aug 05; 12(2-3):355-62. PubMed ID: 3260387 [Abstract] [Full Text] [Related]
17. MPP+-induced increases in extracellular potassium ion activity in rat striatal slices suggest that consequences of MPP+ neurotoxicity are spread beyond dopaminergic terminals. Hollinden GE, Sanchez-Ramos JR, Sick TJ, Rosenthal M. Brain Res; 1988 Dec 20; 475(2):283-90. PubMed ID: 3265070 [Abstract] [Full Text] [Related]
18. The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety. Bradbury AJ, Costall B, Domeney AM, Testa B, Jenner PG, Marsden CD, Naylor RJ. Neurosci Lett; 1985 Oct 24; 61(1-2):121-6. PubMed ID: 2417166 [Abstract] [Full Text] [Related]
19. Mesencephalic dopamine neurons become less sensitive to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity during development in vitro. Danias P, Nicklas WJ, Ofori S, Shen J, Mytilineou C. J Neurochem; 1989 Oct 24; 53(4):1149-55. PubMed ID: 2788714 [Abstract] [Full Text] [Related]
20. Kinetics of [3H]MPP+ uptake in dopaminergic neurons of mouse: regional effects of MPTP neurotoxicity. Sershen H, Mason MF, Debler EA, Lajtha A. Eur J Pharmacol; 1986 Jul 31; 126(3):337-9. PubMed ID: 3489627 [Abstract] [Full Text] [Related] Page: [Next] [New Search]