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169 related items for PubMed ID: 39166890

  • 1. Cyclic-di-GMP induces inflammation and acute lung injury through direct binding to MD2.
    Qian C, Zhu W, Wang J, Wang Z, Tang W, Liu X, Jin B, Xu Y, Zhang Y, Liang G, Wang Y.
    Clin Transl Med; 2024 Aug; 14(8):e1744. PubMed ID: 39166890
    [Abstract] [Full Text] [Related]

  • 2. Chalcone derivatives ameliorate lipopolysaccharide-induced acute lung injury and inflammation by targeting MD2.
    Zhang YL, Zhang WX, Yan JQ, Tang YL, Jia WJ, Xu ZW, Xu MJ, Chattipakorn N, Wang Y, Feng JP, Liu ZG, Liang G.
    Acta Pharmacol Sin; 2022 Jan; 43(1):76-85. PubMed ID: 34480112
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of myeloid differentiation factor 2 by baicalein protects against acute lung injury.
    Chen H, Zhang Y, Zhang W, Liu H, Sun C, Zhang B, Bai B, Wu D, Xiao Z, Lum H, Zhou J, Chen R, Liang G.
    Phytomedicine; 2019 Oct; 63():152997. PubMed ID: 31254764
    [Abstract] [Full Text] [Related]

  • 4. Licochalcone A protects against LPS-induced inflammation and acute lung injury by directly binding with myeloid differentiation factor 2 (MD2).
    Zhu W, Wang M, Jin L, Yang B, Bai B, Mutsinze RN, Zuo W, Chattipakorn N, Huh JY, Liang G, Wang Y.
    Br J Pharmacol; 2023 Apr; 180(8):1114-1131. PubMed ID: 36480410
    [Abstract] [Full Text] [Related]

  • 5. Heme induces inflammatory injury by directly binding to the complex of myeloid differentiation protein 2 and toll-like receptor 4.
    Lin J, Lin K, Huang L, Jiang Y, Ding X, Luo W, Samorodov AV, Pavlov VN, Liang G, Qian J, Wang Y.
    Toxicol Lett; 2022 Nov 01; 370():15-23. PubMed ID: 36115635
    [Abstract] [Full Text] [Related]

  • 6. Arachidonic acid inhibits inflammatory responses by binding to myeloid differentiation factor-2 (MD2) and preventing MD2/toll-like receptor 4 signaling activation.
    Zhang Y, Chen H, Zhang W, Cai Y, Shan P, Wu D, Zhang B, Liu H, Khan ZA, Liang G.
    Biochim Biophys Acta Mol Basis Dis; 2020 May 01; 1866(5):165683. PubMed ID: 31953218
    [Abstract] [Full Text] [Related]

  • 7. MD2 mediates angiotensin II-induced cardiac inflammation and remodeling via directly binding to Ang II and activating TLR4/NF-κB signaling pathway.
    Han J, Zou C, Mei L, Zhang Y, Qian Y, You S, Pan Y, Xu Z, Bai B, Huang W, Liang G.
    Basic Res Cardiol; 2017 Jan 01; 112(1):9. PubMed ID: 28013347
    [Abstract] [Full Text] [Related]

  • 8. Protective effects of hesperetin on lipopolysaccharide-induced acute lung injury by targeting MD2.
    Ye J, Guan M, Lu Y, Zhang D, Li C, Li Y, Zhou C.
    Eur J Pharmacol; 2019 Jun 05; 852():151-158. PubMed ID: 30807747
    [Abstract] [Full Text] [Related]

  • 9. Discovery of new MD2-targeted anti-inflammatory compounds for the treatment of sepsis and acute lung injury.
    Chen G, Xiao B, Chen L, Bai B, Zhang Y, Xu Z, Fu L, Liu Z, Li X, Zhao Y, Liang G.
    Eur J Med Chem; 2017 Oct 20; 139():726-740. PubMed ID: 28858767
    [Abstract] [Full Text] [Related]

  • 10. Shikonin inhibits myeloid differentiation protein 2 to prevent LPS-induced acute lung injury.
    Zhang Y, Xu T, Pan Z, Ge X, Sun C, Lu C, Chen H, Xiao Z, Zhang B, Dai Y, Liang G.
    Br J Pharmacol; 2018 Mar 20; 175(5):840-854. PubMed ID: 29243243
    [Abstract] [Full Text] [Related]

  • 11. Myeloid Differentiation Protein 2 Mediates Angiotensin II-Induced Liver Inflammation and Fibrosis in Mice.
    Zhang Y, Liu H, Jia W, Qi J, Zhang W, Zhang W, Liang G, Zhang Y, Chen AH.
    Molecules; 2019 Dec 19; 25(1):. PubMed ID: 31861702
    [Abstract] [Full Text] [Related]

  • 12. MD2 activation by direct AGE interaction drives inflammatory diabetic cardiomyopathy.
    Wang Y, Luo W, Han J, Khan ZA, Fang Q, Jin Y, Chen X, Zhang Y, Wang M, Qian J, Huang W, Lum H, Wu G, Liang G.
    Nat Commun; 2020 May 01; 11(1):2148. PubMed ID: 32358497
    [Abstract] [Full Text] [Related]

  • 13. Angiotensin II induces kidney inflammatory injury and fibrosis through binding to myeloid differentiation protein-2 (MD2).
    Xu Z, Li W, Han J, Zou C, Huang W, Yu W, Shan X, Lum H, Li X, Liang G.
    Sci Rep; 2017 Mar 21; 7():44911. PubMed ID: 28322341
    [Abstract] [Full Text] [Related]

  • 14. Discovery of caffeic acid phenethyl ester derivatives as novel myeloid differentiation protein 2 inhibitors for treatment of acute lung injury.
    Chen L, Jin Y, Chen H, Sun C, Fu W, Zheng L, Lu M, Chen P, Chen G, Zhang Y, Liu Z, Wang Y, Song Z, Liang G.
    Eur J Med Chem; 2018 Jan 01; 143():361-375. PubMed ID: 29202400
    [Abstract] [Full Text] [Related]

  • 15. Macrophage-derived myeloid differentiation protein 2 plays an essential role in ox-LDL-induced inflammation and atherosclerosis.
    Chen T, Huang W, Qian J, Luo W, Shan P, Cai Y, Lin K, Wu G, Liang G.
    EBioMedicine; 2020 Mar 01; 53():102706. PubMed ID: 32151799
    [Abstract] [Full Text] [Related]

  • 16. Radix Glycyrrhizae extract and licochalcone a exert an anti-inflammatory action by direct suppression of toll like receptor 4.
    Cai M, Xu YC, Deng B, Chen JB, Chen TF, Zeng KF, Chen S, Deng SH, Tan ZB, Ding WJ, Zhang SW, Liu B, Zhang JZ.
    J Ethnopharmacol; 2023 Feb 10; 302(Pt A):115869. PubMed ID: 36309116
    [Abstract] [Full Text] [Related]

  • 17. Sulforaphane inhibits the engagement of LPS with TLR4/MD2 complex by preferential binding to Cys133 in MD2.
    Koo JE, Park ZY, Kim ND, Lee JY.
    Biochem Biophys Res Commun; 2013 May 10; 434(3):600-5. PubMed ID: 23583403
    [Abstract] [Full Text] [Related]

  • 18. Piperlongumine mitigates LPS-induced inflammation and lung injury via targeting MD2/TLR4.
    Tang Y, Zhang W, Wu L, Bai B, Zheng B, Li M, Tang Y, Zhu X, Zhang Y, Wang Y, Zhang B.
    Biochem Biophys Res Commun; 2023 Jan 29; 642():118-127. PubMed ID: 36566563
    [Abstract] [Full Text] [Related]

  • 19. Myeloid differentiation protein 2 induced retinal ischemia reperfusion injury via upregulation of ROS through a TLR4-NOX4 pathway.
    Chen H, Song Z, Ying S, Yang X, Wu W, Tan Q, Ju X, Wu W, Zhang X, Qu J, Wang Y.
    Toxicol Lett; 2018 Jan 05; 282():109-120. PubMed ID: 29111459
    [Abstract] [Full Text] [Related]

  • 20. Suppression of Toll-like receptor 4 activation by caffeic acid phenethyl ester is mediated by interference of LPS binding to MD2.
    Kim SY, Koo JE, Seo YJ, Tyagi N, Jeong E, Choi J, Lim KM, Park ZY, Lee JY.
    Br J Pharmacol; 2013 Apr 05; 168(8):1933-45. PubMed ID: 23231684
    [Abstract] [Full Text] [Related]

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