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Journal Abstract Search

130 related items for PubMed ID: 39182704

  • 1. Novel detoxifier of spironolactone against triptolide-induced hepatotoxicity through inhibition of RPB1 degradation.
    Qiang L, Lee SH, Xiao P, Chunhui L, Lei G, Shaoli C, Tingjie Y, Guangli D, Wei X, Guofu Z.
    J Ethnopharmacol; 2025 Jan 10; 336():118722. PubMed ID: 39182704
    [Abstract] [Full Text] [Related]

  • 2. Activation of the farnesoid X receptor attenuates triptolide-induced liver toxicity.
    Jin J, Sun X, Zhao Z, Wang W, Qiu Y, Fu X, Huang M, Huang Z.
    Phytomedicine; 2015 Sep 15; 22(10):894-901. PubMed ID: 26321738
    [Abstract] [Full Text] [Related]

  • 3. Caspase 3 is involved in the apoptosis induced by triptolide in HK-2 cells.
    Shu B, Duan W, Yao J, Huang J, Jiang Z, Zhang L.
    Toxicol In Vitro; 2009 Jun 15; 23(4):598-602. PubMed ID: 19233258
    [Abstract] [Full Text] [Related]

  • 4. Licorice root extract and magnesium isoglycyrrhizinate protect against triptolide-induced hepatotoxicity via up-regulation of the Nrf2 pathway.
    Tan QY, Hu Q, Zhu SN, Jia LL, Xiao J, Su HZ, Huang SY, Zhang J, Jin J.
    Drug Deliv; 2018 Nov 15; 25(1):1213-1223. PubMed ID: 29791258
    [Abstract] [Full Text] [Related]

  • 5. Circadian clock regulates hepatotoxicity of Tripterygium wilfordii through modulation of metabolism.
    Zhao H, Tong Y, Lu D, Wu B.
    J Pharm Pharmacol; 2020 Dec 15; 72(12):1854-1864. PubMed ID: 32478421
    [Abstract] [Full Text] [Related]

  • 6. Compatibility with Panax notoginseng and Rehmannia glutinosa Alleviates the Hepatotoxicity and Nephrotoxicity of Tripterygium wilfordii via Modulating the Pharmacokinetics of Triptolide.
    Zhang Q, Li Y, Liu M, Duan J, Zhou X, Zhu H.
    Int J Mol Sci; 2018 Jan 19; 19(1):. PubMed ID: 29351251
    [Abstract] [Full Text] [Related]

  • 7. CYP450s-Activity Relations of Celastrol to Interact with Triptolide Reveal the Reasons of Hepatotoxicity of Tripterygium wilfordii.
    Jin C, Wu Z, Wang L, Kanai Y, He X.
    Molecules; 2019 Jun 08; 24(11):. PubMed ID: 31181731
    [Abstract] [Full Text] [Related]

  • 8. Role of MicroRNA-155 in Triptolide-induced hepatotoxicity via the Nrf2-Dependent pathway.
    Li Y, Guo L, Hou Z, Gong H, Yan M, Zhang B.
    J Ethnopharmacol; 2021 Dec 05; 281():114489. PubMed ID: 34363931
    [Abstract] [Full Text] [Related]

  • 9. Triptolide-induced hepatotoxicity can be alleviated when combined with Panax notoginseng saponins and Catapol.
    Zhou L, Zhou C, Feng Z, Liu Z, Zhu H, Zhou X.
    J Ethnopharmacol; 2018 Mar 25; 214():232-239. PubMed ID: 29277608
    [Abstract] [Full Text] [Related]

  • 10. Protective effects of silymarin on triptolide-induced acute hepatotoxicity in rats.
    Wang L, Huang QH, Li YX, Huang YF, Xie JH, Xu LQ, Dou YX, Su ZR, Zeng HF, Chen JN.
    Mol Med Rep; 2018 Jan 25; 17(1):789-800. PubMed ID: 29115625
    [Abstract] [Full Text] [Related]

  • 11. Catalpol coordinately regulates phase I and II detoxification enzymes of Triptolide through CAR and NRF2 pathways to reduce Triptolide-induced hepatotoxicity.
    Fu L, Zhou L, Geng S, Li M, Lu W, Lu Y, Feng Z, Zhou X.
    Biomed Pharmacother; 2020 Sep 25; 129():110379. PubMed ID: 32563148
    [Abstract] [Full Text] [Related]

  • 12. Protective Effect of Vitamin C on Triptolide-induced Acute Hepatotoxicity in Mice through mitigation of oxidative stress.
    Xu P, Li Y, Yu Z, Yang L, Shang R, Yan Z.
    An Acad Bras Cienc; 2019 Jun 19; 91(2):e20181257. PubMed ID: 31241707
    [Abstract] [Full Text] [Related]

  • 13. Metabolic alterations in triptolide-induced acute hepatotoxicity.
    Zhao J, Xie C, Mu X, Krausz KW, Patel DP, Shi X, Gao X, Wang Q, Gonzalez FJ.
    Biomed Chromatogr; 2018 Oct 19; 32(10):e4299. PubMed ID: 29799631
    [Abstract] [Full Text] [Related]

  • 14. Activation of Nrf2 protects against triptolide-induced hepatotoxicity.
    Li J, Shen F, Guan C, Wang W, Sun X, Fu X, Huang M, Jin J, Huang Z.
    PLoS One; 2014 Oct 19; 9(7):e100685. PubMed ID: 24988078
    [Abstract] [Full Text] [Related]

  • 15. Integrated targeted sphingolipidomics and transcriptomics reveal abnormal sphingolipid metabolism as a novel mechanism of the hepatotoxicity and nephrotoxicity of triptolide.
    Qu L, Qu F, Jia Z, Wang C, Wu C, Zhang J.
    J Ethnopharmacol; 2015 Jul 21; 170():28-38. PubMed ID: 25978956
    [Abstract] [Full Text] [Related]

  • 16. Autophagy in Triptolide-Mediated Cytotoxicity in Hepatic Cells.
    Wei YM, Luan ZH, Liu BW, Wang YH, Chang YX, Xue HQ, Ren JH.
    Int J Toxicol; 2019 Jul 21; 38(5):436-444. PubMed ID: 31342801
    [Abstract] [Full Text] [Related]

  • 17. Triptolide and atorvastatin synergistically promote hepatotoxicity in cultured hepatocytes and female Sprague-Dawley rats by inhibiting pregnane X receptor-mediated transcriptional activation of CYP3A4.
    Zheng N, Wei A, Wu T, Long L, Yang H, Li H, Wang L.
    Toxicol Lett; 2021 May 15; 342():85-94. PubMed ID: 33600922
    [Abstract] [Full Text] [Related]

  • 18. Proteasome activity inhibition mediates endoplasmic reticulum stress-apoptosis in triptolide/lipopolysaccharide-induced hepatotoxicity.
    Cheng R, Jiang Y, Zhang Y, Ismail M, Zhang L, Jiang Z, Yu Q.
    Cell Biol Toxicol; 2024 Jul 29; 40(1):60. PubMed ID: 39073694
    [Abstract] [Full Text] [Related]

  • 19. Involvement of mitochondrial pathway in triptolide-induced cytotoxicity in human normal liver L-02 cells.
    Yao J, Jiang Z, Duan W, Huang J, Zhang L, Hu L, He L, Li F, Xiao Y, Shu B, Liu C.
    Biol Pharm Bull; 2008 Apr 29; 31(4):592-7. PubMed ID: 18379047
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice.
    Kong LL, Zhuang XM, Yang HY, Yuan M, Xu L, Li H.
    Sci Rep; 2015 Jul 02; 5():11747. PubMed ID: 26134275
    [Abstract] [Full Text] [Related]

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