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Journal Abstract Search

140 related items for PubMed ID: 39216841

  • 1. VEGF and ELAVL1/HuR protein levels are increased in dry and wet AMD patients. A new tile in the pathophysiologic mechanisms underlying RPE degeneration?
    Bresciani G, Manai F, Felszeghy S, Smedowski A, Kaarniranta K, Amadio M.
    Pharmacol Res; 2024 Oct; 208():107380. PubMed ID: 39216841
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  • 2. Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
    Felszeghy S, Viiri J, Paterno JJ, Hyttinen JMT, Koskela A, Chen M, Leinonen H, Tanila H, Kivinen N, Koistinen A, Toropainen E, Amadio M, Smedowski A, Reinisalo M, Winiarczyk M, Mackiewicz J, Mutikainen M, Ruotsalainen AK, Kettunen M, Jokivarsi K, Sinha D, Kinnunen K, Petrovski G, Blasiak J, Bjørkøy G, Koskelainen A, Skottman H, Urtti A, Salminen A, Kannan R, Ferrington DA, Xu H, Levonen AL, Tavi P, Kauppinen A, Kaarniranta K.
    Redox Biol; 2019 Jan; 20():1-12. PubMed ID: 30253279
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  • 3. Potential of Telomerase in Age-Related Macular Degeneration-Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α.
    Blasiak J, Szczepanska J, Fila M, Pawlowska E, Kaarniranta K.
    Int J Mol Sci; 2021 Jul 03; 22(13):. PubMed ID: 34281248
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  • 6. PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis.
    Kaarniranta K, Kajdanek J, Morawiec J, Pawlowska E, Blasiak J.
    Int J Mol Sci; 2018 Aug 07; 19(8):. PubMed ID: 30087287
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  • 8. Mitochondrial damage and clearance in retinal pigment epithelial cells.
    Gurubaran IS.
    Acta Ophthalmol; 2024 Mar 07; 102 Suppl 282():3-53. PubMed ID: 38467968
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  • 9. Regulation of oxidative stress and inflammatory responses in human retinal pigment epithelial cells.
    Harju N.
    Acta Ophthalmol; 2022 Nov 07; 100 Suppl 273():3-59. PubMed ID: 36343937
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  • 12. Pathologic vs. protective roles of hypoxia-inducible factor 1 in RPE and photoreceptors in wet vs. dry age-related macular degeneration.
    Babapoor-Farrokhran S, Qin Y, Flores-Bellver M, Niu Y, Bhutto IA, Aparicio-Domingo S, Guo C, Rodrigues M, Domashevich T, Deshpande M, Megarity H, Chopde R, Eberhart CG, Canto-Soler V, Montaner S, Sodhi A.
    Proc Natl Acad Sci U S A; 2023 Dec 12; 120(50):e2302845120. PubMed ID: 38055741
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  • 13. Retinal pigment epithelium-specific ablation of GPx4 in adult mice recapitulates key features of geographic atrophy in age-related macular degeneration.
    Azuma K, Suzuki T, Kobayashi K, Nagahara M, Imai H, Suga A, Iwata T, Shiraya T, Aihara M, Ueta T.
    Cell Death Dis; 2024 Oct 19; 15(10):763. PubMed ID: 39426958
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  • 14. Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration.
    Ferrington DA, Ebeling MC, Kapphahn RJ, Terluk MR, Fisher CR, Polanco JR, Roehrich H, Leary MM, Geng Z, Dutton JR, Montezuma SR.
    Redox Biol; 2017 Oct 19; 13():255-265. PubMed ID: 28600982
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  • 16. PGC-1α regulates the interplay between oxidative stress, senescence and autophagy in the ageing retina important in age-related macular degeneration.
    Gurubaran IS, Watala C, Kostanek J, Szczepanska J, Pawlowska E, Kaarniranta K, Blasiak J.
    J Cell Mol Med; 2024 Apr 19; 28(8):e18051. PubMed ID: 38571282
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  • 17. Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the NFE2L2/PGC-1α-/- Mouse Model.
    Sridevi Gurubaran I, Viiri J, Koskela A, Hyttinen JMT, Paterno JJ, Kis G, Antal M, Urtti A, Kauppinen A, Felszeghy S, Kaarniranta K.
    Int J Mol Sci; 2020 Mar 13; 21(6):. PubMed ID: 32183173
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  • 19. REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2.
    Huang S, Liu CH, Wang Z, Fu Z, Britton WR, Blomfield AK, Kamenecka TM, Dunaief JL, Solt LA, Chen J.
    Redox Biol; 2022 May 13; 51():102261. PubMed ID: 35176707
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  • 20. Inducible RPE-specific GPX4 knockout causes oxidative stress and retinal degeneration with features of age-related macular degeneration.
    Wojciechowski AM, Bell BA, Song Y, Anderson BD, Conomikes A, Petruconis C, Dunaief JL.
    Exp Eye Res; 2024 Oct 13; 247():110028. PubMed ID: 39128667
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