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121 related items for PubMed ID: 39349109

  • 1. A high throughput screening assay for human Thyroperoxidase inhibitors.
    Dong H, Friedman KP, Filiatreault A, Thomson EM, Wade MG.
    Toxicol In Vitro; 2024 Dec; 101():105946. PubMed ID: 39349109
    [Abstract] [Full Text] [Related]

  • 2. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.
    Paul Friedman K, Watt ED, Hornung MW, Hedge JM, Judson RS, Crofton KM, Houck KA, Simmons SO.
    Toxicol Sci; 2016 May; 151(1):160-80. PubMed ID: 26884060
    [Abstract] [Full Text] [Related]

  • 3. Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat.
    Paul KB, Hedge JM, Macherla C, Filer DL, Burgess E, Simmons SO, Crofton KM, Hornung MW.
    Toxicology; 2013 Oct 04; 312():97-107. PubMed ID: 23959146
    [Abstract] [Full Text] [Related]

  • 4. Development of a thyroperoxidase inhibition assay for high-throughput screening.
    Paul KB, Hedge JM, Rotroff DM, Hornung MW, Crofton KM, Simmons SO.
    Chem Res Toxicol; 2014 Mar 17; 27(3):387-99. PubMed ID: 24383450
    [Abstract] [Full Text] [Related]

  • 5. A rapid assay of human thyroid peroxidase activity.
    Dong H, Godlewska M, Wade MG.
    Toxicol In Vitro; 2020 Feb 17; 62():104662. PubMed ID: 31629072
    [Abstract] [Full Text] [Related]

  • 6. In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods.
    Liu R, Novák J, Hilscherová K.
    Arch Toxicol; 2024 Aug 17; 98(8):2631-2645. PubMed ID: 38796608
    [Abstract] [Full Text] [Related]

  • 7. Extrapolating In Vitro Screening Assay Data for Thyroperoxidase Inhibition to Predict Serum Thyroid Hormones in the Rat.
    Hassan I, El-Masri H, Ford J, Brennan A, Handa S, Paul Friedman K, Gilbert ME.
    Toxicol Sci; 2020 Feb 01; 173(2):280-292. PubMed ID: 31697382
    [Abstract] [Full Text] [Related]

  • 8. Simple and rapid in vitro assay for detecting human thyroid peroxidase disruption.
    Jomaa B, de Haan LH, Peijnenburg AA, Bovee TF, Aarts JM, Rietjens IM.
    ALTEX; 2015 Feb 01; 32(3):191-200. PubMed ID: 25822105
    [Abstract] [Full Text] [Related]

  • 9. A comparison of potency differences among thyroid peroxidase (TPO) inhibitors to induce developmental toxicity and other thyroid gland-linked toxicities in humans and rats.
    Motonaga K, Ota M, Odawara K, Saito S, Welsch F.
    Regul Toxicol Pharmacol; 2016 Oct 01; 80():283-90. PubMed ID: 27350053
    [Abstract] [Full Text] [Related]

  • 10. In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase.
    Olker JH, Korte JJ, Denny JS, Haselman JT, Hartig PC, Cardon MC, Hornung MW, Degitz SJ.
    Toxicol In Vitro; 2021 Mar 01; 71():105073. PubMed ID: 33352258
    [Abstract] [Full Text] [Related]

  • 11. Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling.
    Leonard JA, Tan YM, Gilbert M, Isaacs K, El-Masri H.
    Toxicol Sci; 2016 May 01; 151(1):57-70. PubMed ID: 26865668
    [Abstract] [Full Text] [Related]

  • 12. An assay for screening xenobiotics for inhibition of rat thyroid gland peroxidase activity.
    Price RJ, Burch R, Chatham LR, Higgins LG, Currie RA, Lake BG.
    Xenobiotica; 2020 Mar 01; 50(3):318-322. PubMed ID: 31180273
    [Abstract] [Full Text] [Related]

  • 13. Recombinant human thyroid peroxidase produced in insect cells has similar properties to native human thyroid peroxidase.
    Gut P, Grennan Jones F, Sullivan A, Ziemnicka K, Smith S, Jaskólski D, Furmaniak J, Rees Smith B.
    Thyroid; 2000 Jul 01; 10(7):543-50. PubMed ID: 10958306
    [Abstract] [Full Text] [Related]

  • 14. The ultraviolet filter benzophenone 2 interferes with the thyroid hormone axis in rats and is a potent in vitro inhibitor of human recombinant thyroid peroxidase.
    Schmutzler C, Bacinski A, Gotthardt I, Huhne K, Ambrugger P, Klammer H, Schlecht C, Hoang-Vu C, Grüters A, Wuttke W, Jarry H, Köhrle J.
    Endocrinology; 2007 Jun 01; 148(6):2835-44. PubMed ID: 17379648
    [Abstract] [Full Text] [Related]

  • 15. Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases.
    Olker JH, Korte JJ, Denny JS, Hartig PC, Cardon MC, Knutsen CN, Kent PM, Christensen JP, Degitz SJ, Hornung MW.
    Toxicol Sci; 2019 Apr 01; 168(2):430-442. PubMed ID: 30561685
    [Abstract] [Full Text] [Related]

  • 16. High-Throughput Screening of ToxCast PFAS Chemical Library for Potential Inhibitors of the Human Sodium Iodide Symporter.
    Stoker TE, Wang J, Murr AS, Bailey JR, Buckalew AR.
    Chem Res Toxicol; 2023 Mar 20; 36(3):380-389. PubMed ID: 36821091
    [Abstract] [Full Text] [Related]

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  • 18. Comparison of in vitro and in vivo bioassays to measure thyroid hormone disrupting activity in water extracts.
    Leusch FDL, Aneck-Hahn NH, Cavanagh JE, Du Pasquier D, Hamers T, Hebert A, Neale PA, Scheurer M, Simmons SO, Schriks M.
    Chemosphere; 2018 Jan 20; 191():868-875. PubMed ID: 29107228
    [Abstract] [Full Text] [Related]

  • 19. Perinatal exposure to the thyroperoxidase inhibitors methimazole and amitrole perturbs thyroid hormone system signaling and alters motor activity in rat offspring.
    Ramhøj L, Svingen T, Frädrich C, Rijntjes E, Wirth EK, Pedersen K, Köhrle J, Axelstad M.
    Toxicol Lett; 2022 Jan 01; 354():44-55. PubMed ID: 34757178
    [Abstract] [Full Text] [Related]

  • 20. Testing for heterotopia formation in rats after developmental exposure to selected in vitro inhibitors of thyroperoxidase.
    Ramhøj L, Frädrich C, Svingen T, Scholze M, Wirth EK, Rijntjes E, Köhrle J, Kortenkamp A, Axelstad M.
    Environ Pollut; 2021 Aug 15; 283():117135. PubMed ID: 33892370
    [Abstract] [Full Text] [Related]

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