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125 related items for PubMed ID: 39383227

  • 1. The pro-apoptotic function of the C. elegans BCL-2 homolog CED-9 requires interaction with the APAF-1 homolog CED-4.
    Tucker N, Reddien P, Hersh B, Lee D, Liu MHX, Horvitz HR.
    Sci Adv; 2024 Oct 11; 10(41):eadn0325. PubMed ID: 39383227
    [Abstract] [Full Text] [Related]

  • 2. Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization is not consistent with the current model for C. elegans apoptosis induction.
    Pourkarimi E, Greiss S, Gartner A.
    Cell Death Differ; 2012 Mar 11; 19(3):406-15. PubMed ID: 21886181
    [Abstract] [Full Text] [Related]

  • 3. Both the caspase CSP-1 and a caspase-independent pathway promote programmed cell death in parallel to the canonical pathway for apoptosis in Caenorhabditis elegans.
    Denning DP, Hatch V, Horvitz HR.
    PLoS Genet; 2013 Mar 11; 9(3):e1003341. PubMed ID: 23505386
    [Abstract] [Full Text] [Related]

  • 4. Cap-independent translation promotes C. elegans germ cell apoptosis through Apaf-1/CED-4 in a caspase-dependent mechanism.
    Contreras V, Friday AJ, Morrison JK, Hao E, Keiper BD.
    PLoS One; 2011 Mar 11; 6(9):e24444. PubMed ID: 21909434
    [Abstract] [Full Text] [Related]

  • 5. Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation.
    Hu Y, Benedict MA, Wu D, Inohara N, Núñez G.
    Proc Natl Acad Sci U S A; 1998 Apr 14; 95(8):4386-91. PubMed ID: 9539746
    [Abstract] [Full Text] [Related]

  • 6. The core apoptotic executioner proteins CED-3 and CED-4 promote initiation of neuronal regeneration in Caenorhabditis elegans.
    Pinan-Lucarre B, Gabel CV, Reina CP, Hulme SE, Shevkoplyas SS, Slone RD, Xue J, Qiao Y, Weisberg S, Roodhouse K, Sun L, Whitesides GM, Samuel A, Driscoll M.
    PLoS Biol; 2012 Apr 14; 10(5):e1001331. PubMed ID: 22629231
    [Abstract] [Full Text] [Related]

  • 7. Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1.
    Jabbour AM, Puryer MA, Yu JY, Lithgow T, Riffkin CD, Ashley DM, Vaux DL, Ekert PG, Hawkins CJ.
    J Cell Sci; 2006 Jun 15; 119(Pt 12):2572-82. PubMed ID: 16735440
    [Abstract] [Full Text] [Related]

  • 8. The cisd gene family regulates physiological germline apoptosis through ced-13 and the canonical cell death pathway in Caenorhabditis elegans.
    King SD, Gray CF, Song L, Nechushtai R, Gumienny TL, Mittler R, Padilla PA.
    Cell Death Differ; 2019 Jan 15; 26(1):162-178. PubMed ID: 29666474
    [Abstract] [Full Text] [Related]

  • 9. Apoptosome assembly.
    Shi Y.
    Methods Enzymol; 2008 Jan 15; 442():141-56. PubMed ID: 18662568
    [Abstract] [Full Text] [Related]

  • 10. DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans.
    Jagasia R, Grote P, Westermann B, Conradt B.
    Nature; 2005 Feb 17; 433(7027):754-60. PubMed ID: 15716954
    [Abstract] [Full Text] [Related]

  • 11. Failure of Bcl-2 family members to interact with Apaf-1 in normal and apoptotic cells.
    Conus S, Rossé T, Borner C.
    Cell Death Differ; 2000 Oct 17; 7(10):947-54. PubMed ID: 11279541
    [Abstract] [Full Text] [Related]

  • 12. Molecular dynamics studies of CED-4/CED-9/EGL-1 ternary complex reveal CED-4 release mechanism in the linear apoptotic pathway of Caenorhabditis elegans.
    Reddy CN, Sankararamakrishnan R.
    Proteins; 2023 May 17; 91(5):679-693. PubMed ID: 36541866
    [Abstract] [Full Text] [Related]

  • 13. Bcl-2 proteins EGL-1 and CED-9 do not regulate mitochondrial fission or fusion in Caenorhabditis elegans.
    Breckenridge DG, Kang BH, Xue D.
    Curr Biol; 2009 May 12; 19(9):768-73. PubMed ID: 19327994
    [Abstract] [Full Text] [Related]

  • 14. Disruption of the CED-9.CED-4 complex by EGL-1 is a critical step for programmed cell death in Caenorhabditis elegans.
    del Peso L, Gonzalez VM, Inohara N, Ellis RE, Núñez G.
    J Biol Chem; 2000 Sep 01; 275(35):27205-11. PubMed ID: 10846174
    [Abstract] [Full Text] [Related]

  • 15. Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans.
    Deng X, Yin X, Allan R, Lu DD, Maurer CW, Haimovitz-Friedman A, Fuks Z, Shaham S, Kolesnick R.
    Science; 2008 Oct 03; 322(5898):110-5. PubMed ID: 18832646
    [Abstract] [Full Text] [Related]

  • 16. Regulation of apoptosis by C. elegans CED-9 in the absence of the C-terminal transmembrane domain.
    Tan FJ, Fire AZ, Hill RB.
    Cell Death Differ; 2007 Nov 03; 14(11):1925-35. PubMed ID: 17703231
    [Abstract] [Full Text] [Related]

  • 17. Identification of a Bcl-XL binding region within the ATPase domain of Apaf-1.
    Yajima H, Suzuki F.
    Biochem Biophys Res Commun; 2003 Sep 26; 309(3):520-7. PubMed ID: 12963020
    [Abstract] [Full Text] [Related]

  • 18. The BCL-2-like protein CED-9 of C. elegans promotes FZO-1/Mfn1,2- and EAT-3/Opa1-dependent mitochondrial fusion.
    Rolland SG, Lu Y, David CN, Conradt B.
    J Cell Biol; 2009 Aug 24; 186(4):525-40. PubMed ID: 19704021
    [Abstract] [Full Text] [Related]

  • 19. Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death.
    Chinnaiyan AM, O'Rourke K, Lane BR, Dixit VM.
    Science; 1997 Feb 21; 275(5303):1122-6. PubMed ID: 9027312
    [Abstract] [Full Text] [Related]

  • 20. Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans.
    Geng X, Harry BL, Zhou Q, Skeen-Gaar RR, Ge X, Lee ES, Mitani S, Xue D.
    Proc Natl Acad Sci U S A; 2012 Nov 06; 109(45):18465-70. PubMed ID: 23091037
    [Abstract] [Full Text] [Related]

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