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Journal Abstract Search

150 related items for PubMed ID: 3948171

  • 1. Derivatives of 5,6-diphenylpyridazin-3-one: synthetic antimitotic agents which interact with plant and mammalian tubulin at a new drug-binding site.
    Batra JK, Powers LJ, Hess FD, Hamel E.
    Cancer Res; 1986 Apr; 46(4 Pt 2):1889-93. PubMed ID: 3948171
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  • 2. Structure-function studies with derivatives of 6-benzyl-1,3-benzodioxole, a new class of synthetic compounds which inhibit tubulin polymerization and mitosis.
    Batra JK, Jurd L, Hamel E.
    Mol Pharmacol; 1985 Jan; 27(1):94-102. PubMed ID: 3965931
    [Abstract] [Full Text] [Related]

  • 3. Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data.
    Paull KD, Lin CM, Malspeis L, Hamel E.
    Cancer Res; 1992 Jul 15; 52(14):3892-900. PubMed ID: 1617665
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  • 4. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
    Bai R, Cichacz ZA, Herald CL, Pettit GR, Hamel E.
    Mol Pharmacol; 1993 Oct 15; 44(4):757-66. PubMed ID: 8232226
    [Abstract] [Full Text] [Related]

  • 5. Methylenedioxy-benzopyran analogs of podophyllotoxin, a new synthetic class of antimitotic agents that inhibit tubulin polymerization.
    Batra JK, Kang GJ, Jurd L, Hamel E.
    Biochem Pharmacol; 1988 Jul 01; 37(13):2595-602. PubMed ID: 3390218
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  • 6. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
    Gupta K, Bishop J, Peck A, Brown J, Wilson L, Panda D.
    Biochemistry; 2004 Jun 01; 43(21):6645-55. PubMed ID: 15157098
    [Abstract] [Full Text] [Related]

  • 7. Tricyclic pyrone analogs: a new synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro and the growth of solid tumors in vivo.
    Perchellet EM, Ladesich JB, Magill MJ, Chen Y, Hua DH, Perchellet JP.
    Anticancer Drugs; 1999 Jun 01; 10(5):489-504. PubMed ID: 10477169
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  • 9. Natural organic compounds that affect to microtubule functions.
    Iwasaki S.
    Yakugaku Zasshi; 1998 Apr 01; 118(4):112-26. PubMed ID: 9564789
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  • 10. [Immunofluorescent studies on cytoplasmic microtubule complex (CMTC) of Vero cells treated with 5,6-diphenylpyridazin-3-one derivatives].
    Liu ZL.
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 1990 Jun 01; 12(3):213-6. PubMed ID: 1981866
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  • 13. Investigation of the mechanism of the interaction of tubulin with derivatives of 2-styrylquinazolin-4(3H)-one.
    Lin CM, Kang GJ, Roach MC, Jiang JB, Hesson DP, Luduena RF, Hamel E.
    Mol Pharmacol; 1991 Nov 01; 40(5):827-32. PubMed ID: 1944246
    [Abstract] [Full Text] [Related]

  • 14. Interaction of estramustine with tubulin isotypes.
    Laing N, Dahllöf B, Hartley-Asp B, Ranganathan S, Tew KD.
    Biochemistry; 1997 Jan 28; 36(4):871-8. PubMed ID: 9020786
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  • 16. Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data.
    Bai RL, Paull KD, Herald CL, Malspeis L, Pettit GR, Hamel E.
    J Biol Chem; 1991 Aug 25; 266(24):15882-9. PubMed ID: 1874739
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  • 18. Therapeutic selectivity of vinca alkaloids: a role for guanosine 5'-triphosphate?
    Houghton PJ, Houghton JA, Bowman LC, Hazelton BJ.
    Anticancer Drug Des; 1987 Oct 25; 2(2):165-79. PubMed ID: 3329524
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