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Journal Abstract Search

150 related items for PubMed ID: 3948171

  • 21. Binding of maytansine to tubulin: competition with other mitotic inhibitors.
    Lin CM, Hamel E, Wolpert-DeFilippes MK.
    Res Commun Chem Pathol Pharmacol; 1981 Mar; 31(3):443-51. PubMed ID: 7255878
    [Abstract] [Full Text] [Related]

  • 22. LU103793 (NSC D-669356): a synthetic peptide that interacts with microtubules and inhibits mitosis.
    de Arruda M, Cocchiaro CA, Nelson CM, Grinnell CM, Janssen B, Haupt A, Barlozzari T.
    Cancer Res; 1995 Jul 15; 55(14):3085-92. PubMed ID: 7606731
    [Abstract] [Full Text] [Related]

  • 23. Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites.
    Bai RL, Pettit GR, Hamel E.
    J Biol Chem; 1990 Oct 05; 265(28):17141-9. PubMed ID: 2211617
    [Abstract] [Full Text] [Related]

  • 24. Dolastatin 15, a potent antimitotic depsipeptide derived from Dolabella auricularia. Interaction with tubulin and effects of cellular microtubules.
    Bai R, Friedman SJ, Pettit GR, Hamel E.
    Biochem Pharmacol; 1992 Jun 23; 43(12):2637-45. PubMed ID: 1632820
    [Abstract] [Full Text] [Related]

  • 25. Inhibition of tubulin polymerization by 5,6-dihydroindolo[2,1-alpha]isoquinoline derivatives.
    Goldbrunner M, Loidl G, Polossek T, Mannschreck A, von Angerer E.
    J Med Chem; 1997 Oct 24; 40(22):3524-33. PubMed ID: 9357519
    [Abstract] [Full Text] [Related]

  • 26. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
    Tahir SK, Han EK, Credo B, Jae HS, Pietenpol JA, Scatena CD, Wu-Wong JR, Frost D, Sham H, Rosenberg SH, Ng SC.
    Cancer Res; 2001 Jul 15; 61(14):5480-5. PubMed ID: 11454695
    [Abstract] [Full Text] [Related]

  • 27. Characterization of the interaction of the marine cyanobacterial natural product curacin A with the colchicine site of tubulin and initial structure-activity studies with analogues.
    Blokhin AV, Yoo HD, Geralds RS, Nagle DG, Gerwick WH, Hamel E.
    Mol Pharmacol; 1995 Sep 15; 48(3):523-31. PubMed ID: 7565634
    [Abstract] [Full Text] [Related]

  • 28. Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain.
    Bai R, Pettit GR, Hamel E.
    Biochem Pharmacol; 1990 Jun 15; 39(12):1941-9. PubMed ID: 2353935
    [Abstract] [Full Text] [Related]

  • 29. Microtubule disruption induced in vivo by alkylation of beta-tubulin by 1-aryl-3-(2-chloroethyl)ureas, a novel class of soft alkylating agents.
    Legault J, Gaulin JF, Mounetou E, Bolduc S, Lacroix J, Poyet P, Gaudreault RC.
    Cancer Res; 2000 Feb 15; 60(4):985-92. PubMed ID: 10706114
    [Abstract] [Full Text] [Related]

  • 30. Dietary antioxidant curcumin inhibits microtubule assembly through tubulin binding.
    Gupta KK, Bharne SS, Rathinasamy K, Naik NR, Panda D.
    FEBS J; 2006 Dec 15; 273(23):5320-32. PubMed ID: 17069615
    [Abstract] [Full Text] [Related]

  • 31. 3-(Iodoacetamido)-benzoylurea: a novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells.
    Jiang JD, Davis AS, Middleton K, Ling YH, Perez-Soler R, Holland JF, Bekesi JG.
    Cancer Res; 1998 Dec 01; 58(23):5389-95. PubMed ID: 9850070
    [Abstract] [Full Text] [Related]

  • 32. Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin.
    Cruz-Monserrate Z, Vervoort HC, Bai R, Newman DJ, Howell SB, Los G, Mullaney JT, Williams MD, Pettit GR, Fenical W, Hamel E.
    Mol Pharmacol; 2003 Jun 01; 63(6):1273-80. PubMed ID: 12761336
    [Abstract] [Full Text] [Related]

  • 33. Antitumor agents. 174. 2',3',4',5,6,7-Substituted 2-phenyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Chen K, Kuo SC, Hsieh MC, Mauger A, Lin CM, Hamel E, Lee KH.
    J Med Chem; 1997 Jul 04; 40(14):2266-75. PubMed ID: 9216846
    [Abstract] [Full Text] [Related]

  • 34. Laulimalide and paclitaxel: a comparison of their effects on tubulin assembly and their synergistic action when present simultaneously.
    Gapud EJ, Bai R, Ghosh AK, Hamel E.
    Mol Pharmacol; 2004 Jul 04; 66(1):113-21. PubMed ID: 15213302
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  • 35. Interactions of antimitotic peptides and depsipeptides with tubulin.
    Hamel E.
    Biopolymers; 2002 Jul 04; 66(3):142-60. PubMed ID: 12385035
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  • 36. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
    Ouyang X, Piatnitski EL, Pattaropong V, Chen X, He HY, Kiselyov AS, Velankar A, Kawakami J, Labelle M, Smith L, Lohman J, Lee SP, Malikzay A, Fleming J, Gerlak J, Wang Y, Rosler RL, Zhou K, Mitelman S, Camara M, Surguladze D, Doody JF, Tuma MC.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1191-6. PubMed ID: 16377187
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  • 37. Morpholino derivatives of benzyl-benzodioxole, a study of structural requirements for drug interactions at the colchicine/podophyllotoxin binding site of tubulin.
    Batra JK, Jurd L, Hamel E.
    Biochem Pharmacol; 1986 Nov 15; 35(22):4013-8. PubMed ID: 3778522
    [Abstract] [Full Text] [Related]

  • 38. Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
    Lin CM, Singh SB, Chu PS, Dempcy RO, Schmidt JM, Pettit GR, Hamel E.
    Mol Pharmacol; 1988 Aug 15; 34(2):200-8. PubMed ID: 3412321
    [Abstract] [Full Text] [Related]

  • 39. Interaction of vinca alkaloids with tubulin: a comparison of vinblastine, vincristine, and vinorelbine.
    Lobert S, Vulevic B, Correia JJ.
    Biochemistry; 1996 May 28; 35(21):6806-14. PubMed ID: 8639632
    [Abstract] [Full Text] [Related]

  • 40. Synthesis and evaluation of alpha-hydroxymethylated conjugated nitroalkenes for their anticancer activity: inhibition of cell proliferation by targeting microtubules.
    Mohan R, Rastogi N, Namboothiri IN, Mobin SM, Panda D.
    Bioorg Med Chem; 2006 Dec 01; 14(23):8073-85. PubMed ID: 16891118
    [Abstract] [Full Text] [Related]

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