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4. Chymopapain A. Purification and investigation by covalent chromatography and characterization by two-protonic-state reactivity-probe kinetics, steady-state kinetics and resonance Raman spectroscopy of some dithioacyl derivatives. Baines BS, Brocklehurst K, Carey PR, Jarvis M, Salih E, Storer AC. Biochem J; 1986 Jan 01; 233(1):119-29. PubMed ID: 3513753 [Abstract] [Full Text] [Related]
7. Chemical evidence for the pH-dependent control of ion-pair geometry in cathepsin B. Benzofuroxan as a reactivity probe sensitive to differences in the mutual disposition of the thiolate and imidazolium components of cysteine proteinase catalytic sites. Willenbrock F, Brocklehurst K. Biochem J; 1986 Aug 15; 238(1):103-7. PubMed ID: 3800926 [Abstract] [Full Text] [Related]
9. Characterization of the papain active centre by using two-protonic-state electrophiles as reactivity probes. Evidence for nucleophilic reactivity in the un-interrupted cysteine-25-histidine-159 interactive system. Shipton M, Brochlehurst K. Biochem J; 1978 May 01; 171(2):385-401. PubMed ID: 26335 [Abstract] [Full Text] [Related]
10. Reactivities of neutral and cationic forms of 2,2'-dipyridyl disulphide towards thiolate anions. Detection of differences between the active centres of actinidin, papain and ficin by a three-protonic-state reactivity probe. Brocklehurst K, Stuchbury T, Malthouse JP. Biochem J; 1979 Nov 01; 183(2):233-8. PubMed ID: 43130 [Abstract] [Full Text] [Related]
12. Preparation of fully active ficin from Ficus glabrata by covalent chromatography and characterization of its active centre by using 2,2'-depyridyl disulphide as a reactivity probe. Malthouse JP, Brocklehurst K. Biochem J; 1976 Nov 01; 159(2):221-34. PubMed ID: 11777 [Abstract] [Full Text] [Related]
17. Reactions of L-ergothioneine and some other aminothiones with2,2'-and 4,4'-dipyridyl disulphides and of L-ergothioneine with iodoacetamide. 2-Mercaptoimidazoles, 2- and 4-thiopyridones, thiourea and thioacetamide as highly reactive neutral sulphur nucleophils. Carlsson J, Kierstan MP, Brocklehurst K. Biochem J; 1974 Apr 01; 139(1):221-35. PubMed ID: 4463944 [Abstract] [Full Text] [Related]
19. Supracrystallographic resolution of interactions contributing to enzyme catalysis by use of natural structural variants and reactivity-probe kinetics. Brocklehurst K, Brocklehurst SM, Kowlessur D, O'Driscoll M, Patel G, Salih E, Templeton W, Thomas E, Topham CM, Willenbrock F. Biochem J; 1988 Dec 01; 256(2):543-58. PubMed ID: 3223929 [Abstract] [Full Text] [Related]