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Journal Abstract Search

157 related items for PubMed ID: 4625530

  • 1. Folate antagonists. 3. 2,4-Diamino-6-(heterocyclic)quinazolines, a novel class of antimetabolites with potent antimalarial and antibacterial activity.
    Elslager EF, Clarke J, Werbel LM, Worth DF, Davoll J.
    J Med Chem; 1972 Aug; 15(8):827-36. PubMed ID: 4625530
    [No Abstract] [Full Text] [Related]

  • 2. Folate antagonists. 9. 2,4-Diamino-6-((aralkyl)alkylamino)quinazolines, a potent class of antimetabolites with prodigious antimalarial effects.
    Elslager EF, Bird OD, Clarke J, Perricone SC, Worth DF.
    J Med Chem; 1972 Nov; 15(11):1138-46. PubMed ID: 4631920
    [No Abstract] [Full Text] [Related]

  • 3. Folate antagonists. 2. 2,4-Diamino-6-((aralkyl and (heterocyclic)methyl)amino)quinazolines, a novel class of antimetabolites of interest in drug-resistant malaria and Chagas' disease.
    Davoll J, Johnson AM, Davies HJ, Bird OD, Clarke J, Elslager EF.
    J Med Chem; 1972 Aug; 15(8):812-26. PubMed ID: 4625529
    [No Abstract] [Full Text] [Related]

  • 4. Folate antagonists. 4. Antimalarial and antimetabolite effects of 2,4-diamino-6-((benzyl)amino)pyrido(2,3-d)-pyrimidines.
    Davoll J, Clarke J, Elslager EF.
    J Med Chem; 1972 Aug; 15(8):837-9. PubMed ID: 5044297
    [No Abstract] [Full Text] [Related]

  • 5. Folate antagonists. 13. 2,4-Diamino-6-](alpha,alpha,alpha-trifluoro-m-tolyl)thio]quinazoline and related 2,4-diamino-6-[(phenyl- and naphthyl)thio]quinazolines, a unique class of antimetabolites with extraordinary antimalarial and antibacterial effects.
    Elslager EF, Jacob P, Johnson J, Werbel LM, Worth DF, Rane L.
    J Med Chem; 1978 Oct; 21(10):1059-70. PubMed ID: 102792
    [Abstract] [Full Text] [Related]

  • 6. Folate antagonists. 12. Antimalarial and antibacterial effects of 2,4-diamino-6-[(aralkyl and alicyclid)thio-, sulfinyl-, and sulfonyl]quinazolines.
    Elslager EF, Davoll J, Jacob P, Johnson AM, Johnson J, Werbel LM.
    J Med Chem; 1978 Jul; 21(7):639-43. PubMed ID: 97382
    [Abstract] [Full Text] [Related]

  • 7. Folate antagonists. 15. 2,3-Diamino-6-(2-naphthylsulfonyl)quinazoline and related 2,4-diamino-6-[(phenyl and naphthyl)sulfinyl and sulfonyl]quinazolines, a potent new class of antimetabolites with phenomenal antimalarial activity.
    Elslager EF, Hutt MP, Jacob P, Johnson J, Temporelli B, Werbel LM, Worth DF, Rane L.
    J Med Chem; 1979 Oct; 22(10):1247-57. PubMed ID: 117107
    [Abstract] [Full Text] [Related]

  • 8. Quinazolines. 12. 1,3-Diaminobenzo(f)quinazolines containing long-chain alkyl or chloro substituents on the central ring. Synthesis and biological evaluation as candidate antifolate and antimalarial agents.
    Rosowsky A, Huang PC, Papathanasopoulos N, Modest EJ.
    J Med Chem; 1974 Nov; 17(11):1217-22. PubMed ID: 4606974
    [No Abstract] [Full Text] [Related]

  • 9. Folate antagonists. 22. Antimalarial and antibacterial effects of 2,4-diamino-6-quinazolinesulfonamides.
    Elslager EF, Colbry NL, Davoll J, Hutt MP, Johnson JL, Werbel LM.
    J Med Chem; 1984 Dec; 27(12):1740-3. PubMed ID: 6502605
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and evaluation of 6-arylactamido-2,4-diaminoquinazolines and related compounds as folic acid antagonists.
    Hynes JB, Ashton WT.
    J Med Chem; 1975 Mar; 18(3):263-5. PubMed ID: 1094114
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of some bis(2,4-diaminopyrimidines) and bis(2,4-diaminoquinazolines) as potential antimalarial agents.
    Hynes JB, Gratz RF, Ashton WT.
    J Med Chem; 1972 Dec; 15(12):1332-3. PubMed ID: 4629015
    [No Abstract] [Full Text] [Related]

  • 12. Synthesis of 5-substituted quinazolines as potential antimalarial agents.
    Ashton WT, Hynes JB.
    J Med Chem; 1973 Nov; 16(11):1233-7. PubMed ID: 4583883
    [No Abstract] [Full Text] [Related]

  • 13. 2,4-Diaminothieno(2,3-d)pyrimidines as antifolates and antimalarials. 1. Synthesis of 2,4-diamino-5,6,7,8-tetrahydrothianaphthena(2,3-d)pyrimidines and related compounds.
    Rosowsky A, Chaykovsky M, Chen KK, Lin M, Modest EJ.
    J Med Chem; 1973 Mar; 16(3):185-8. PubMed ID: 4632693
    [No Abstract] [Full Text] [Related]

  • 14. Folate antagonists. 20. Synthesis and antitumor and antimalarial properties of trimetrexate and related 6-[(phenylamino)methyl]-2,4-quinazolinediamines.
    Elslager EF, Johnson JL, Werbel LM.
    J Med Chem; 1983 Dec; 26(12):1753-60. PubMed ID: 6227747
    [Abstract] [Full Text] [Related]

  • 15. 2,4-Diaminothieno(2,3-d)pyrimidines as antifolates and antimalarials. 2. Synthesis of 2,4-diaminopyrido(4',3':4,5)thieno(2,3-d)pyrimidines and 2,4-diamino-8H-thiopyrano(4',3':4,5)thieno(2,3-d)pyrimidines.
    Chaykovsky M, Lin M, Rosowsky A, Modest EJ.
    J Med Chem; 1973 Mar; 16(3):188-91. PubMed ID: 4632694
    [No Abstract] [Full Text] [Related]

  • 16. [Studies on antimalarials. IX. Synthesis and antimalarial activity of 2,4-diamino-6-(N-(substituted benzyl)-N-(substituted aminomethyl)-amino) quinazolines].
    Zheng KQ.
    Yao Xue Xue Bao; 1983 May; 18(5):384-7. PubMed ID: 6637492
    [No Abstract] [Full Text] [Related]

  • 17. Synthesis of trimethoprim variations. Replacement of CH 2 by polar groupings.
    Stogryn EL.
    J Med Chem; 1972 Feb; 15(2):200-1. PubMed ID: 4400151
    [No Abstract] [Full Text] [Related]

  • 18. Folate antagonists. 10. Synthesis and antimalarial effects of 6-[[(aryl and aralkyl)amino]methyl]-2,4-pteridinediamines and -pteridinediamine 8-oxides.
    Worth DF, Johnson J, Elslager EF, Werbel LM.
    J Med Chem; 1978 Apr; 21(4):331-7. PubMed ID: 349157
    [Abstract] [Full Text] [Related]

  • 19. [Studies on antimalarials. X. Synthesis and antimalarial activity of derivatives of 2,4-diamino-6-N1,N2-disubstituted hydrazinoquinazoline].
    Zheng KQ, Shen DF, Ni ZG, Chen L, Dai ZR, Ma ZM.
    Yao Xue Xue Bao; 1983 Sep; 18(9):673-7. PubMed ID: 6677053
    [No Abstract] [Full Text] [Related]

  • 20. [Studies on antimalarials. III. Synthesis and antimalarial activities of some derivatives of 2,4-diamino-6-substituted piperazinyl quinazolines (author's transl)].
    Zhang XP, Li GY, Dai ZR, Qian YL, Chen L.
    Yao Xue Xue Bao; 1981 Jun; 16(6):415-24. PubMed ID: 7270168
    [No Abstract] [Full Text] [Related]

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