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Journal Abstract Search

196 related items for PubMed ID: 510534

  • 41. Design, synthesis, and evaluation of a novel sequence-selective epoxide-containing DNA cross-linking agent based on the pyrrolo[2, 1-c][1,4]benzodiazepine system.
    Wilson SC, Howard PW, Forrow SM, Hartley JA, Adams LJ, Jenkins TC, Kelland LR, Thurston DE.
    J Med Chem; 1999 Oct 07; 42(20):4028-41. PubMed ID: 10514273
    [Abstract] [Full Text] [Related]

  • 42. [Research on substances with antiblastic activity. LIV. Tylophera alkaloids. 1. Synthesis of pyrrolo(1,2-b)isoquinoline-10(5H)-one, of benzo(f)pyrrolo(1,2-b)isoquinoline-12(7H)-one and of dibenzo(f,h)pyrrolo(1,2-b)isoquinoline-14(9H)-one].
    De Martino G, Scalzo M, Massa S, Giuliano R.
    Farmaco Sci; 1973 Dec 07; 28(12):976-86. PubMed ID: 4765759
    [No Abstract] [Full Text] [Related]

  • 43.
    ; . PubMed ID:
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  • 44. Chemoselective aromatic azido reduction with concomitant aliphatic azide employing Al/Gd triflates/NaI and ESI-MS mechanistic studies.
    Kamal A, Markandeya N, Shankaraiah N, Reddy CR, Prabhakar S, Reddy CS, Eberlin MN, Silva Santos L.
    Chemistry; 2009 Jul 20; 15(29):7215-24. PubMed ID: 19544509
    [Abstract] [Full Text] [Related]

  • 45. Synthesis of pyrrolo[2,1-c[1,4]benzodiazepines via reductive cyclization of omega-azido carbonyl compounds by TMSI: an efficient preparation of antibiotic DC-81 and its dimers.
    Kamal A, Laxman E, Laxman N, Rao NV.
    Bioorg Med Chem Lett; 2000 Oct 16; 10(20):2311-3. PubMed ID: 11055345
    [Abstract] [Full Text] [Related]

  • 46. Molecular mechanism of binding of pyrrolo(1,4)benzodiazepine antitumour agents to deoxyribonucleic acid--anthramycin and tomaymycin.
    Lown JW, Joshua AV.
    Biochem Pharmacol; 1979 Jul 01; 28(13):2017-26. PubMed ID: 224883
    [No Abstract] [Full Text] [Related]

  • 47. [1,5-benzodiazepines. V. Synthesis of pyrazolo (3,4-b)(1,5)benzodiazepines and 5H-pyrimido(4,5-b)(1,5)benzodiazepines].
    Roma G, Balbi A, Ermili A, Vigevani E.
    Farmaco Sci; 1983 Aug 01; 38(8):546-58. PubMed ID: 6137413
    [Abstract] [Full Text] [Related]

  • 48. 1,2,4-benzothiadiazine linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis, DNA-binding affinity and cytotoxicity.
    Kamal A, Khan MN, Reddy KS, Ahmed SK, Kumar MS, Juvekar A, Sen S, Zingde S.
    Bioorg Med Chem Lett; 2007 Oct 01; 17(19):5345-8. PubMed ID: 17723301
    [Abstract] [Full Text] [Related]

  • 49. Synthesis and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) C8 cyclic amine conjugates.
    Masterson LA, Croker SJ, Jenkins TC, Howard PW, Thurston DE.
    Bioorg Med Chem Lett; 2004 Feb 23; 14(4):901-4. PubMed ID: 15012990
    [Abstract] [Full Text] [Related]

  • 50. Design, synthesis and in vitro cytotoxic studies of novel bis-pyrrolo[2,1][1,4] benzodiazepine-pyrrole and imidazole polyamide conjugates.
    Kumar R, Lown JW.
    Eur J Med Chem; 2005 Jul 23; 40(7):641-54. PubMed ID: 15935899
    [Abstract] [Full Text] [Related]

  • 51. A new strategy for the synthesis of 1,4-benzodiazepine derivatives based on the tandem N-alkylation-ring opening-cyclization reactions of methyl 1-arylaziridine-2-carboxylates with N-[2-bromomethyl(phenyl)]trifluoroacetamides.
    Wang JY, Guo XF, Wang DX, Huang ZT, Wang MX.
    J Org Chem; 2008 Mar 07; 73(5):1979-82. PubMed ID: 18229941
    [Abstract] [Full Text] [Related]

  • 52. Synthesis, DNA-binding ability and evaluation of antitumour activity of triazolo[1,2,4]benzothiadiazine linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates.
    Kamal A, Khan MN, Srikanth YV, Reddy KS, Juvekar A, Sen S, Kurian N, Zingde S.
    Bioorg Med Chem; 2008 Aug 15; 16(16):7804-10. PubMed ID: 18657979
    [Abstract] [Full Text] [Related]

  • 53. Bicyclic and tricyclic analogues of anthramycin.
    Kaneko T, Wong H, Doyle TW, Rose WC, Bradner WT.
    J Med Chem; 1985 Mar 15; 28(3):388-92. PubMed ID: 3973905
    [Abstract] [Full Text] [Related]

  • 54. Synthesis of the first examples of A-C8/C-C2 amide-Linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.
    Gregson SJ, Howard PW, Thurston DE.
    Bioorg Med Chem Lett; 2003 Jul 21; 13(14):2277-80. PubMed ID: 12824017
    [Abstract] [Full Text] [Related]

  • 55. A new and efficient synthesis of pyrrolo[2,3-d]pyrimidine anticancer agents: Alimta (LY231514, MTA), homo-Alimta, TNP-351, and some aryl 5-substituted pyrrolo[2,3-d]pyrimidines.
    Taylor EC, Liu B.
    J Org Chem; 2003 Dec 26; 68(26):9938-47. PubMed ID: 14682686
    [Abstract] [Full Text] [Related]

  • 56. Synthesis and DNA-binding affinity of A-C8/C-C2 alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.
    Kamal A, Ramulu P, Srinivas O, Ramesh G.
    Bioorg Med Chem Lett; 2003 Nov 17; 13(22):3955-8. PubMed ID: 14592483
    [Abstract] [Full Text] [Related]

  • 57. Synthesis and biological evaluation of novel pyrrolo[2,1-c][1,4]benzodiazepine prodrugs for use in antibody-directed enzyme prodrug therapy.
    Masterson LA, Spanswick VJ, Hartley JA, Begent RH, Howard PW, Thurston DE.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):252-6. PubMed ID: 16290933
    [Abstract] [Full Text] [Related]

  • 58. Heterocycles with a benzothiadiazepine moiety. 5. Derivatives of pyrrolo[2,1-d][1,2,5]benzothiadiazepine, a novel tricyclic ring.
    Di Santo R, Costi R, Artico M, Massa S.
    Farmaco; 1997 Jan 15; 52(6-7):375-8. PubMed ID: 9372588
    [Abstract] [Full Text] [Related]

  • 59. Pyrrolo(1,4)benzodiazepine antitumor antibiotics. In vitro interaction of anthramycin, sibiromycin and tomaymycin with DNA using specifically radiolabelled molecules.
    Hurley LH, Gairola C, Zmijewski M.
    Biochim Biophys Acta; 1977 Apr 04; 475(3):521-35. PubMed ID: 15599
    [Abstract] [Full Text] [Related]

  • 60. One-pot synthesis of pyrrolo[1,2-a]quinoxaline derivatives via iron-promoted aryl nitro reduction and aerobic oxidation of alcohols.
    Pereira Mde F, Thiéry V.
    Org Lett; 2012 Sep 21; 14(18):4754-7. PubMed ID: 22971137
    [Abstract] [Full Text] [Related]

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