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134 related items for PubMed ID: 513067

  • 1. Reactions of 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in aqueous solution.
    Weinkam RJ, Lin HS.
    J Med Chem; 1979 Oct; 22(10):1193-8. PubMed ID: 513067
    [Abstract] [Full Text] [Related]

  • 2. Mechanism of action of (2-haloethyl)nitrosoureas on DNA. Isolation and reactions of postulated 2-(alkylimino)-3-nitrosooxazolidine intermediates in the decomposition of 1,3-bis(2-chloroethyl)-, 1-(2-chloroethyl)-3-cyclohexyl-, and 1-(2-chloroethyl)-3-(4'-trans-methylcyclohexyl)-1-nitrosourea.
    Lown JW, Chauhan SM.
    J Med Chem; 1981 Mar; 24(3):270-9. PubMed ID: 7265113
    [Abstract] [Full Text] [Related]

  • 3. Decomposition of N-(2-chloroethyl)-N-nitrosoureas in aqueous media.
    Montgomery JA, James R, McCaleb GS, Kirk MC, Johnston TP.
    J Med Chem; 1975 Jun; 18(6):568-71. PubMed ID: 1151969
    [Abstract] [Full Text] [Related]

  • 4. Mechanism of action of the nitrosoureas--IV. Reactions of bis-chloroethyl nitrosourea and chloroethyl cyclohexyl nitrosourea with deoxyribonucleic acid.
    Gombar CT, Tong WP, Ludlum DB.
    Biochem Pharmacol; 1980 Oct 01; 29(19):2639-43. PubMed ID: 7191706
    [No Abstract] [Full Text] [Related]

  • 5. Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas.
    Kohn KW.
    Cancer Res; 1977 May 01; 37(5):1450-4. PubMed ID: 851960
    [Abstract] [Full Text] [Related]

  • 6. Mechanism of uptake of nitrosoureas by L5178Y lymphoblasts in vitro.
    Begleiter A, Lam HP, Goldenberg GJ.
    Cancer Res; 1977 Apr 01; 37(4):1022-7. PubMed ID: 557367
    [Abstract] [Full Text] [Related]

  • 7. Microsomal metabolism of nitrosoureas.
    Hill DL, Kirk MC, Struck RF.
    Cancer Res; 1975 Feb 01; 35(2):296-301. PubMed ID: 234031
    [Abstract] [Full Text] [Related]

  • 8. Modifications of DNA by different haloethylnitrosoureas.
    Tong WP, Kohn KW, Ludlum DB.
    Cancer Res; 1982 Nov 01; 42(11):4460-4. PubMed ID: 7127289
    [Abstract] [Full Text] [Related]

  • 9. Comparison of biochemical and biological effects of four nitrosoureas with differing carbamoylating activities.
    Kann HE.
    Cancer Res; 1978 Aug 01; 38(8):2363-6. PubMed ID: 149589
    [Abstract] [Full Text] [Related]

  • 10. Effects of nitrosoureas on human DNA polymerase activities from acute and chronic granulocytic leukemia cells.
    Chuang RY, Laszlo J, Keller P.
    Biochim Biophys Acta; 1976 Apr 02; 425(4):463-8. PubMed ID: 1063042
    [Abstract] [Full Text] [Related]

  • 11. Active site specific inactivation of chymotrypsin by cyclohexyl isocyanate formed during degradation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea.
    Babson JR, Reed DJ, Sinkey MA.
    Biochemistry; 1977 Apr 19; 16(8):1584-9. PubMed ID: 856251
    [Abstract] [Full Text] [Related]

  • 12. Effects of carbamoylation on cell survival and DNA repair in normal human embryo cells (IMR-90) treated with various 1-(2-chloroethyl)-1-nitrosoureas.
    Sariban E, Erickson LC, Kohn KW.
    Cancer Res; 1984 Apr 19; 44(4):1352-7. PubMed ID: 6704956
    [Abstract] [Full Text] [Related]

  • 13. 2-chloroethanol formation as evidence for a 2-chloroethyl alkylating intermediate during chemical degradation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.
    Reed DJ, May HE, Boose RB, Gregory KM, Beilstein MA.
    Cancer Res; 1975 Mar 19; 35(3):568-76. PubMed ID: 1116123
    [Abstract] [Full Text] [Related]

  • 14. Metabolism of 1,3-bis(2-chloroethyl)-1-nitrosourea by rat hepatic microsomes.
    Lin HS, Weinkam RJ.
    J Med Chem; 1981 Jun 19; 24(6):761-3. PubMed ID: 7252986
    [Abstract] [Full Text] [Related]

  • 15. Formation of the cross-linked base, diguanylethane, in DNA treated with N,N'-bis(2-chloroethyl)-N-nitrosourea.
    Tong WP, Ludlum DB.
    Cancer Res; 1981 Feb 19; 41(2):380-2. PubMed ID: 7448781
    [Abstract] [Full Text] [Related]

  • 16. A comparison of the lethal effects of three nitrosourea derivatives on cultured human lymphoma cells.
    Drewinko B, Loo TL, Gottlieb JA.
    Cancer Res; 1976 Feb 19; 36(2 Pt 1):511-5. PubMed ID: 1260749
    [Abstract] [Full Text] [Related]

  • 17. Protein mediated chemical reactions of chloroethylnitrosoureas.
    Weinkam RJ, Liu TY, Lin HS.
    Chem Biol Interact; 1980 Aug 19; 31(2):167-77. PubMed ID: 7389008
    [Abstract] [Full Text] [Related]

  • 18. Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture.
    Weinkam RJ, Deen DF.
    Cancer Res; 1982 Mar 19; 42(3):1008-14. PubMed ID: 7059967
    [Abstract] [Full Text] [Related]

  • 19. An analysis of 1-(2-chloroethyl)-1-nitrosourea activity at the cellular level.
    Weinkam RJ, Dolan ME.
    J Med Chem; 1983 Nov 19; 26(11):1656-9. PubMed ID: 6226795
    [Abstract] [Full Text] [Related]

  • 20. Chemical structure of carbamoylating groups and their relationship to bone marrow toxicity and antiglioma activity of bifunctionally alkylating and carbamoylating nitrosoureas.
    Ali-Osman F, Giblin J, Berger M, Murphy MJ, Rosenblum ML.
    Cancer Res; 1985 Sep 19; 45(9):4185-91. PubMed ID: 2411398
    [Abstract] [Full Text] [Related]

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