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Journal Abstract Search

115 related items for PubMed ID: 5188

  • 1. The metabolic activation of the carcinogen 1'-hydroxysafrole in vivo and in vitro and the electrophilic reactivities of possible ultimate carcinogens.
    Wislocki PG, Borchert P, Miller JA, Miller EC.
    Cancer Res; 1976 May; 36(5):1686-95. PubMed ID: 5188
    [Abstract] [Full Text] [Related]

  • 2. N2 atom of guanine and N6 atom of adenine residues as sites for covalent binding of metabolically activated 1'-hydroxysafrole to mouse liver DNA in vivo.
    Phillips DH, Miller JA, Miller EC, Adams B.
    Cancer Res; 1981 Jul; 41(7):2664-71. PubMed ID: 7248936
    [Abstract] [Full Text] [Related]

  • 3. Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.
    Boberg EW, Miller EC, Miller JA, Poland A, Liem A.
    Cancer Res; 1983 Nov; 43(11):5163-73. PubMed ID: 6577945
    [Abstract] [Full Text] [Related]

  • 4. Further characterization of the DNA adducts formed by electrophilic esters of the hepatocarcinogens 1'-hydroxysafrole and 1'-hydroxyestragole in vitro and in mouse liver in vivo, including new adducts at C-8 and N-7 of guanine residues.
    Wiseman RW, Fennell TR, Miller JA, Miller EC.
    Cancer Res; 1985 Jul; 45(7):3096-105. PubMed ID: 4005847
    [Abstract] [Full Text] [Related]

  • 5. Characterization of the biliary and urinary glutathione and N-acetylcysteine metabolites of the hepatic carcinogen 1'-hydroxysafrole and its 1'-oxo metabolite in rats and mice.
    Fennell TR, Miller JA, Miller EC.
    Cancer Res; 1984 Aug; 44(8):3231-40. PubMed ID: 6744260
    [Abstract] [Full Text] [Related]

  • 6. The metabolic sulfonation and side-chain oxidation of 3'-hydroxyisosafrole in the mouse and its inactivity as a hepatocarcinogen relative to 1'-hydroxysafrole.
    Boberg EW, Miller EC, Miller JA.
    Chem Biol Interact; 1986 Aug; 59(1):73-97. PubMed ID: 3757147
    [Abstract] [Full Text] [Related]

  • 7. The in vivo formation and repair of DNA adducts from 1'-hydroxysafrole.
    Phillips DH, Hanawalt PC, Miller JA, Miller EC.
    J Supramol Struct Cell Biochem; 1981 Aug; 16(1):83-90. PubMed ID: 7299840
    [Abstract] [Full Text] [Related]

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  • 10. Metabolic activation of N-hydroxy-N,N'-diacetylbenzidine by hepatic sulfotransferase.
    Morton KC, Beland FA, Evans FE, Fullerton NF, Kadlubar FF.
    Cancer Res; 1980 Mar; 40(3):751-7. PubMed ID: 6937241
    [Abstract] [Full Text] [Related]

  • 11. Metabolism of the proximate carcinogen 1'-hydroxysafrole and the isomer 3'-hydroxyisosafrole.
    Peele JD, Oswald EO.
    Bull Environ Contam Toxicol; 1978 Apr; 19(4):396-402. PubMed ID: 656641
    [No Abstract] [Full Text] [Related]

  • 12. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [Abstract] [Full Text] [Related]

  • 13. The metabolism of the naturally occurring hepatocarcinogen safrole to 1'-hydroxysafrole and the electrophilic reactivity of 1'-acetoxysafrole.
    Borchert P, Wislocki PG, Miller JA, Miller EC.
    Cancer Res; 1973 Mar; 33(3):575-89. PubMed ID: 4689905
    [No Abstract] [Full Text] [Related]

  • 14. Carcinogenic and mutagenic activities of safrole, 1'-hydroxysafrole, and some known or possible metabolites.
    Wislocki PG, Miller EC, Miller JA, McCoy EC, Rosenkranz HS.
    Cancer Res; 1977 Jun; 37(6):1883-91. PubMed ID: 192464
    [No Abstract] [Full Text] [Related]

  • 15. 32P-post-labelling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. I. Adult female CD-1 mice.
    Randerath K, Haglund RE, Phillips DH, Reddy MV.
    Carcinogenesis; 1984 Dec; 5(12):1613-22. PubMed ID: 6499112
    [Abstract] [Full Text] [Related]

  • 16. Major role of hepatic sulfotransferase activity in the metabolic activation, DNA adduct formation, and carcinogenicity of 1'-hydroxy-2',3'-dehydroestragole in infant male C57BL/6J x C3H/HeJ F1 mice.
    Fennell TR, Wiseman RW, Miller JA, Miller EC.
    Cancer Res; 1985 Nov; 45(11 Pt 1):5310-20. PubMed ID: 3863702
    [Abstract] [Full Text] [Related]

  • 17. Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole.
    Miller EC, Swanson AB, Phillips DH, Fletcher TL, Liem A, Miller JA.
    Cancer Res; 1983 Mar; 43(3):1124-34. PubMed ID: 6825084
    [Abstract] [Full Text] [Related]

  • 18. Structures of hepatic nucleic acid-bound dyes in rats given the carcinogen N-methyl-4-aminoazobenzene.
    Lin JK, Miller JA, Miller EC.
    Cancer Res; 1975 Mar; 35(3):844-50. PubMed ID: 1116139
    [Abstract] [Full Text] [Related]

  • 19. Microsomal N-oxidation of the hepatocarcinogen N-methyl-4-aminoazobenzene and the reactivity of N-hydroxy-N-methyl-4-aminoazobenzene.
    Kadlubar FF, Miller JA, Miller EC.
    Cancer Res; 1976 Mar; 36(3):1196-1206. PubMed ID: 814998
    [Abstract] [Full Text] [Related]

  • 20. Differences in the covalent binding of benzo[a]pyrene, safrole, 1'-hydroxysafrole, and 4-aminobiphenyl to DNA of pregnant and non-pregnant mice.
    Lu LJ, Disher RM, Randerath K.
    Cancer Lett; 1986 Apr; 31(1):43-52. PubMed ID: 3697953
    [Abstract] [Full Text] [Related]

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