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Journal Abstract Search

83 related items for PubMed ID: 538078

  • 1. Kinetic evidence for multiple chemically reactive intermediates in the breakdown of phenacetin N-O-glucuronide.
    Hinson JA, Andrews LS, Gillette JR.
    Pharmacology; 1979; 19(5):237-48. PubMed ID: 538078
    [Abstract] [Full Text] [Related]

  • 2. Reactive metabolites of phenacetin and acetaminophen: a review.
    Hinson JA.
    Environ Health Perspect; 1983 Mar; 49():71-9. PubMed ID: 6339229
    [Abstract] [Full Text] [Related]

  • 3. Conversion of the N-Q-glucuronide and N-O-sulfate conjugates of N-hydroxyphenacetin to reactive intermediates.
    Mulder GJ, Hinson JA, Gillette JR.
    Biochem Pharmacol; 1978 Mar; 27(12):1641-9. PubMed ID: 697905
    [No Abstract] [Full Text] [Related]

  • 4. Metabolism of phenacetin and N-hydroxyphenacetin in isolated rat hepatocytes.
    McLean S.
    Naunyn Schmiedebergs Arch Pharmacol; 1978 Nov; 305(2):173-80. PubMed ID: 732893
    [Abstract] [Full Text] [Related]

  • 5. The metabolism of N-hydroxyphenacetin in vitro and in vivo.
    Fischbach T, Lenk W.
    Xenobiotica; 1985 Nov; 15(11):915-27. PubMed ID: 4082632
    [Abstract] [Full Text] [Related]

  • 6. Species-specific activation of phenacetin into bacterial mutagens by hamster liver enzymes and identification of N-hydroxyphenacetin O-glucuronide as a promutagen in the urine.
    Camus AM, Friesen M, Croisy A, Bartsch H.
    Cancer Res; 1982 Aug; 42(8):3201-8. PubMed ID: 7046920
    [Abstract] [Full Text] [Related]

  • 7. N-Hydroxyacetaminophen: a microsomal metabolite of N-hydroxyphenacetin but apparently not of acetaminophen.
    Hinson JA, Pohl LR, Gillette JR.
    Life Sci; 1979 Jun 04; 24(23):2133-8. PubMed ID: 481103
    [No Abstract] [Full Text] [Related]

  • 8. N-hydroxyphenacetin, a new urinary metabolite of phenacetin in the rat.
    McLean S, Davies NW, Watson H, Favretto WA, Bignall JC.
    Drug Metab Dispos; 1981 Jun 04; 9(3):255-60. PubMed ID: 6113936
    [Abstract] [Full Text] [Related]

  • 9. Formation of reactive metabolites of phenacetin in humans and rats.
    Veronese ME, McLean S, D'Souza CA, Davies NW.
    Xenobiotica; 1985 Nov 04; 15(11):929-40. PubMed ID: 4082633
    [Abstract] [Full Text] [Related]

  • 10. Phenacetin and acetaminophen metabolism in the isolated perfused rat liver. Precursor concentration influences the selection of kinetic parameters to assess hypoxic impairment.
    Studenberg SD, Brouwer KL.
    Drug Metab Dispos; 1991 Nov 04; 19(2):423-9. PubMed ID: 1676648
    [Abstract] [Full Text] [Related]

  • 11. High-performance liquid chromatographic assay for acetaminophen and phenacetin in the presence of their metabolites in biological fluids.
    Pang KS, Taburet AM, Hinson JA, Gillette JR.
    J Chromatogr; 1979 Jun 01; 174(1):165-75. PubMed ID: 546886
    [Abstract] [Full Text] [Related]

  • 12. Formation of chemically reactive metabolites of phenacetin and acetaminophen.
    Gillette JR, Nelson SD, Mulder GJ, Jollow DJ, Mitchell JR, Pohl LR, Hinson JA.
    Adv Exp Med Biol; 1981 Jun 01; 136 Pt B():931-50. PubMed ID: 6953755
    [No Abstract] [Full Text] [Related]

  • 13. Interaction of human serum albumin with the electrophilic metabolite 1-O-gemfibrozil-beta-D-glucuronide.
    Sallustio BC, Fairchild BA, Pannall PR.
    Drug Metab Dispos; 1997 Jan 01; 25(1):55-60. PubMed ID: 9010630
    [Abstract] [Full Text] [Related]

  • 14. Kinetics of metabolite formation and elimination in the perfused rat liver preparation: differences between the elimination of preformed acetaminophen and acetaminophen formed from phenacetin.
    Pang KS, Gillette JR.
    J Pharmacol Exp Ther; 1978 Oct 01; 207(1):178-94. PubMed ID: 702339
    [Abstract] [Full Text] [Related]

  • 15. Monitoring in situ liver metabolism in rats using microdialysis. Comparison of microdialysis mass-transport model predictions to experimental metabolite generation data.
    Stenken JA, Ståhle L, Lunte CE, Southard MZ.
    J Pharm Sci; 1998 Mar 01; 87(3):311-20. PubMed ID: 9523984
    [Abstract] [Full Text] [Related]

  • 16. Generation of reactive metabolites of N-hydroxy-phenacetin by glucoronidation and sulfation.
    Mulder GJ, Hinson JA, Gillette JR.
    Biochem Pharmacol; 1977 Feb 01; 26(3):189-96. PubMed ID: 402923
    [No Abstract] [Full Text] [Related]

  • 17. Metabolism and nephrotoxicity of phenacetin and sulfanilamide.
    Eyanagi R, Shigematsu H, Yoshida K, Yoshimura H.
    J Pharmacobiodyn; 1985 Feb 01; 8(2):95-105. PubMed ID: 4009405
    [Abstract] [Full Text] [Related]

  • 18. Metabolite kinetics: formation of acetaminophen from deuterated and nondeuterated phenacetin and acetanilide on acetaminophen sulfation kinetics in the perfused rat liver preparation.
    Pang KS, Waller L, Horning MG, Chan KK.
    J Pharmacol Exp Ther; 1982 Jul 01; 222(1):14-9. PubMed ID: 7086695
    [Abstract] [Full Text] [Related]

  • 19. Comparative metabolic studies of phenacetin and structurally-related compounds in the rat.
    Smith GE, Griffiths LA.
    Xenobiotica; 1976 Apr 01; 6(4):217-36. PubMed ID: 936643
    [Abstract] [Full Text] [Related]

  • 20. Study of the ability of phenacetin, acetaminophen, and aspirin to induce cytotoxicity, mutation, and morphological transformation in C3H/10T1/2 clone 8 mouse embryo cells.
    Patierno SR, Lehman NL, Henderson BE, Landolph JR.
    Cancer Res; 1989 Feb 15; 49(4):1038-44. PubMed ID: 2912548
    [Abstract] [Full Text] [Related]

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