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Journal Abstract Search

151 related items for PubMed ID: 5479856

  • 1.
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  • 2. Irreversible enzyme inhibitors. 178. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 1-(4-benzyloxy-3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with a terminal sulfonyl fluoride.
    Baker BR, Ashton WT.
    J Med Chem; 1970 Nov; 13(6):1161-5. PubMed ID: 5479857
    [No Abstract] [Full Text] [Related]

  • 3. Irreversible enzyme inhibitors. CLXXIX. Active-site-directed irreversible enzyme inhibitors of dihydrofolate reductase from 1-(3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with oxyamide bridges to a terminal sulfonyl fluoride.
    Baker BR, Ashton WT.
    J Med Chem; 1970 Nov; 13(6):1165-70. PubMed ID: 5479858
    [No Abstract] [Full Text] [Related]

  • 4. Irreversible enzyme inhibitors. CLX. Some factors in cell wall transport of active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(phenylalkylphenyl)-s-triazines.
    Baker BR, Janson EE, Vermeulen NM.
    J Med Chem; 1969 Sep; 12(5):898-902. PubMed ID: 5812208
    [No Abstract] [Full Text] [Related]

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  • 6. Irreversible enzyme inhibitors. CXII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine substituted with a terminal sulfonyl fluoride. II.
    Baker BR, Lourens GJ.
    J Med Chem; 1968 Jan; 11(1):38-41. PubMed ID: 5237173
    [No Abstract] [Full Text] [Related]

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  • 8. Irreversible enzyme inhibitors. CXLI. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 1-[p-(p-fluorosulfonylphenylureidomethyl)phenyl]-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine.
    Baker BR, Lourens GJ.
    J Med Chem; 1969 Jan; 12(1):101-4. PubMed ID: 5763002
    [No Abstract] [Full Text] [Related]

  • 9. Irreversible enzyme inhibitors. CXXXIX. p-(4,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)phenylpropionylsulfanilyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase. VI. Further studies on effects of substitution on the propionamide bridge on isozyme specificity.
    Baker BR, Lourens GJ.
    J Med Chem; 1969 Jan; 12(1):92-4. PubMed ID: 5763049
    [No Abstract] [Full Text] [Related]

  • 10. Irreversible enzyme inhibitors. CXL. Active-site-directed irreversible inhibitors derived from 1-(3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine.
    Baker BR, Lourens GJ.
    J Med Chem; 1969 Jan; 12(1):95-101. PubMed ID: 5763050
    [No Abstract] [Full Text] [Related]

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  • 13. Active-site directed irreversible inhibitors of dihydrofolate reductase.
    Baker BR.
    Ann N Y Acad Sci; 1971 Nov 30; 186():214-26. PubMed ID: 4943574
    [No Abstract] [Full Text] [Related]

  • 14. Irreversible enzyme inhibitors. CV. Differential irreversible inhibition of vertebrate dihydrofolic reductases by derivatives of 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazines substituted with a terminal sulfonyl fluoride.
    Baker BR, Lourens GJ.
    J Med Chem; 1967 Nov 30; 10(6):1113-22. PubMed ID: 6056040
    [No Abstract] [Full Text] [Related]

  • 15. Irreversible enzyme inhibitors. CLIX. Effect of substitution on transport and isozyme specificity of p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)-o-chlorophenoxyacetamido-benzenesulfonyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase.
    Baker BR, Ashton WT.
    J Med Chem; 1969 Sep 30; 12(5):894-7. PubMed ID: 5812207
    [No Abstract] [Full Text] [Related]

  • 16. Irreversible enzyme inhibitors. 173. Cure of Walker 256 ascites by reversible and irreversible inhibitors of dihydrofolic reductase derived from 1-(substituted-phenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine.
    Baker BR, Vermeulen NM, Ashton WT, Ryan AJ.
    J Med Chem; 1970 Nov 30; 13(6):1130-40. PubMed ID: 5479852
    [No Abstract] [Full Text] [Related]

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  • 19. Irreversible enzyme inhibitors. 197. Water-soluble reversible inhibitors of dihydrofolate reductase with potent antitumor activity derived from 4, 6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine.
    Baker BR, Ashton WT.
    J Med Chem; 1973 Mar 30; 16(3):209-14. PubMed ID: 4733101
    [No Abstract] [Full Text] [Related]

  • 20. Irreversible enzyme inhibitors. 133. Studies on differential irreversible inhibition of dihydrofolic reductase from three strains of L1210 leukemia, liver, spleen, and intestine of the mouse.
    Baker BR, Lourens GJ, Meyer RB, Vermeulen NM.
    J Med Chem; 1969 Jan 30; 12(1):67-73. PubMed ID: 5763043
    [No Abstract] [Full Text] [Related]

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