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Journal Abstract Search

165 related items for PubMed ID: 6120808

  • 1. Identification of 4-oxo-13-cis-retinoic acid as the major metabolite of 13-cis-retinoic acid in human blood.
    Vane FM, Buggé CJ.
    Drug Metab Dispos; 1981; 9(6):515-20. PubMed ID: 6120808
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of 13-cis-retinoic acid by a rat liver 9000g supernatant preparation.
    Vane FM, Buggé CJ, Williams TH.
    Drug Metab Dispos; 1982; 10(3):212-9. PubMed ID: 6125352
    [Abstract] [Full Text] [Related]

  • 3. Oxidative and reductive metabolism of 9-cis-retinoic acid in the rat. Identification of 13,14-dihydro-9-cis-retinoic acid and its taurine conjugate.
    Shirley MA, Bennani YL, Boehm MF, Breau AP, Pathirana C, Ulm EH.
    Drug Metab Dispos; 1996 Mar; 24(3):293-302. PubMed ID: 8820419
    [Abstract] [Full Text] [Related]

  • 4. Plasma pharmacokinetics and metabolism of 13-cis- and all-trans-retinoic acid in the cynomolgus monkey and the identification of 13-cis- and all-trans-retinoyl-beta-glucuronides. A comparison to one human case study with isotretinoin.
    Kraft JC, Slikker W, Bailey JR, Roberts LG, Fischer B, Wittfoht W, Nau H.
    Drug Metab Dispos; 1991 Mar; 19(2):317-24. PubMed ID: 1676630
    [Abstract] [Full Text] [Related]

  • 5. Metabolism of oral 9-cis-retinoic acid in the human. Identification of 9-cis-retinoyl-beta-glucuronide and 9-cis-4-oxo-retinoyl-beta-glucuronide as urinary metabolites.
    Sass JO, Masgrau E, Saurat JH, Nau H.
    Drug Metab Dispos; 1995 Sep; 23(9):887-91. PubMed ID: 8565776
    [Abstract] [Full Text] [Related]

  • 6. Determination of 13-cis-retinoic acid and its major metabolite, 4-oxo-13-cis-retinoic acid, in human blood by reversed-phase high-performance liquid chromatography.
    Vane FM, Stoltenborg JK, Buggé CJ.
    J Chromatogr; 1982 Feb 12; 227(2):471-84. PubMed ID: 6460777
    [Abstract] [Full Text] [Related]

  • 7. Teratogenicity of isotretinoin revisited: species variation and the role of all-trans-retinoic acid.
    Nau H.
    J Am Acad Dermatol; 2001 Nov 12; 45(5):S183-7. PubMed ID: 11606951
    [Abstract] [Full Text] [Related]

  • 8. Steady state pharmacokinetics of oral treatment with 13-cis-retinoic acid or all-trans-retinoic acid in male and female adult rats.
    Ferguson SA, Siitonen PH, Cisneros FJ, Gough B, Young JF.
    Basic Clin Pharmacol Toxicol; 2006 Jun 12; 98(6):582-7. PubMed ID: 16700821
    [Abstract] [Full Text] [Related]

  • 9. Maternal toxicokinetics, metabolism, and embryo exposure following a teratogenic dosing regimen with 13-cis-retinoic acid (isotretinoin) in the cynomolgus monkey.
    Hummler H, Hendrickx AG, Nau H.
    Teratology; 1994 Sep 12; 50(3):184-93. PubMed ID: 7871482
    [Abstract] [Full Text] [Related]

  • 10. The metabolism and pharmacokinetics of isotretinoin in patients with acne and rosacea are not influenced by ethanol.
    Grønhøj Larsen F, Jakobsen P, Grønhøj Larsen C, Heidenheim M, Held E, Nielsen-Kudsk F.
    Br J Dermatol; 2009 Sep 12; 161(3):664-70. PubMed ID: 19563582
    [Abstract] [Full Text] [Related]

  • 11. Identification of 9,13-dicis-retinoic acid as a major plasma metabolite of 9-cis-retinoic acid and limited transfer of 9-cis-retinoic acid and 9,13-dicis-retinoic acid to the mouse and rat embryos.
    Tzimas G, Sass JO, Wittfoht W, Elmazar MM, Ehlers K, Nau H.
    Drug Metab Dispos; 1994 Sep 12; 22(6):928-36. PubMed ID: 7895612
    [Abstract] [Full Text] [Related]

  • 12. The high sensitivity of the rabbit to the teratogenic effects of 13-cis-retinoic acid (isotretinoin) is a consequence of prolonged exposure of the embryo to 13-cis-retinoic acid and 13-cis-4-oxo-retinoic acid, and not of isomerization to all-trans-retinoic acid.
    Tzimas G, Bürgin H, Collins MD, Hummler H, Nau H.
    Arch Toxicol; 1994 Sep 12; 68(2):119-28. PubMed ID: 8179481
    [Abstract] [Full Text] [Related]

  • 13. Method to determine 4-oxo-retinoic acids, retinoic acids and retinol in serum and cell extracts by liquid chromatography/diode-array detection atmospheric pressure chemical ionisation tandem mass spectrometry.
    Rühl R.
    Rapid Commun Mass Spectrom; 2006 Sep 12; 20(16):2497-504. PubMed ID: 16862622
    [Abstract] [Full Text] [Related]

  • 14. Metabolic characteristics of 13-cis-retinoic acid (isotretinoin) and anti-tumour activity of the 13-cis-retinoic acid metabolite 4-oxo-13-cis-retinoic acid in neuroblastoma.
    Sonawane P, Cho HE, Tagde A, Verlekar D, Yu AL, Reynolds CP, Kang MH.
    Br J Pharmacol; 2014 Dec 12; 171(23):5330-44. PubMed ID: 25039756
    [Abstract] [Full Text] [Related]

  • 15. Pharmacokinetics of 13-cis-, all-trans-, 13-cis-4-oxo-, and all-trans-4-oxo retinoic acid after intravenous administration in the cynomolgus monkey.
    Sandberg JA, Eckhoff C, Nau H, Slikker W.
    Drug Metab Dispos; 1994 Dec 12; 22(1):154-60. PubMed ID: 8149876
    [Abstract] [Full Text] [Related]

  • 16. Teratogenicity and transplacental pharmacokinetics of 13-cis-retinoic acid in rabbits.
    Eckhoff C, Chari S, Kromka M, Staudner H, Juhasz L, Rudiger H, Agnish N.
    Toxicol Appl Pharmacol; 1994 Mar 12; 125(1):34-41. PubMed ID: 8128493
    [Abstract] [Full Text] [Related]

  • 17. Xenopus laevis: a model system for the study of embryonic retinoid metabolism. III. Isomerization and metabolism of all-trans-retinoic acid and 9-cis-retinoic acid and their dysmorphogenic effects in embryos during neurulation.
    Kraft JC, Juchau MR.
    Drug Metab Dispos; 1995 Oct 12; 23(10):1058-71. PubMed ID: 8654193
    [Abstract] [Full Text] [Related]

  • 18. Comparative teratology and transplacental pharmacokinetics of all-trans-retinoic acid, 13-cis-retinoic acid, and retinyl palmitate following daily administrations in rats.
    Collins MD, Tzimas G, Hummler H, Bürgin H, Nau H.
    Toxicol Appl Pharmacol; 1994 Jul 12; 127(1):132-44. PubMed ID: 8048045
    [Abstract] [Full Text] [Related]

  • 19. 13-cis-retinoic acid metabolism in vivo. The major tissue metabolites in the rat have the all-trans configuration.
    McCormick AM, Kroll KD, Napoli JL.
    Biochemistry; 1983 Aug 02; 22(16):3933-40. PubMed ID: 6577913
    [Abstract] [Full Text] [Related]

  • 20. Low teratogenicity of 13-cis-retinoic acid (isotretinoin) in the mouse corresponds to low embryo concentrations during organogenesis: comparison to the all-trans isomer.
    Kraft JC, Kochhar DM, Scott WJ, Nau H.
    Toxicol Appl Pharmacol; 1987 Mar 15; 87(3):474-82. PubMed ID: 3470977
    [Abstract] [Full Text] [Related]

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