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146 related items for PubMed ID: 6130768

  • 1. Studies on the mechanism of action of 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193)--II. Relationship between dose level and biochemical effects in P388 leukemia in vivo.
    Jayaram HN, Smith AL, Glazer RI, Johns DG, Cooney DA.
    Biochem Pharmacol; 1982 Dec 01; 31(23):3839-45. PubMed ID: 6130768
    [Abstract] [Full Text] [Related]

  • 2. Mechanism of resistance to the oncolytic C-nucleoside 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC-286193).
    Jayaram HN, Cooney DA, Glazer RI, Dion RL, Johns DG.
    Biochem Pharmacol; 1982 Aug 01; 31(15):2557-60. PubMed ID: 7126269
    [No Abstract] [Full Text] [Related]

  • 3. Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193).
    Jayaram HN, Dion RL, Glazer RI, Johns DG, Robins RK, Srivastava PC, Cooney DA.
    Biochem Pharmacol; 1982 Jul 15; 31(14):2371-80. PubMed ID: 6127085
    [No Abstract] [Full Text] [Related]

  • 4. The conversion of 2-beta-D-ribofuranosylthiazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties.
    Cooney DA, Jayaram HN, Gebeyehu G, Betts CR, Kelley JA, Marquez VE, Johns DG.
    Biochem Pharmacol; 1982 Jun 01; 31(11):2133-6. PubMed ID: 6126195
    [No Abstract] [Full Text] [Related]

  • 5. Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity.
    Cooney DA, Jayaram HN, Glazer RI, Kelley JA, Marquez VE, Gebeyehu G, Van Cott AC, Zwelling LA, Johns DG.
    Adv Enzyme Regul; 1983 Jun 01; 21():271-303. PubMed ID: 6152729
    [Abstract] [Full Text] [Related]

  • 6. Studies on the mechanism of action of 2-beta-D-ribofuranosylthiazole-4-carboxamide--V. Factors governing the response of murine tumors to tiazofurin.
    Ahluwalia GS, Jayaram HN, Plowman JP, Cooney DA, Johns DG.
    Biochem Pharmacol; 1984 Apr 15; 33(8):1195-203. PubMed ID: 6143562
    [Abstract] [Full Text] [Related]

  • 7. Studies on the mechanism of action of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide). VI. Biochemical and pharmacological studies on the degradation of thiazole-4-carboxamide adenine dinucleotide (TAD).
    Ahluwalia GS, Cooney DA, Marquez VE, Jayaram HN, Johns DG.
    Biochem Pharmacol; 1986 Nov 01; 35(21):3783-90. PubMed ID: 2877671
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  • 12. Phase I evaluation and pharmacokinetics of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193).
    Melink TJ, Von Hoff DD, Kuhn JG, Hersh MR, Sternson LA, Patton TF, Siegler R, Boldt DH, Clark GM.
    Cancer Res; 1985 Jun 01; 45(6):2859-65. PubMed ID: 3986813
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  • 13. Biochemical differences among four inosinate dehydrogenase inhibitors, mycophenolic acid, ribavirin, tiazofurin, and selenazofurin, studied in mouse lymphoma cell culture.
    Lee HJ, Pawlak K, Nguyen BT, Robins RK, Sadée W.
    Cancer Res; 1985 Nov 01; 45(11 Pt 1):5512-20. PubMed ID: 2865005
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  • 15. IMP dehydrogenase: inhibition by the anti-leukemic drug, tiazofurin.
    Yamada Y, Natsumeda Y, Yamaji Y, Jayaram HN, Tricot GJ, Hoffman R, Weber G.
    Leuk Res; 1989 Nov 01; 13(2):179-84. PubMed ID: 2564451
    [Abstract] [Full Text] [Related]

  • 16. Comparative in vitro studies of Tiazofurin and a selenazole analog.
    Streeter DG, Robins RK.
    Biochem Biophys Res Commun; 1983 Sep 15; 115(2):544-50. PubMed ID: 6138036
    [Abstract] [Full Text] [Related]

  • 17. Mechanism of resistance to tiazofurin in hepatoma 3924A.
    Jayaram HN, Pillwein K, Lui MS, Faderan MA, Weber G.
    Biochem Pharmacol; 1986 Feb 15; 35(4):587-93. PubMed ID: 2868729
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  • 18. Biochemical mechanisms of resistance to tiazofurin.
    Jayaram HN.
    Adv Enzyme Regul; 1985 Feb 15; 24():67-89. PubMed ID: 3835825
    [Abstract] [Full Text] [Related]

  • 19. Furanfurin and thiophenfurin: two novel tiazofurin analogues. Synthesis, structure, antitumor activity, and interactions with inosine monophosphate dehydrogenase.
    Franchetti P, Cappellacci L, Grifantini M, Barzi A, Nocentini G, Yang H, O'Connor A, Jayaram HN, Carrell C, Goldstein BM.
    J Med Chem; 1995 Sep 15; 38(19):3829-37. PubMed ID: 7562914
    [Abstract] [Full Text] [Related]

  • 20. Targets and markers of selective action of tiazofurin.
    Weber G, Natsumeda Y, Pillwein K.
    Adv Enzyme Regul; 1985 Sep 15; 24():45-65. PubMed ID: 2424286
    [Abstract] [Full Text] [Related]

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