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142 related items for PubMed ID: 6135572
21. Metabolic activation of norethisterone (norethindrone) to an irreversibly protein-bound derivative by rat liver microsomes. Kappus H, Remmer H. Drug Metab Dispos; 1975; 3(5):338-44. PubMed ID: 241614 [Abstract] [Full Text] [Related]
22. Metabolism and covalent binding of [14C]toluene by human and rat liver microsomal fractions and liver slices. Chapman DE, Moore TJ, Michener SR, Powis G. Drug Metab Dispos; 1990; 18(6):929-36. PubMed ID: 1981539 [Abstract] [Full Text] [Related]
23. The inhibition of rat hepatic microsomal propranolol metabolism by a covalently bound reactive metabolite. Pritchard JF, Schneck DW, Hayes AH. Res Commun Chem Pathol Pharmacol; 1980 Feb; 27(2):211-22. PubMed ID: 6768117 [Abstract] [Full Text] [Related]
24. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine. Zhao SX, Dalvie DK, Kelly JM, Soglia JR, Frederick KS, Smith EB, Obach RS, Kalgutkar AS. Chem Res Toxicol; 2007 Nov; 20(11):1649-57. PubMed ID: 17907785 [Abstract] [Full Text] [Related]
25. DT-diaphorase and peroxidase influence the covalent binding of the metabolites of phenol, the major metabolite of benzene. Smart RC, Zannoni VG. Mol Pharmacol; 1984 Jul; 26(1):105-11. PubMed ID: 6749127 [Abstract] [Full Text] [Related]
26. Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate. Masubuchi Y, Igarashi S, Suzuki T, Horie T, Narimatsu S. J Pharmacol Exp Ther; 1996 Nov; 279(2):724-31. PubMed ID: 8930177 [Abstract] [Full Text] [Related]
31. In vitro studies on the metabolic activation of the furanopyridine L-754,394, a highly potent and selective mechanism-based inhibitor of cytochrome P450 3A4. Sahali-Sahly Y, Balani SK, Lin JH, Baillie TA. Chem Res Toxicol; 1996 Sep; 9(6):1007-12. PubMed ID: 8870989 [Abstract] [Full Text] [Related]
32. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole. Woodcroft KJ, Webb CD, Yao M, Weedon AC, Bend JR. Chem Res Toxicol; 1997 May; 10(5):589-99. PubMed ID: 9168258 [Abstract] [Full Text] [Related]
33. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver. Amato G, Longo V, Mazzaccaro A, Gervasi PG. Chem Res Toxicol; 1996 May; 9(5):882-90. PubMed ID: 8828925 [Abstract] [Full Text] [Related]
34. Formation of nontoxic reactive metabolites of p-bromophenol. Identification of a new glutathione conjugate. Monks TJ, Lau SS, Highet RJ. Drug Metab Dispos; 1984 May; 12(4):432-7. PubMed ID: 6148209 [Abstract] [Full Text] [Related]
35. Metabolic activation of the nitroaromatic antiandrogen flutamide by rat and human cytochromes P-450, including forms belonging to the 3A and 1A subfamilies. Berson A, Wolf C, Chachaty C, Fisch C, Fau D, Eugene D, Loeper J, Gauthier JC, Beaune P, Pompon D. J Pharmacol Exp Ther; 1993 Apr; 265(1):366-72. PubMed ID: 8386241 [Abstract] [Full Text] [Related]
36. In vitro studies on irreversible binding of halothane metabolite to microsomes. Van Dyke RA, Wood CL. Drug Metab Dispos; 1975 Apr; 3(1):51-7. PubMed ID: 234835 [Abstract] [Full Text] [Related]
38. The formation of procainamide hydroxylamine by rat and human liver microsomes. Budinsky RA, Roberts SM, Coats EA, Adams L, Hess EV. Drug Metab Dispos; 1987 Apr; 15(1):37-43. PubMed ID: 2881757 [Abstract] [Full Text] [Related]