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333 related items for PubMed ID: 6243137

  • 1. Variant human phosphoribosylpyrophosphate synthetase altered in regulatory and catalytic functions.
    Becker MA, Raivio KO, Bakay B, Adams WB, Nyhan WL.
    J Clin Invest; 1980 Jan; 65(1):109-20. PubMed ID: 6243137
    [Abstract] [Full Text] [Related]

  • 2. Gout with superactive phosphoribosylpyrophosphate synthetase due to increased enzyme catalytic rate.
    Becker MA, Losman MJ, Itkin P, Simkin PA.
    J Lab Clin Med; 1982 Apr; 99(4):495-511. PubMed ID: 6174658
    [Abstract] [Full Text] [Related]

  • 3. Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction.
    Becker MA.
    J Clin Invest; 1976 Feb; 57(2):308-18. PubMed ID: 176178
    [Abstract] [Full Text] [Related]

  • 4. Mutant feedback-resistant phosphoribosylpyrophosphate synthetase associated with purine overproduction and gout. Phosphoribosylpyrophosphate and purine metabolism in cultured fibroblasts.
    Zoref E, De Vries A, Sperling O.
    J Clin Invest; 1975 Nov; 56(5):1093-9. PubMed ID: 171280
    [Abstract] [Full Text] [Related]

  • 5. Superactivity of phosphoribosylpyrophosphate synthetase, due to feedback resistance, causing purine overproduction and gout.
    Sperling O, Boer P, Brosh S, Zoref E, de Vries A.
    Ciba Found Symp; 1977 Nov; (48):143-64. PubMed ID: 204460
    [Abstract] [Full Text] [Related]

  • 6. Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness.
    Becker MA, Puig JG, Mateos FA, Jimenez ML, Kim M, Simmonds HA.
    Am J Med; 1988 Sep; 85(3):383-90. PubMed ID: 2843048
    [Abstract] [Full Text] [Related]

  • 7. Mechanisms of accelerated purine nucleotide synthesis in human fibroblasts with superactive phosphoribosylpyrophosphate synthetases.
    Becker MA, Losman MJ, Kim M.
    J Biol Chem; 1987 Apr 25; 262(12):5596-602. PubMed ID: 3032938
    [Abstract] [Full Text] [Related]

  • 8. Superactivity of human phosphoribosyl pyrophosphate synthetase due to altered regulation by nucleotide inhibitors and inorganic phosphate.
    Becker MA, Losman MJ, Wilson J, Simmonds HA.
    Biochim Biophys Acta; 1986 Jun 19; 882(2):168-76. PubMed ID: 2423135
    [Abstract] [Full Text] [Related]

  • 9. Regulation of purine synthesis de novo in human fibroblasts by purine nucleotides and phosphoribosylpyrophosphate.
    Becker MA, Kim M.
    J Biol Chem; 1987 Oct 25; 262(30):14531-7. PubMed ID: 2444588
    [Abstract] [Full Text] [Related]

  • 10. Phosphoribosylpyrophosphate synthetase superactivity. A study of five patients with catalytic defects in the enzyme.
    Becker MA, Losman MJ, Rosenberg AL, Mehlman I, Levinson DJ, Holmes EW.
    Arthritis Rheum; 1986 Jul 25; 29(7):880-8. PubMed ID: 3017368
    [Abstract] [Full Text] [Related]

  • 11. Human phosphoribosylpyrophosphate synthetase. Comparison of purified normal and mutant enzymes.
    Becker MA, Kostel PJ, Meyer LJ.
    J Biol Chem; 1975 Sep 10; 250(17):6822-30. PubMed ID: 169259
    [Abstract] [Full Text] [Related]

  • 12. Regulation of purine nucleotide synthesis in human B lymphoblasts with both hypoxanthine-guanine phosphoribosyltransferase deficiency and phosphoribosylpyrophosphate synthetase superactivity.
    Becker MA, Kim M, Husain K, Kang T.
    J Biol Chem; 1992 Mar 05; 267(7):4317-21. PubMed ID: 1311306
    [Abstract] [Full Text] [Related]

  • 13. Human phosphoribosylpyrophosphate synthetase: radioimmunochemical quantitation in erythrocytes and fibroblasts.
    Itkin P, Woo S, Becker MA.
    J Lab Clin Med; 1984 Jul 05; 104(1):96-109. PubMed ID: 6330252
    [Abstract] [Full Text] [Related]

  • 14. Superactive phosphoribosylpyrophosphate synthetase with altered regulatory and catalytic properties.
    Becker MA, Raivio KO, Bakay B, Adams WB, Nyhan WL.
    Adv Exp Med Biol; 1980 Jul 05; 122A():387-92. PubMed ID: 6158850
    [No Abstract] [Full Text] [Related]

  • 15. Selective expression of phosphoribosylpyrophosphate synthetase superactivity in human lymphoblast lines.
    Losman MJ, Rimon D, Kim M, Becker MA.
    J Clin Invest; 1985 Oct 05; 76(4):1657-64. PubMed ID: 2414323
    [Abstract] [Full Text] [Related]

  • 16. Overproduction disease in man due to enzyme feedback resistance mutation. Purine overproduction in gout due to excessive activity of mutant feedback-resistant phosphoribosylpyrophosphate synthetase.
    Sperling O, Boer P, Brosh S, Zoref E, de Vries A.
    Enzyme; 1978 Oct 05; 23(1):1-9. PubMed ID: 203449
    [Abstract] [Full Text] [Related]

  • 17. Regulation of purine nucleotide synthesis. Effects of inosine on normal and hypoxantine-guanine phosphoribosyltransferase-deficient fibroblasts.
    Becker MA.
    Biochim Biophys Acta; 1976 Jun 18; 435(2):132-44. PubMed ID: 938674
    [Abstract] [Full Text] [Related]

  • 18. Diagnostic evaluation of phosphoribosylpyrophosphate synthetase activities in hemolysates.
    Losman MJ, Hecker S, Woo S, Becker MA.
    J Lab Clin Med; 1984 Jun 18; 103(6):932-43. PubMed ID: 6327865
    [Abstract] [Full Text] [Related]

  • 19. Decreased phosphoribosylpyrophosphate as the basis for decreased purine synthesis during amino acid starvation of human lymphoblasts.
    Boss GR.
    J Biol Chem; 1984 Mar 10; 259(5):2936-41. PubMed ID: 6199353
    [Abstract] [Full Text] [Related]

  • 20. Evidence for X-linkage of human phosphoribosylpyrophosphate synthetase.
    Yen RC, Adams WB, Lazar C, Becker MA.
    Proc Natl Acad Sci U S A; 1978 Jan 10; 75(1):482-5. PubMed ID: 203941
    [Abstract] [Full Text] [Related]

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