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Journal Abstract Search

167 related items for PubMed ID: 6262301

  • 1. Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 reductase produces DNA cleavage in a reaction mediated by molecular oxygen.
    Berlin V, Haseltine WA.
    J Biol Chem; 1981 May 25; 256(10):4747-56. PubMed ID: 6262301
    [Abstract] [Full Text] [Related]

  • 2. Enzymic- and thiol-mediated activation of halogen-substituted diaziridinylbenzoquinones: redox transitions of the semiquinone and semiquinone-thioether species.
    Goin J, Giulivi C, Butler J, Cadenas E.
    Free Radic Biol Med; 1995 Mar 25; 18(3):525-36. PubMed ID: 9101243
    [Abstract] [Full Text] [Related]

  • 3. NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals.
    Bachur NR, Gordon SL, Gee MV, Kon H.
    Proc Natl Acad Sci U S A; 1979 Feb 25; 76(2):954-7. PubMed ID: 34156
    [Abstract] [Full Text] [Related]

  • 4. Clear evidence for the participation of OH in lambda DNA breakage induced by the enzymatic reduction of adriamycin in the presence of iron-ADP. Importance of local OH concentration for DNA strand cleavage.
    Sugioka K, Nakano H, Tsuchiya J, Nakano M, Sugioka Y, Tero-Kubota S, Ikegami Y.
    Biochem Int; 1984 Aug 25; 9(2):237-42. PubMed ID: 6435634
    [Abstract] [Full Text] [Related]

  • 5. Adriamycin-enhanced membrane lipid peroxidation in isolated rat nuclei.
    Mimnaugh EG, Kennedy KA, Trush MA, Sinha BK.
    Cancer Res; 1985 Jul 25; 45(7):3296-304. PubMed ID: 2988766
    [Abstract] [Full Text] [Related]

  • 6. DNA damage by superoxide-generating systems in relation to the mechanism of action of the anti-tumour antibiotic adriamycin.
    Rowley DA, Halliwell B.
    Biochim Biophys Acta; 1983 Nov 22; 761(1):86-93. PubMed ID: 6315070
    [Abstract] [Full Text] [Related]

  • 7. Generation of hydroxyl radical by anticancer quinone drugs, carbazilquinone, mitomycin C, aclacinomycin A and adriamycin, in the presence of NADPH-cytochrome P-450 reductase.
    Komiyama T, Kikuchi T, Sugiura Y.
    Biochem Pharmacol; 1982 Nov 15; 31(22):3651-6. PubMed ID: 6295407
    [Abstract] [Full Text] [Related]

  • 8. Oxygen consumption and oxyradical production from microsomal reduction of aqueous extracts of cigarette tar.
    Winston GW, Church DF, Cueto R, Pryor WA.
    Arch Biochem Biophys; 1993 Aug 01; 304(2):371-8. PubMed ID: 8394056
    [Abstract] [Full Text] [Related]

  • 9. Free radical formation and DNA strand breakage during metabolism of diaziquone by NAD(P)H quinone-acceptor oxidoreductase (DT-diaphorase) and NADPH cytochrome c reductase.
    Fisher GR, Gutierrez PL.
    Free Radic Biol Med; 1991 Aug 01; 11(6):597-607. PubMed ID: 1663902
    [Abstract] [Full Text] [Related]

  • 10. NADPH-dependent production of oxy radicals by purified components of the rat liver mixed function oxidase system. I. Oxidation of hydroxyl radical scavenging agents.
    Winston GW, Cederbaum AI.
    J Biol Chem; 1983 Feb 10; 258(3):1508-13. PubMed ID: 6296101
    [Abstract] [Full Text] [Related]

  • 11. Interactions of anticancer quinone drugs, aclacinomycin A, adriamycin, carbazilquinone, and mitomycin C, with NADPH-cytochrome P-450 reductase, xanthine oxidase and oxygen.
    Komiyama T, Kikuchi T, Sugiura Y.
    J Pharmacobiodyn; 1986 Aug 10; 9(8):651-64. PubMed ID: 3023600
    [Abstract] [Full Text] [Related]

  • 12. Hydroxyl radical generation and DNA strand scission mediated by natural anticancer and synthetic quinones.
    Rumyantseva GV, Weiner LM, Frolova EI, Fedorova OS.
    FEBS Lett; 1989 Jan 02; 242(2):397-400. PubMed ID: 2536625
    [Abstract] [Full Text] [Related]

  • 13. DNA strand scission by polycyclic aromatic hydrocarbon o-quinones: role of reactive oxygen species, Cu(II)/Cu(I) redox cycling, and o-semiquinone anion radicals,
    Flowers L, Ohnishi ST, Penning TM.
    Biochemistry; 1997 Jul 15; 36(28):8640-8. PubMed ID: 9214311
    [Abstract] [Full Text] [Related]

  • 14. Adriamycin activation and oxygen free radical formation in human breast tumor cells: protective role of glutathione peroxidase in adriamycin resistance.
    Sinha BK, Mimnaugh EG, Rajagopalan S, Myers CE.
    Cancer Res; 1989 Jul 15; 49(14):3844-8. PubMed ID: 2544260
    [Abstract] [Full Text] [Related]

  • 15. Enzymatic activation and binding of adriamycin to nuclear DNA.
    Sinha BK, Trush MA, Kennedy KA, Mimnaugh EG.
    Cancer Res; 1984 Jul 15; 44(7):2892-6. PubMed ID: 6327028
    [Abstract] [Full Text] [Related]

  • 16. Generation of hydroxyl radicals during the enzymatic reductions of the Fe3+-ADP-phosphate-adriamycin and Fe3+-ADP-EDTA systems. Less involvement of hydroxyl radical and a great importance of proposed perferryl ion complexes in lipid peroxidation.
    Sugioka K, Nakano H, Nakano M, Tero-Kubota S, Ikegami Y.
    Biochim Biophys Acta; 1983 Oct 11; 753(3):411-21. PubMed ID: 6311278
    [Abstract] [Full Text] [Related]

  • 17. Bioreduction of idarubicin and formation of ROS responsible for DNA cleavage by NADPH-cytochrome P450 reductase and its potential role in the antitumor effect.
    Celik H, Arinç E.
    J Pharm Pharm Sci; 2008 Oct 11; 11(4):68-82. PubMed ID: 19183515
    [Abstract] [Full Text] [Related]

  • 18. Involvement of NADPH: cytochrome P450 reductase in the activation of indoloquinone EO9 to free radical and DNA damaging species.
    Bailey SM, Lewis AD, Patterson LH, Fisher GR, Knox RJ, Workman P.
    Biochem Pharmacol; 2001 Aug 15; 62(4):461-8. PubMed ID: 11448456
    [Abstract] [Full Text] [Related]

  • 19. Free radical production from normal and adriamycin-treated rat cardiac sarcosomes.
    Thornalley PJ, Dodd NJ.
    Biochem Pharmacol; 1985 Mar 01; 34(5):669-74. PubMed ID: 2983734
    [Abstract] [Full Text] [Related]

  • 20. The effect of the anthrapyrazole antitumour agent CI941 on rat liver microsome and cytochrome P-450 reductase mediated free radical processes. Inhibition of doxorubicin activation in vitro.
    Graham MA, Newell DR, Butler J, Hoey B, Patterson LH.
    Biochem Pharmacol; 1987 Oct 15; 36(20):3345-51. PubMed ID: 2823819
    [Abstract] [Full Text] [Related]

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