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86 related items for PubMed ID: 6307307

  • 1. Tissue and substrate specificity of inhibition by alkoxy-aryl-lactams of platelet and arterial smooth muscle cyclic nucleotide phosphodiesterases relationship to pharmacological activity.
    Lugnier C, Stierlé A, Beretz A, Schoeffter P, Lebec A, Wermuth CG, Cazenave JP, Stoclet JC.
    Biochem Biophys Res Commun; 1983 Jun 29; 113(3):954-9. PubMed ID: 6307307
    [Abstract] [Full Text] [Related]

  • 2. Selective inhibition of cyclic nucleotide phosphodiesterases of human, bovine and rat aorta.
    Lugnier C, Schoeffter P, Le Bec A, Strouthou E, Stoclet JC.
    Biochem Pharmacol; 1986 May 15; 35(10):1743-51. PubMed ID: 2423089
    [Abstract] [Full Text] [Related]

  • 3. Purification and properties of the cGMP-inhibited cAMP phosphodiesterase from bovine aortic smooth muscle.
    Rascón A, Lindgren S, Stavenow L, Belfrage P, Andersson KE, Manganiello VC, Degerman E.
    Biochim Biophys Acta; 1992 Mar 16; 1134(2):149-56. PubMed ID: 1313303
    [Abstract] [Full Text] [Related]

  • 4. Differential pharmacologic sensitivity of cyclic nucleotide phosphodiesterase isozymes isolated from cardiac muscle, arterial and airway smooth muscle.
    Silver PJ, Hamel LT, Perrone MH, Bentley RG, Bushover CR, Evans DB.
    Eur J Pharmacol; 1988 May 20; 150(1-2):85-94. PubMed ID: 2841146
    [Abstract] [Full Text] [Related]

  • 5. Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity.
    Sudo T, Tachibana K, Toga K, Tochizawa S, Inoue Y, Kimura Y, Hidaka H.
    Biochem Pharmacol; 2000 Feb 15; 59(4):347-56. PubMed ID: 10644042
    [Abstract] [Full Text] [Related]

  • 6. Purification of cyclic adenosine monophosphate phosphodiesterase from human platelets using new-inhibitor Sepharose chromatography.
    Umekawa H, Tanaka T, Kimura Y, Hidaka H.
    Biochem Pharmacol; 1984 Nov 01; 33(21):3339-44. PubMed ID: 6093810
    [Abstract] [Full Text] [Related]

  • 7. 7-Bromo-1,5-dihydro-3,6-dimethylimidazo[2,1-b]quinazolin-2(3H)- one (Ro 15-2041), a potent antithrombotic agent that selectively inhibits platelet cyclic AMP-phosphodiesterase.
    Muggli R, Tschopp TB, Mittelholzer E, Baumgartner HR.
    J Pharmacol Exp Ther; 1985 Oct 01; 235(1):212-9. PubMed ID: 2995647
    [Abstract] [Full Text] [Related]

  • 8. Imidazoquinoline derivatives: potent inhibitors of platelet cAMP phosphodiesterase which elevate cAMP levels and activate protein kinase in platelets.
    Seiler S, Gillespie E, Arnold AJ, Brassard CL, Meanwell NA, Fleming JS.
    Thromb Res; 1991 Apr 01; 62(1-2):31-42. PubMed ID: 1649498
    [Abstract] [Full Text] [Related]

  • 9. Inhibitors of cyclic AMP phosphodiesterase. 1. Analogues of cilostamide and anagrelide.
    Jones GH, Venuti MC, Alvarez R, Bruno JJ, Berks AH, Prince A.
    J Med Chem; 1987 Feb 01; 30(2):295-303. PubMed ID: 3027338
    [Abstract] [Full Text] [Related]

  • 10. Selective effects of phosphodiesterase inhibitors on different phosphodiesterases, adenosine 3',5'-monophosphate metabolism, and lipolysis in 3T3-L1 adipocytes.
    Elks ML, Manganiello VC.
    Endocrinology; 1984 Oct 01; 115(4):1262-8. PubMed ID: 6207009
    [Abstract] [Full Text] [Related]

  • 11. Selective inhibitor of platelet cyclic adenosine monophosphate phosphodiesterase, cilostamide, inhibits platelet aggregation.
    Hidaka H, Hayashi H, Kohri H, Kimura Y, Hosokawa T, Igawa T, Saitoh Y.
    J Pharmacol Exp Ther; 1979 Oct 01; 211(1):26-30. PubMed ID: 226672
    [No Abstract] [Full Text] [Related]

  • 12. Y-590 (a new pyridazinone derivative), a potent anti-thrombotic agent--II. Inhibition of platelet phosphodiesterase.
    Mikashima H, Nakao T, Goto K, Ochi H, Yasuda H, Tsumagari T.
    Thromb Res; 1984 Sep 01; 35(5):589-94. PubMed ID: 6091293
    [Abstract] [Full Text] [Related]

  • 13. In vitro and in vivo inhibitory effects of propentofylline on cyclic AMP phosphodiesterase activity.
    Nagata K, Ogawa T, Omosu M, Fujimoto K, Hayashi S.
    Arzneimittelforschung; 1985 Sep 01; 35(7):1034-6. PubMed ID: 2996562
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of human platelet cyclic AMP phosphodiesterase and of platelet aggregation by a hemisynthetic flavonoid, amentoflavone hexaacetate.
    Beretz A, Briançon-Scheid F, Stierlé A, Corre G, Anton R, Cazenave JP.
    Biochem Pharmacol; 1986 Jan 15; 35(2):257-62. PubMed ID: 3002388
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of platelet aggregation by the cAMP-phosphodiesterase inhibitor, cilostamide, may not be associated with activation of cAMP-dependent protein kinase.
    Nishikawa M, Komada F, Morita K, Deguchi K, Shirakawa S.
    Cell Signal; 1992 Jul 15; 4(4):453-63. PubMed ID: 1329900
    [Abstract] [Full Text] [Related]

  • 16. Two isoforms of cGMP-inhibited cyclic nucleotide phosphodiesterases in human tissues distinguished by their responses to vesnarinone, a new cardiotonic agent.
    Masuoka H, Ito M, Sugioka M, Kozeki H, Konishi T, Tanaka T, Nakano T.
    Biochem Biophys Res Commun; 1993 Jan 29; 190(2):412-7. PubMed ID: 8381275
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of the low Km cyclic AMP phosphodiesterase and activation of the cyclic AMP system in vascular smooth muscle by milrinone.
    Silver PJ, Lepore RE, O'Connor B, Lemp BM, Hamel LT, Bentley RG, Harris AL.
    J Pharmacol Exp Ther; 1988 Oct 29; 247(1):34-42. PubMed ID: 2845058
    [Abstract] [Full Text] [Related]

  • 18. Possible role of cyclic AMP phosphodiesterases in the actions of ibudilast on eosinophil thromboxane generation and airways smooth muscle tone.
    Souness JE, Villamil ME, Scott LC, Tomkinson A, Giembycz MA, Raeburn D.
    Br J Pharmacol; 1994 Apr 29; 111(4):1081-8. PubMed ID: 8032594
    [Abstract] [Full Text] [Related]

  • 19. A potent and selective inhibitor of cyclic AMP phosphodiesterase with potential cardiotonic and antithrombotic properties.
    Alvarez R, Banerjee GL, Bruno JJ, Jones GL, Littschwager K, Strosberg AM, Venuti MC.
    Mol Pharmacol; 1986 Jun 29; 29(6):554-60. PubMed ID: 3012320
    [Abstract] [Full Text] [Related]

  • 20. Effects of isozyme-selective phosphodiesterase inhibitors on rat aorta and human platelets: smooth muscle tone, platelet aggregation and cAMP levels.
    Lindgren SH, Andersson TL, Vinge E, Andersson KE.
    Acta Physiol Scand; 1990 Oct 29; 140(2):209-19. PubMed ID: 2176433
    [Abstract] [Full Text] [Related]

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