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705 related items for PubMed ID: 6317640

  • 1. DNA strand breaks and poly(ADP-ribose) synthetase activation in pancreatic islets--a new aspect to development of insulin-dependent diabetes and pancreatic B-cell tumors.
    Okamoto H, Yamamoto H.
    Princess Takamatsu Symp; 1983; 13():297-308. PubMed ID: 6317640
    [Abstract] [Full Text] [Related]

  • 2. The role of poly(ADP-ribose) synthetase in the development of insulin-dependent diabetes and islet B-cell regeneration.
    Okamoto H.
    Biomed Biochim Acta; 1985; 44(1):15-20. PubMed ID: 2986610
    [No Abstract] [Full Text] [Related]

  • 3. Induction of rat pancreatic B-cell tumors by the combined administration of streptozotocin or alloxan and poly(adenosine diphosphate ribose) synthetase inhibitors.
    Yamagami T, Miwa A, Takasawa S, Yamamoto H, Okamoto H.
    Cancer Res; 1985 Apr; 45(4):1845-9. PubMed ID: 2983889
    [Abstract] [Full Text] [Related]

  • 4. Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets.
    Yamamoto H, Uchigata Y, Okamoto H.
    Nature; 1981 Nov 19; 294(5838):284-6. PubMed ID: 6272129
    [No Abstract] [Full Text] [Related]

  • 5. Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis.
    Uchigata Y, Yamamoto H, Kawamura A, Okamoto H.
    J Biol Chem; 1982 Jun 10; 257(11):6084-8. PubMed ID: 6281256
    [Abstract] [Full Text] [Related]

  • 6. Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD+ depletion.
    Radons J, Heller B, Bürkle A, Hartmann B, Rodriguez ML, Kröncke KD, Burkart V, Kolb H.
    Biochem Biophys Res Commun; 1994 Mar 30; 199(3):1270-7. PubMed ID: 8147870
    [Abstract] [Full Text] [Related]

  • 7. Effect of poly(ADP-ribose) synthetase inhibitor administration to rats before and after injection of alloxan and streptozotocin on islet proinsulin synthesis.
    Uchigata Y, Yamamoto H, Nagai H, Okamoto H.
    Diabetes; 1983 Apr 30; 32(4):316-8. PubMed ID: 6299867
    [Abstract] [Full Text] [Related]

  • 8. Protection by picolinamide, a novel inhibitor of poly (ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets.
    Yamamoto H, Okamoto H.
    Biochem Biophys Res Commun; 1980 Jul 16; 95(1):474-81. PubMed ID: 6251809
    [No Abstract] [Full Text] [Related]

  • 9. Effects of environmental factors on the development of insulin-dependent diabetes mellitus.
    Yoon JW, Kim CJ, Pak CY, McArthur RG.
    Clin Invest Med; 1987 Sep 16; 10(5):457-69. PubMed ID: 3315367
    [Abstract] [Full Text] [Related]

  • 10. Survival and B-cell function of mouse pancreatic islets maintained in culture after concomitant exposure to streptozotocin and nicotinamide.
    Strandell E, Eizirik DL, Sandler S.
    Exp Clin Endocrinol; 1989 May 16; 93(2-3):219-24. PubMed ID: 2528468
    [Abstract] [Full Text] [Related]

  • 11. Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.
    Burkart V, Wang ZQ, Radons J, Heller B, Herceg Z, Stingl L, Wagner EF, Kolb H.
    Nat Med; 1999 Mar 16; 5(3):314-9. PubMed ID: 10086388
    [Abstract] [Full Text] [Related]

  • 12. Poly(ADP-ribose) polymerase mediates the suicide response to massive DNA damage: studies in normal and DNA-repair defective cells.
    Berger NA, Sims JL, Catino DM, Berger SJ.
    Princess Takamatsu Symp; 1983 Mar 16; 13():219-26. PubMed ID: 6317637
    [Abstract] [Full Text] [Related]

  • 13. Poly(ADP-ribose) synthetase inhibitors enhance streptozotocin-induced killing of insulinoma cells by inhibiting the repair of DNA strand breaks.
    Yamamoto H, Okamoto H.
    FEBS Lett; 1982 Aug 23; 145(2):298-302. PubMed ID: 6290270
    [No Abstract] [Full Text] [Related]

  • 14. Temperature sensitivity of poly(ADP-ribose) synthetase in intact cells.
    Kidwell WR, Purnell MR.
    Princess Takamatsu Symp; 1983 Aug 23; 13():243-52. PubMed ID: 6317639
    [Abstract] [Full Text] [Related]

  • 15. Poly(ADP-ribose) in the cellular response to DNA damage.
    Berger NA.
    Radiat Res; 1985 Jan 23; 101(1):4-15. PubMed ID: 3155867
    [Abstract] [Full Text] [Related]

  • 16. Streptozotocin diabetes. Correlation with extent of depression of pancreatic islet nicotinamide adenine dinucleotide.
    Anderson T, Schein PS, McMenamin MG, Cooney DA.
    J Clin Invest; 1974 Sep 23; 54(3):672-7. PubMed ID: 4369217
    [Abstract] [Full Text] [Related]

  • 17. Streptozotocin-induced impairment of islet B-cell metabolism and its prevention by a hydroxyl radical scavenger and inhibitors of poly(ADP-ribose) synthetase.
    Sandler S, Welsh M, Andersson A.
    Acta Pharmacol Toxicol (Copenh); 1983 Nov 23; 53(5):392-400. PubMed ID: 6318515
    [Abstract] [Full Text] [Related]

  • 18. Protection by 3-aminobenzamide and nicotinamide against streptozotocin-induced beta-cell toxicity in vivo and in vitro.
    Masiello P, Novelli M, Fierabracci V, Bergamini E.
    Res Commun Chem Pathol Pharmacol; 1990 Jul 23; 69(1):17-32. PubMed ID: 2145620
    [Abstract] [Full Text] [Related]

  • 19. Differential target molecules for toxicity induced by streptozotocin and alloxan in pancreatic islets of mice in vitro.
    Gai W, Schott-Ohly P, Schulte im Walde S, Gleichmann H.
    Exp Clin Endocrinol Diabetes; 2004 Jan 23; 112(1):29-37. PubMed ID: 14758569
    [Abstract] [Full Text] [Related]

  • 20. DNA repair synthesis in the pancreatic islets of streptozotocin-treated mice.
    Sandler S, Swenne I.
    Diabetes Res; 1985 Sep 23; 2(5):255-8. PubMed ID: 2933209
    [Abstract] [Full Text] [Related]

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