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113 related items for PubMed ID: 6411369

  • 1. Interactions between the active metabolite of tryptophan pyrolysate mutagen, N-hydroxy-Trp-P-2, and lipids: the role of lipid peroxides in the conversion of N-hydroxy-Trp-P-2 to non-reactive forms.
    Saito K, Yamazoe Y, Kamataki T, Kato R.
    Chem Biol Interact; 1983 Aug 01; 45(3):295-304. PubMed ID: 6411369
    [Abstract] [Full Text] [Related]

  • 2. Structural elucidation of a mutagenic metabolite of 3-amino-1-methyl-5H-pyrido[4,3-b]indole.
    Yamazoe Y, Ishii K, Kamataki T, Kato R.
    Drug Metab Dispos; 1981 Aug 01; 9(3):292-6. PubMed ID: 6113943
    [Abstract] [Full Text] [Related]

  • 3. Metabolic activation of trp-P-2, a mutagenic amine from tryptophan-pyrolysate, by liver microsomes from 3-methylcholanthrene-responsive and non-responsive mice.
    Yamazoe Y, Yamaguchi N, Kamataki T, Kato R.
    Xenobiotica; 1980 Aug 01; 10(7-8):483-94. PubMed ID: 7445519
    [Abstract] [Full Text] [Related]

  • 4. Isolation and characterization of active metabolites of tryptophan-pyrolysate mutagen, TRP-P-2, formed by rat liver microsomes.
    Yamazoe Y, Ishii K, Kamataki T, Kato R, Sugimura T.
    Chem Biol Interact; 1980 May 01; 30(2):125-38. PubMed ID: 6771024
    [Abstract] [Full Text] [Related]

  • 5. Metabolic activation of 3-amino-5H-pyrido[4,3-b]indole, a highly mutagenic principle in tryptophan pyrolysate, by rat liver enzymes.
    Nemoto N, Kusumi S, Takayama S, Nagao M, Sugimura T.
    Chem Biol Interact; 1979 Oct 01; 27(2-3):191-8. PubMed ID: 498354
    [Abstract] [Full Text] [Related]

  • 6. Reactions of potent mutagens, 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) and 2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1) with nucleic acid.
    Hashimoto Y, Shudo K, Imamura M, Okamoto T.
    Nucleic Acids Symp Ser; 1980 Oct 01; (8):s109-12. PubMed ID: 7255181
    [Abstract] [Full Text] [Related]

  • 7. Activation and detoxication of N-hydroxy-Trp-P-2 by glutathione and glutathione transferases.
    Saito K, Yamazoe Y, Kamataki T, Kato R.
    Carcinogenesis; 1983 Dec 01; 4(12):1551-7. PubMed ID: 6360405
    [Abstract] [Full Text] [Related]

  • 8. Activation of a mutagen, 3-amino-1-methyl-5H-pyrido[4,3-b]indole. Identification of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole and its reacion with DNA.
    Hashimoto Y, Shudo K, Okamoto T.
    Biochem Biophys Res Commun; 1980 Sep 16; 96(1):355-62. PubMed ID: 7437040
    [No Abstract] [Full Text] [Related]

  • 9. Glutathione transferase-mediated and non-enzymatic activation and detoxication of the N-hydroxy derivative of Trp-P-2, a potent pyrolysate promutagen.
    Saito K, Yamazoe Y, Kamataki T, Kato R.
    Xenobiotica; 1984 Jul 16; 14(7):545-8. PubMed ID: 6506768
    [Abstract] [Full Text] [Related]

  • 10. DNA binding of N-hydroxy-Trp-P-2 and N-hydroxy-Glu-P-1 by acetyl-CoA dependent enzyme in mammalian liver cytosol.
    Shinohara A, Saito K, Yamazoe Y, Kamataki T, Kato R.
    Carcinogenesis; 1985 Feb 16; 6(2):305-7. PubMed ID: 3971494
    [Abstract] [Full Text] [Related]

  • 11. Species difference in N-hydroxylation of a tryptophan pyrolysis product in relation to mutagenic activation.
    Yamazoe Y, Kamataki T, Kato R.
    Cancer Res; 1981 Nov 16; 41(11 Pt 1):4518-22. PubMed ID: 6796262
    [Abstract] [Full Text] [Related]

  • 12. Evidence for the involvement of N-hydroxylation of 3-amino-1-methyl-5H-pyrido[4,3-b]indole by cytochrome P-450 in the covalent binding to DNA.
    Mita S, Ishii K, Yamazoe Y, Kamataki T, Kato R, Sugimura T.
    Cancer Res; 1981 Sep 16; 41(9 Pt 1):3610-4. PubMed ID: 7020934
    [Abstract] [Full Text] [Related]

  • 13. Catalysis of the covalent binding of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole to DNA by a L-proline- and adenosine triphosphate-dependent enzyme in rat hepatic cytosol.
    Yamazoe Y, Shimada M, Shinohara A, Saito K, Kamataki T, Kato R.
    Cancer Res; 1985 Jun 16; 45(6):2495-500. PubMed ID: 3986789
    [Abstract] [Full Text] [Related]

  • 14. Mutagenic activation of 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole(Trp-P-1) and 3-amino-1-methyl-5H-pyrido(4,3-b)indole (Trp-P-2) by primary cultures of adult rat hepatocytes: effect of Aroclor induction in vitro.
    Decloître F, Hamon G, Martin M, Thybaud-Lambay V.
    Mutat Res; 1984 Jun 16; 137(2-3):123-32. PubMed ID: 6433191
    [Abstract] [Full Text] [Related]

  • 15. Electrochemical determination for enzymic production of ultimate carcinogen from tryptophan pyrolysate by rat hepatic microsomes.
    Minamoto S, Kanazawa K.
    Anal Biochem; 1995 Feb 10; 225(1):143-8. PubMed ID: 7778765
    [Abstract] [Full Text] [Related]

  • 16. Absorption of 3-amino-1-methyl-5H-pyrido[4,3-b]indole, a mutagen-carcinogen present in tryptophan pyrolysate, from the gastro-intestinal tract in the rat.
    Kimura T, Nakayama T, Kurosaki Y, Suzuki Y, Arimoto S, Hayatsu H.
    Jpn J Cancer Res; 1985 Apr 10; 76(4):272-7. PubMed ID: 3924701
    [Abstract] [Full Text] [Related]

  • 17. Metabolic activation of Trp-P-2, a tryptophan-pyrolysis mutagen, by isolated rat hepatocytes.
    Mita S, Yamazoe Y, Kamataki T, Kato R.
    Biochem Pharmacol; 1983 Apr 01; 32(7):1179-82. PubMed ID: 6189495
    [Abstract] [Full Text] [Related]

  • 18. Metabolic activation of 2-amino-9H-pyrido[2,3-b]indole by rat-liver microsomes.
    Niwa T, Yamazoe Y, Kato R.
    Mutat Res; 1982 Aug 01; 95(2-3):159-70. PubMed ID: 6750381
    [Abstract] [Full Text] [Related]

  • 19. Metabolic activation of a tryptophan pyrolysis product, 3-amino-1-methyl-5H-pyrido[4,3-b]indole(TRP-P-2) by isolated rat liver nuclei.
    Mita S, Yamazoe Y, Kamataki T, Kato R.
    Cancer Lett; 1981 Dec 01; 14(3):261-6. PubMed ID: 6800639
    [Abstract] [Full Text] [Related]

  • 20. Sex-dependent induction of hepatic enzymes for mutagenic activation of a tryptophan pyrolysate component, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]-indole, by feeding in mice.
    Degawa M, Kojima M, Hishinuma T, Hashimoto Y.
    Cancer Res; 1985 Jan 01; 45(1):96-102. PubMed ID: 3880668
    [Abstract] [Full Text] [Related]

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