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PUBMED FOR HANDHELDS

Journal Abstract Search


131 related items for PubMed ID: 6490649

  • 1. A novel class of genetic variants of the L1210 cell up-regulated for folate analogue transport inward. Isolation, characterization, and degree of metabolic instability of the system.
    Sirotnak FM, Moccio DM, Yang CH.
    J Biol Chem; 1984 Nov 10; 259(21):13139-44. PubMed ID: 6490649
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  • 2. Further studies on a novel class of genetic variants of the L1210 cell with increased folate analogue transport inward. Transport properties of a new variant, evidence for increased levels of a specific transport protein, and its partial characterization following affinity labeling.
    Yang CH, Sirotnak FM, Mines LS.
    J Biol Chem; 1988 Jul 15; 263(20):9703-9. PubMed ID: 2838477
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  • 3. Membrane protein changes in an L1210 leukemia cell line with a translocation defect in the methotrexate-tetrahydrofolate cofactor transport carrier.
    Schuetz JD, Westin EH, Matherly LH, Pincus R, Swerdlow PS, Goldman ID.
    J Biol Chem; 1989 Sep 25; 264(27):16261-7. PubMed ID: 2777791
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  • 7. Carrier-mediated transport of folate compounds in L1210 cells. Initial rate kinetics and extent of duality of entry routes for folic acid and diastereomers of 5-methyltetrahydrohomofolate in the presence of physiological anions.
    Sirotnak FM, Goutas LJ, Jacobsen DM, Mines LS, Barrueco JR, Gaumont Y, Kisliuk RL.
    Biochem Pharmacol; 1987 May 15; 36(10):1659-67. PubMed ID: 3593392
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  • 8. Characterization of the individual transport routes that mediate the influx and efflux of methotrexate in CCRF-CEM human lymphoblastic cells.
    Henderson GB, Tsuji JM, Kumar HP.
    Cancer Res; 1986 Apr 15; 46(4 Pt 1):1633-8. PubMed ID: 3948152
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  • 9. Photoaffinity analogues of methotrexate as folate antagonist binding probes. 2. Transport studies, photoaffinity labeling, and identification of the membrane carrier protein for methotrexate from murine L1210 cells.
    Price EM, Freisheim JH.
    Biochemistry; 1987 Jul 28; 26(15):4757-63. PubMed ID: 3663624
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  • 10. Alteration of folate analogue transport inward after induced maturation of HL-60 leukemia cells. Molecular properties of the transporter in an overproducing variant and evidence for down-regulation of its synthesis in maturating cells.
    Yang CH, Pain J, Sirotnak FM.
    J Biol Chem; 1992 Apr 05; 267(10):6628-34. PubMed ID: 1551871
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  • 11. Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier.
    Zhao R, Gao F, Goldman ID.
    Biochem Pharmacol; 1999 Nov 15; 58(10):1615-24. PubMed ID: 10535753
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  • 12. Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells.
    Spinella MJ, Brigle KE, Sierra EE, Goldman ID.
    J Biol Chem; 1995 Apr 07; 270(14):7842-9. PubMed ID: 7713875
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  • 15. A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function.
    Zhao R, Assaraf YG, Goldman ID.
    J Biol Chem; 1998 Jul 24; 273(30):19065-71. PubMed ID: 9668089
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  • 16. Relationships between carrier-mediated transport of folate compounds by L1210 leukemia cells: evidence for multiplicity of entry routes with different kinetic properties expressed in plasma membrane vesicles.
    Yang CH, Dembo M, Sirotnak FM.
    J Membr Biol; 1983 Jul 24; 75(1):11-20. PubMed ID: 6887234
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  • 17. Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line.
    Brigle KE, Spinella MJ, Sierra EE, Goldman ID.
    J Biol Chem; 1995 Sep 29; 270(39):22974-9. PubMed ID: 7559435
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  • 18. Evidence for a functional defect in the translocation of the methotrexate transport carrier in a methotrexate-resistant murine L1210 leukemia cell line.
    Schuetz JD, Matherly LH, Westin EH, Goldman ID.
    J Biol Chem; 1988 Jul 15; 263(20):9840-7. PubMed ID: 2838483
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  • 20. Characterization of folate transport mediated by a low pH route in mouse L1210 leukemia cells with defective reduced folate carrier function.
    Sierra EE, Goldman ID.
    Biochem Pharmacol; 1998 May 01; 55(9):1505-12. PubMed ID: 10076544
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