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119 related items for PubMed ID: 6506768

  • 1. Glutathione transferase-mediated and non-enzymatic activation and detoxication of the N-hydroxy derivative of Trp-P-2, a potent pyrolysate promutagen.
    Saito K, Yamazoe Y, Kamataki T, Kato R.
    Xenobiotica; 1984 Jul; 14(7):545-8. PubMed ID: 6506768
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  • 3. Catalysis of the covalent binding of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole to DNA by a L-proline- and adenosine triphosphate-dependent enzyme in rat hepatic cytosol.
    Yamazoe Y, Shimada M, Shinohara A, Saito K, Kamataki T, Kato R.
    Cancer Res; 1985 Jun; 45(6):2495-500. PubMed ID: 3986789
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  • 4. Structural elucidation of a mutagenic metabolite of 3-amino-1-methyl-5H-pyrido[4,3-b]indole.
    Yamazoe Y, Ishii K, Kamataki T, Kato R.
    Drug Metab Dispos; 1981 Jun; 9(3):292-6. PubMed ID: 6113943
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  • 5. DNA strand cleavage in vitro by 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]-indole, a direct-acting mutagen formed in the metabolism of carcinogenic 3-amino-1-methyl-5H-pyrido[4,3-b]indole.
    Wakata A, Oka N, Hiramoto K, Yoshioka A, Negishi K, Wataya Y, Hayatsu H.
    Cancer Res; 1985 Nov; 45(11 Pt 2):5867-71. PubMed ID: 4053057
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  • 6. Evidence for the involvement of N-hydroxylation of 3-amino-1-methyl-5H-pyrido[4,3-b]indole by cytochrome P-450 in the covalent binding to DNA.
    Mita S, Ishii K, Yamazoe Y, Kamataki T, Kato R, Sugimura T.
    Cancer Res; 1981 Sep; 41(9 Pt 1):3610-4. PubMed ID: 7020934
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  • 11. Acetyl coenzyme A dependent activation of N-hydroxy derivatives of carcinogenic arylamines: mechanism of activation, species difference, tissue distribution, and acetyl donor specificity.
    Shinohara A, Saito K, Yamazoe Y, Kamataki T, Kato R.
    Cancer Res; 1986 Sep; 46(9):4362-7. PubMed ID: 3731093
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  • 12. N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
    Frandsen H, Alexander J.
    Carcinogenesis; 2000 Jun; 21(6):1197-203. PubMed ID: 10837010
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  • 13. Glutathione transferase theta 1-1-dependent metabolism of the water disinfection byproduct bromodichloromethane.
    Ross MK, Pegram RA.
    Chem Res Toxicol; 2003 Feb; 16(2):216-26. PubMed ID: 12588193
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  • 14. Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAalphaC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes.
    Glatt H, Pabel U, Meinl W, Frederiksen H, Frandsen H, Muckel E.
    Carcinogenesis; 2004 May; 25(5):801-7. PubMed ID: 14729582
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  • 15. Metabolic activation of mutagenic tryptophan pyrolysis products by rat liver microsomes.
    Ishii K, Yamazoe Y, Kamataki T, Kato R.
    Cancer Res; 1980 Jul; 40(7):2596-600. PubMed ID: 6771001
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  • 16. Activation and inactivation of carcinogenic dihaloalkanes and other compounds by glutathione S-transferase 5-5 in Salmonella typhimurium tester strain NM5004.
    Shimada T, Yamazaki H, Oda Y, Hiratsuka A, Watabe T, Guengerich FP.
    Chem Res Toxicol; 1996 Jul; 9(1):333-40. PubMed ID: 8924613
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  • 17. Syntheses of hydroxyamino, nitroso and nitro derivatives of Trp-P-2 and Glu-P-1, amino acid pyrolysate mutagens, and their direct mutagenicities towards Salmonella typhimurium TA98 and TA98NR.
    Saito K, Yamazoe Y, Kamataki T, Kato R.
    Carcinogenesis; 1983 Dec; 4(12):1547-50. PubMed ID: 6360404
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  • 18. Metabolic activation of 3-amino-5H-pyrido[4,3-b]indole, a highly mutagenic principle in tryptophan pyrolysate, by rat liver enzymes.
    Nemoto N, Kusumi S, Takayama S, Nagao M, Sugimura T.
    Chem Biol Interact; 1979 Oct; 27(2-3):191-8. PubMed ID: 498354
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  • 20. Involvement of reactive oxygen species in the immunosuppressive effect of 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1), a food-born carcinogenic heterocyclic amine.
    Yun CH, Chung DK, Yoon K, Han SH.
    Toxicol Lett; 2006 Jun 20; 164(1):37-43. PubMed ID: 16386858
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