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Journal Abstract Search


124 related items for PubMed ID: 6531792

  • 1. Pharmacokinetics of nitrosoureas: comparison of 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) after oral and intravenous administration to rats.
    Russo RG, Cattaneo MT, Bartosek I.
    Tumori; 1984 Dec 31; 70(6):499-502. PubMed ID: 6531792
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  • 2. Relationship of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) pharmacokinetics of uptake, distribution, and tissue/plasma partitioning in rat organs and intracerebral tumors.
    Levin VA, Kabra PA, Freeman-Dove MA.
    Cancer Chemother Pharmacol; 1978 Dec 31; 1(4):233-42. PubMed ID: 750110
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  • 3. The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma pharmacokinetics and biotransformation of BCNU.
    Levin VA, Stearns J, Byrd A, Finn A, Weinkam RJ.
    J Pharmacol Exp Ther; 1979 Jan 31; 208(1):1-6. PubMed ID: 759602
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  • 4. Pharmacokinetics of nitrosoureas: levels of 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) in organs of normal and Walker 256/B carcinoma bearing rats after i.v. bolus.
    Bartosek I, Russo RG, Cattaneo MT.
    Tumori; 1984 Dec 31; 70(6):491-8. PubMed ID: 6531791
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  • 5. Mechanism of uptake of nitrosoureas by L5178Y lymphoblasts in vitro.
    Begleiter A, Lam HP, Goldenberg GJ.
    Cancer Res; 1977 Apr 31; 37(4):1022-7. PubMed ID: 557367
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  • 6. Metabolism of 1,3-bis(2-chloroethyl)-1-nitrosourea by rat hepatic microsomes.
    Lin HS, Weinkam RJ.
    J Med Chem; 1981 Jun 31; 24(6):761-3. PubMed ID: 7252986
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  • 7. Capillary gas chromatography and thermionic N-P-specific detection of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) or 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in stability and pharmacokinetic studies.
    El-Yazigi A, Martin CR.
    Pharm Res; 1988 Apr 31; 5(4):220-5. PubMed ID: 3247301
    [Abstract] [Full Text] [Related]

  • 8. Chemosensitization of the nitrosoureas by 2-nitroimidazoles in the subcutaneous 9L tumor model: pharmacokinetic and structure-activity considerations.
    Wong KH, Wallen CA, Wheeler KT.
    Int J Radiat Oncol Biol Phys; 1990 May 31; 18(5):1043-50. PubMed ID: 2140824
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  • 12. Mechanism of action of (2-haloethyl)nitrosoureas on DNA. Isolation and reactions of postulated 2-(alkylimino)-3-nitrosooxazolidine intermediates in the decomposition of 1,3-bis(2-chloroethyl)-, 1-(2-chloroethyl)-3-cyclohexyl-, and 1-(2-chloroethyl)-3-(4'-trans-methylcyclohexyl)-1-nitrosourea.
    Lown JW, Chauhan SM.
    J Med Chem; 1981 Mar 31; 24(3):270-9. PubMed ID: 7265113
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  • 15. In vivo chemosensitization by misonidazole in sensitive and resistant tumor lines.
    Mulcahy RT, Siemann DW.
    Cancer Res; 1983 Oct 31; 43(10):4709-13. PubMed ID: 6883329
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  • 16. Microsomal metabolism of nitrosoureas.
    Hill DL, Kirk MC, Struck RF.
    Cancer Res; 1975 Feb 31; 35(2):296-301. PubMed ID: 234031
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  • 18. Stereoselective monooxygenation of carcinostatic 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea by purified cytochrome P-450 isozymes.
    Potter DW, Levin W, Ryan DE, Thomas PE, Reed DJ.
    Biochem Pharmacol; 1984 Feb 15; 33(4):609-13. PubMed ID: 6704177
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