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Journal Abstract Search

170 related items for PubMed ID: 6540852

  • 21. Isolation and characterization of a dihydrofolate reductase gene mutation in methotrexate-resistant Drosophila cells.
    Hao H, Tyshenko MG, Walker VK.
    Gene Expr; 1996; 6(4):231-9. PubMed ID: 9196078
    [Abstract] [Full Text] [Related]

  • 22. In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
    van der Laan BF, Jansen G, Kathmann GA, Westerhof GR, Schornagel JH, Hordijk GJ.
    Int J Cancer; 1992 Jul 30; 51(6):909-14. PubMed ID: 1639538
    [Abstract] [Full Text] [Related]

  • 23. New approaches to Leishmania chemotherapy: pteridine reductase 1 (PTR1) as a target and modulator of antifolate sensitivity.
    Nare B, Luba J, Hardy LW, Beverley S.
    Parasitology; 1997 Jul 30; 114 Suppl():S101-10. PubMed ID: 9309772
    [Abstract] [Full Text] [Related]

  • 24. Selection for methotrexate resistance in mammalian cells bearing a Drosophila dihydrofolate reductase transgene: Methotrexate resistance in transgenic mammalian cells.
    Affleck JG, Nowickyj SM, Walker VK.
    Cell Biol Toxicol; 2010 Apr 30; 26(2):117-26. PubMed ID: 19337845
    [Abstract] [Full Text] [Related]

  • 25. Non-glutamate type pyrrolo[2,3-d]pyrimidine antifolates. II. Synthesis and antitumor activity of N5-substituted glutamine analogs.
    Itoh F, Yoshioka Y, Yukishige K, Yoshida S, Wajima M, Ootsu K, Akimoto H.
    Chem Pharm Bull (Tokyo); 1996 Aug 30; 44(8):1498-509. PubMed ID: 8795269
    [Abstract] [Full Text] [Related]

  • 26. Allelic variation in the dihydrofolate reductase gene at amino acid position 95 contributes to antifolate resistance in Chinese hamster cells.
    Yu M, Melera PW.
    Cancer Res; 1993 Dec 15; 53(24):6031-5. PubMed ID: 8261418
    [Abstract] [Full Text] [Related]

  • 27. N10-propargyl-5,8-dideazafolic acid (CB3717): inhibitory effects on human leukemia cell lines resistant to methotrexate or trimetrexate.
    Takemura Y, Ohnuma T.
    Mt Sinai J Med; 1992 Oct 15; 59(5):419-24. PubMed ID: 1435841
    [Abstract] [Full Text] [Related]

  • 28. Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application.
    McIvor RS.
    Bone Marrow Transplant; 1996 Dec 15; 18 Suppl 3():S50-4. PubMed ID: 8971409
    [Abstract] [Full Text] [Related]

  • 29. Novel 6-5 fused ring heterocycle antifolates with potent antitumor activity: bridge modifications and heterocyclic benzoyl isosters of 2,4-diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine antifolate.
    Kotake Y, Okauchi T, Iijima A, Yoshimatsu K, Nomura H.
    Chem Pharm Bull (Tokyo); 1995 May 15; 43(5):829-41. PubMed ID: 7553969
    [Abstract] [Full Text] [Related]

  • 30. In vitro screening of biochemical activity of folic acid antagonists in skin.
    McCullough JL, Weinstein GD, Hynes JB.
    J Invest Dermatol; 1977 Jun 15; 68(6):362-5. PubMed ID: 864277
    [Abstract] [Full Text] [Related]

  • 31. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
    Chello PL, McQueen CA, DeAngelis LM, Bertino JR.
    Cancer Res; 1976 Jul 15; 36(7 PT 1):2442-9. PubMed ID: 1277151
    [Abstract] [Full Text] [Related]

  • 32. Quantitative structure-activity relationship of antifolate inhibition of bacteria cell cultures resistant and sensitive to methotrexate.
    Coats EA, Genther CS, Selassie CD, Strong CD, Hansch C.
    J Med Chem; 1985 Dec 15; 28(12):1910-6. PubMed ID: 3934385
    [Abstract] [Full Text] [Related]

  • 33. Changes in enzyme activity and expression of DHFR of Toxoplasma gondii by antifolates.
    Baek EJ, Nam HW.
    Korean J Parasitol; 1998 Sep 15; 36(3):191-8. PubMed ID: 9755590
    [Abstract] [Full Text] [Related]

  • 34. Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    Rhee MS, Galivan J, Wright JE, Rosowsky A.
    Mol Pharmacol; 1994 Apr 15; 45(4):783-91. PubMed ID: 7514264
    [Abstract] [Full Text] [Related]

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  • 36. Protection of CCRF-CEM human lymphoid cells from antifolates by retroviral gene transfer of variants of murine dihydrofolate reductase.
    Mareya SM, Sorrentino BP, Blakley RL.
    Cancer Gene Ther; 1998 Apr 15; 5(4):225-35. PubMed ID: 9694074
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  • 38. Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors.
    Salem IM, Mostafa SM, Salama I, El-Sabbagh OI, Hegazy WAH, Ibrahim TS.
    J Enzyme Inhib Med Chem; 2023 Dec 15; 38(1):203-215. PubMed ID: 36382444
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