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Journal Abstract Search

101 related items for PubMed ID: 6547937

  • 1. Photosensitive interaction of RSU 1069 with DNA.
    Edwards DI, Knox RJ, Skolimowski IM, Zahoor A, Knight RC.
    Int J Radiat Oncol Biol Phys; 1984 Aug; 10(8):1319-22. PubMed ID: 6547937
    [Abstract] [Full Text] [Related]

  • 2. Induction of DNA strand breaks by RSU-1069, a nitroimidazole-aziridine radiosensitizer. Role of binding of both unreduced and radiation-reduced forms to DNA, in vitro.
    Silver AR, O'Neill P, Jenkins TC.
    Biochem Pharmacol; 1985 Oct 01; 34(19):3537-42. PubMed ID: 3902026
    [Abstract] [Full Text] [Related]

  • 3. Comparative DNA damage induced by nitroimidazole-aziridine drugs: 1. Effects of methyl substitution on drug action.
    Dale LD, Tocher JH, Edwards DI.
    Anticancer Drug Des; 1988 Dec 01; 3(3):169-75. PubMed ID: 3207464
    [Abstract] [Full Text] [Related]

  • 4. Induction of DNA crosslinks in vitro upon reduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131.
    O'Neill P, McNeil SS, Jenkins TC.
    Biochem Pharmacol; 1987 Jun 01; 36(11):1787-92. PubMed ID: 3579973
    [Abstract] [Full Text] [Related]

  • 5. The phosphate-group of DNA as a potential target for RSU-1069, a nitroimidazole-aziridine radiosensitizer.
    Silver AR, O'Neill P, Jenkins TC, McNeil SS.
    Int J Radiat Oncol Biol Phys; 1986 Jul 01; 12(7):1203-6. PubMed ID: 3755715
    [Abstract] [Full Text] [Related]

  • 6. Enhancement of DNA damage in mammalian cells upon bioreduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131.
    Jenner TJ, Sapora O, O'Neill P, Fielden EM.
    Biochem Pharmacol; 1988 Oct 15; 37(20):3837-42. PubMed ID: 3190731
    [Abstract] [Full Text] [Related]

  • 7. The differential cytotoxicity of RSU 1069: cell survival studies indicating interaction with DNA as a possible mode of action.
    Stratford IJ, Walling JM, Silver AR.
    Br J Cancer; 1986 Mar 15; 53(3):339-44. PubMed ID: 3754453
    [Abstract] [Full Text] [Related]

  • 8. Pharmacology of the mixed-function radio- and chemosensitizers CB 1954 and RSU 1069.
    Workman P, Walton MI.
    Int J Radiat Oncol Biol Phys; 1984 Aug 15; 10(8):1307-10. PubMed ID: 6547936
    [Abstract] [Full Text] [Related]

  • 9. The repair of DNA damage induced in V79 mammalian cells by the nitroimidazole-aziridine, RSU-1069. Implications for radiosensitization.
    Jenner TJ, O'Neill P, Crump PW, Fielden EM, Sapora O, Santodonato L.
    Biochem Pharmacol; 1991 Oct 09; 42(9):1705-10. PubMed ID: 1930296
    [Abstract] [Full Text] [Related]

  • 10. Comparative DNA damage and repair induced by misonidazole, CB 1954 and RSU 1069.
    Dale LD, Widdick DA, Edwards DI, Biol GI.
    Int J Radiat Oncol Biol Phys; 1989 Apr 09; 16(4):995-9. PubMed ID: 2649469
    [Abstract] [Full Text] [Related]

  • 11. Interaction of RSU 1069 and 1137 with DNA in vitro. Biological implications and mechanistic aspects.
    Lafleur MV, Westmijze EJ, Visser OJ, Wagenaar N, Soetekouw R, Loman H, Retèl J.
    Biochem Pharmacol; 1991 Jun 01; 41(11):1649-55. PubMed ID: 1828345
    [Abstract] [Full Text] [Related]

  • 12. Assessment of the repair and damage of DNA induced by parent and reduced RSU-1069, a 2-nitroimidazole-aziridine.
    O'Neill P, Cunniffe SM.
    Int J Radiat Oncol Biol Phys; 1989 Apr 01; 16(4):963-6. PubMed ID: 2649467
    [Abstract] [Full Text] [Related]

  • 13. Mechanism of oncogenicity for bioreductive drugs.
    Hei TK, Piao CQ, He ZY, Hall EJ.
    Int J Radiat Oncol Biol Phys; 1992 Apr 01; 22(4):747-50. PubMed ID: 1544847
    [Abstract] [Full Text] [Related]

  • 14. RSU 1069, a 2-nitroimidazole containing an alkylating group: high efficiency as a radio- and chemosensitizer in vitro and in vivo.
    Adams GE, Ahmed I, Sheldon PW, Stratford IJ.
    Int J Radiat Oncol Biol Phys; 1984 Sep 01; 10(9):1653-6. PubMed ID: 6548211
    [Abstract] [Full Text] [Related]

  • 15. Inactivation and repair of double-stranded DNA damaged by the aziridinyl nitroimidazole RSU 1069.
    Lafleur MV, Westmijze EJ, Visser OJ, Wagenaar N, Soetekouw R, Loman H, Retel J.
    Chem Biol Interact; 1992 Mar 01; 82(1):55-71. PubMed ID: 1532139
    [Abstract] [Full Text] [Related]

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  • 17. A new class of analogues of the bifunctional radiosensitizer alpha-(1-aziridinylmethyl)-2-nitro-1H-imidazole-1-ethanol (RSU 1069): the cycloalkylaziridines.
    Suto MJ, Stier MA, Werbel LM, Arundel-Suto CM, Leopold WR, Elliott WE, Sebolt-Leopold JS.
    J Med Chem; 1991 Aug 01; 34(8):2484-8. PubMed ID: 1875345
    [Abstract] [Full Text] [Related]

  • 18. DNA strand scission and cross-linking by diaziridinylbenzoquinone (diaziquone) in human cells and relation to cell killing.
    Szmigiero L, Erickson LC, Ewig RA, Kohn KW.
    Cancer Res; 1984 Oct 01; 44(10):4447-52. PubMed ID: 6467204
    [Abstract] [Full Text] [Related]

  • 19. Dual-function 2-nitroimidazoles as hypoxic cell radiosensitizers and bioreductive cytotoxins: in vivo evaluation in KHT murine sarcomas.
    Cole S, Stratford IJ, Adams GE, Fielden EM, Jenkins TC.
    Radiat Res; 1990 Oct 01; 124(1 Suppl):S38-43. PubMed ID: 2236508
    [Abstract] [Full Text] [Related]

  • 20. Studies with bifunctional bioreductive drugs. I. In vitro oncogenic transforming potential.
    Hei TK, He ZY, Piao CQ, Hall EJ.
    Radiat Res; 1990 Oct 01; 124(1 Suppl):S44-9. PubMed ID: 2236509
    [Abstract] [Full Text] [Related]

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