These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Stimulation of methotrexate resistance and dihydrofolate reductase gene amplification by c-myc. Denis N, Kitzis A, Kruh J, Dautry F, Corcos D. Oncogene; 1991 Aug; 6(8):1453-7. PubMed ID: 1886715 [Abstract] [Full Text] [Related]
5. Selective killing of methotrexate-resistant cells carrying amplified dihydrofolate reductase genes. Urlaub G, Landzberg M, Chasin LA. Cancer Res; 1981 May; 41(5):1594-601. PubMed ID: 7194140 [Abstract] [Full Text] [Related]
6. Mitogenic hormones and tumor promoters greatly increase the incidence of colony-forming cells bearing amplified dihydrofolate reductase genes. Barsoum J, Varshavsky A. Proc Natl Acad Sci U S A; 1983 Sep; 80(17):5330-4. PubMed ID: 6351057 [Abstract] [Full Text] [Related]
7. Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations. Hill AB, Schimke RT. Cancer Res; 1985 Oct; 45(10):5050-7. PubMed ID: 4027984 [Abstract] [Full Text] [Related]
8. [Mice transduced with double-mutant dihydrofolate reductase-cytidine deaminase fusion gene attained protection from high dose chemotherapy]. Lu P, Lu Y, Pang K, Wang SB, Chen JQ, Xu HM, Wang JK, Zhao SC. Zhonghua Wai Ke Za Zhi; 2005 Aug 01; 43(15):998-1001. PubMed ID: 16194358 [Abstract] [Full Text] [Related]
9. Molecular and karyological analysis of methotrexate-resistant and -sensitive human leukemic CCRF-CEM cells. Mini E, Srimatkandada S, Medina WD, Moroson BA, Carman MD, Bertino JR. Cancer Res; 1985 Jan 01; 45(1):317-24. PubMed ID: 3855283 [Abstract] [Full Text] [Related]
10. Acquisition and loss of amplified genes: dramatic effects of hormones, tumor promoters and cytotoxic drugs. Varshavsky A, Barsoum J, Roninson I, Snapka R. Princess Takamatsu Symp; 1983 Jan 01; 14():235-54. PubMed ID: 6394591 [Abstract] [Full Text] [Related]
11. Increasing methotrexate resistance by combination of active-site mutations in human dihydrofolate reductase. Volpato JP, Fossati E, Pelletier JN. J Mol Biol; 2007 Oct 26; 373(3):599-611. PubMed ID: 17868689 [Abstract] [Full Text] [Related]
12. [Amplification of portions of the genome in the somatic cells of mammals resistant to colchicine. V. The induction of gene amplification in the cells of the Djungarian hamster and the mouse]. Kopnin BP, Gudkov AV. Genetika; 1983 Jun 26; 19(6):872-80. PubMed ID: 6684074 [Abstract] [Full Text] [Related]
13. UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells. Tlsty TD, Brown PC, Schimke RT. Mol Cell Biol; 1984 Jun 26; 4(6):1050-6. PubMed ID: 6738530 [Abstract] [Full Text] [Related]
14. Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea. Brown PC, Tlsty TD, Schimke RT. Mol Cell Biol; 1983 Jun 26; 3(6):1097-107. PubMed ID: 6877240 [Abstract] [Full Text] [Related]
15. Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene. Takebe N, Zhao SC, Adhikari D, Mineishi S, Sadelain M, Hilton J, Colvin M, Banerjee D, Bertino JR. Mol Ther; 2001 Jan 26; 3(1):88-96. PubMed ID: 11162315 [Abstract] [Full Text] [Related]
16. Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells. 1978. Alt FW, Kellems RE, Bertino JR, Schimke RT. Biotechnology; 1992 Jan 26; 24():397-410. PubMed ID: 1422048 [No Abstract] [Full Text] [Related]
18. Methotrexate accumulates to similar levels in animals transplanted with normal versus drug-resistant transgenic marrow. Belur LR, Boelk-Galvan D, Diers MD, McIvor RS, Zimmerman CL. Cancer Res; 2001 Feb 15; 61(4):1522-6. PubMed ID: 11245460 [Abstract] [Full Text] [Related]
19. Plasmodium falciparum: gene mutations and amplification of dihydrofolate reductase genes in parasites grown in vitro in presence of pyrimethamine. Thaithong S, Ranford-Cartwright LC, Siripoon N, Harnyuttanakorn P, Kanchanakhan NS, Seugorn A, Rungsihirunrat K, Cravo PV, Beale GH. Exp Parasitol; 2001 Jun 15; 98(2):59-70. PubMed ID: 11465989 [Abstract] [Full Text] [Related]
20. Rates of development of methotrexate resistance in heterogeneous mouse mammary tumor cell cultures. Miller BE, Matherly LH, Lehotan M, Heppner GH. J Exp Ther Oncol; 1996 Jan 15; 1(1):30-8. PubMed ID: 9414386 [Abstract] [Full Text] [Related] Page: [Next] [New Search]