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Journal Abstract Search

129 related items for PubMed ID: 6787199

  • 1. Methotrexate analogues. 13. Chemical and pharmacological studies on amide, hydrazide, and hydroxamic acid derivatives of the glutamate side chain.
    Rosowsky A, Yu CS, Uren J, Lazarus H, Wick M.
    J Med Chem; 1981 May; 24(5):559-67. PubMed ID: 6787199
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  • 2. Methotrexate analogues. 28. Synthesis and biological evaluation of new gamma-monoamides of aminopterin and methotrexate.
    Rosowsky A, Bader H, Radike-Smith M, Cucchi CA, Wick MM, Freisheim JH.
    J Med Chem; 1986 Sep; 29(9):1703-9. PubMed ID: 3462394
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  • 3. Methotrexate analogues. 34. Replacement of the glutamate moiety in methotrexate and aminopterin by long-chain 2-aminoalkanedioic acids.
    Rosowsky A, Bader H, Kohler W, Freisheim JH, Moran RG.
    J Med Chem; 1988 Jul; 31(7):1338-44. PubMed ID: 2898531
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  • 4. Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chain.
    Rosowsky A, Freisheim JH, Moran RG, Solan VC, Bader H, Wright JE, Radike-Smith M.
    J Med Chem; 1986 May; 29(5):655-60. PubMed ID: 2871191
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  • 5. Methotrexate analogues. 33. N delta-acyl-N alpha-(4-amino-4-deoxypteroyl)-L-ornithine derivatives: synthesis and in vitro antitumor activity.
    Rosowsky A, Bader H, Cucchi CA, Moran RG, Kohler W, Freisheim JH.
    J Med Chem; 1988 Jul; 31(7):1332-7. PubMed ID: 3385730
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  • 6. Methotrexate analogues. 14. Synthesis of new gamma-substituted derivatives as dihydrofolate reductase inhibitors and potential anticancer agents.
    Rosowsky A, Forsch R, Uren J, Wick M.
    J Med Chem; 1981 Dec; 24(12):1450-5. PubMed ID: 6796689
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  • 7. Methotrexate analogues. 19. Replacement of the glutamate side chain in classical antifolates by L-homocysteic acid and L-cysteic acid: effect on enzyme inhibition and antitumor activity.
    Rosowsky A, Forsch RA, Freisheim JH, Moran RG, Wick M.
    J Med Chem; 1984 May; 27(5):600-4. PubMed ID: 6546949
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  • 12. Syntheses and antifolate activity of 5-methyl-5-deaza analogues of aminopterin, methotrexate, folic acid, and N10-methylfolic acid.
    Piper JR, McCaleb GS, Montgomery JA, Kisliuk RL, Gaumont Y, Sirotnak FM.
    J Med Chem; 1986 Jun; 29(6):1080-7. PubMed ID: 2423690
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  • 13. Methotrexate analogues-27. Dual inhibition of dihydrofolate reductase and folylpolyglutamate synthetase by methotrexate and aminopterin analogues with a gamma-phosphonate group in the side chain.
    Rosowsky A, Moran RC, Forsch RA, Radike-Smith M, Colman PD, Wick MM, Freisheim JH.
    Biochem Pharmacol; 1986 Oct 01; 35(19):3327-33. PubMed ID: 3768024
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  • 14. Methotrexate analogs. 6. Replacement of glutamic acid by various amino acid esters and amines.
    Chaykovsky M, Brown BL, Modest EJ.
    J Med Chem; 1975 Sep 01; 18(9):909-12. PubMed ID: 808614
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  • 18. Methotrexate analogues. 23. Synthesis, dihydrofolate reductase affinity, cytotoxicity, and in vivo antitumor activity of some putative degradation products of methotrexate-poly(L-lysine) conjugates.
    Rosowsky A, Forsch RA, Freisheim JH, Galivan J, Wick M.
    J Med Chem; 1984 Jul 01; 27(7):888-93. PubMed ID: 6737432
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  • 19. Occurrence and significance of diastereomers of methotrexate alpha-peptides.
    Kuefner U, Esswein A, Lohrmann U, Montejano Y, Vitols KS, Huennekens FM.
    Biochemistry; 1990 Nov 20; 29(46):10540-5. PubMed ID: 2271663
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