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Journal Abstract Search

361 related items for PubMed ID: 6825087

  • 1. Metabolism of trichloroethylene in isolated hepatocytes, microsomes, and reconstituted enzyme systems containing cytochrome P-450.
    Miller RE, Guengerich FP.
    Cancer Res; 1983 Mar; 43(3):1145-52. PubMed ID: 6825087
    [Abstract] [Full Text] [Related]

  • 2. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [Abstract] [Full Text] [Related]

  • 3. Roles of 2-haloethylene oxides and 2-haloacetaldehydes derived from vinyl bromide and vinyl chloride in irreversible binding to protein and DNA.
    Guengerich FP, Mason PS, Stott WT, Fox TR, Watanabe PG.
    Cancer Res; 1981 Nov; 41(11 Pt 1):4391-8. PubMed ID: 7030476
    [Abstract] [Full Text] [Related]

  • 4. Covalent interaction of metabolites of the carcinogen trichloroethylene in rat hepatic microsomes.
    Van Duuren BL, Banerjee S.
    Cancer Res; 1976 Jul; 36(7 PT 1):2419-22. PubMed ID: 1277148
    [Abstract] [Full Text] [Related]

  • 5. Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes.
    Elfarra AA, Krause RJ, Last AR, Lash LH, Parker JC.
    Drug Metab Dispos; 1998 Aug; 26(8):779-85. PubMed ID: 9698293
    [Abstract] [Full Text] [Related]

  • 6. Hepatic and pulmonary microsomal metabolism of naphthalene to glutathione adducts: factors affecting the relative rates of conjugate formation.
    Buckpitt AR, Bahnson LS, Franklin RB.
    J Pharmacol Exp Ther; 1984 Nov; 231(2):291-300. PubMed ID: 6491983
    [Abstract] [Full Text] [Related]

  • 7. Covalent binding of the carcinogen trichloroethylene to hepatic microsomal proteins and to exogenous DNA in vitro.
    Banerjee S, Van Duuren BL.
    Cancer Res; 1978 Mar; 38(3):776-80. PubMed ID: 626981
    [Abstract] [Full Text] [Related]

  • 8. Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1.
    Forkert PG, Baldwin RM, Millen B, Lash LH, Putt DA, Shultz MA, Collins KS.
    Drug Metab Dispos; 2005 Oct; 33(10):1429-37. PubMed ID: 15987776
    [Abstract] [Full Text] [Related]

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  • 10. In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis.
    Saghir SA, Zhang F, Rick DL, Kan L, Bus JS, Bartels MJ.
    Regul Toxicol Pharmacol; 2010 Oct; 57(2-3):129-35. PubMed ID: 20096743
    [Abstract] [Full Text] [Related]

  • 11. Glutathione conjugation of trichloroethylene in human liver and kidney: kinetics and individual variation.
    Lash LH, Lipscomb JC, Putt DA, Parker JC.
    Drug Metab Dispos; 1999 Mar; 27(3):351-9. PubMed ID: 10064565
    [Abstract] [Full Text] [Related]

  • 12. Pulmonary bronchiolar cytotoxicity and formation of dichloroacetyl lysine protein adducts in mice treated with trichloroethylene.
    Forkert PG, Millen B, Lash LH, Putt DA, Ghanayem BI.
    J Pharmacol Exp Ther; 2006 Feb; 316(2):520-9. PubMed ID: 16269531
    [Abstract] [Full Text] [Related]

  • 13. Trichloroethylene. II. Mechanism of carcinogenicity of trichloroethylene.
    Motohashi N, Nagashima H, Molnár J.
    In Vivo; 1999 Feb; 13(3):215-9. PubMed ID: 10459494
    [Abstract] [Full Text] [Related]

  • 14. Glutathione conjugation of trichloroethylene in rats and mice: sex-, species-, and tissue-dependent differences.
    Lash LH, Qian W, Putt DA, Jacobs K, Elfarra AA, Krause RJ, Parker JC.
    Drug Metab Dispos; 1998 Jan; 26(1):12-9. PubMed ID: 9443846
    [Abstract] [Full Text] [Related]

  • 15. Consideration of the target organ toxicity of trichloroethylene in terms of metabolite toxicity and pharmacokinetics.
    Davidson IW, Beliles RP.
    Drug Metab Rev; 1991 Jan; 23(5-6):493-599. PubMed ID: 1802654
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  • 17. Oxidation of trichloroethylene by liver microsomal cytochrome P-450: evidence for chlorine migration in a transition state not involving trichloroethylene oxide.
    Miller RE, Guengerich FP.
    Biochemistry; 1982 Mar 02; 21(5):1090-7. PubMed ID: 7074051
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  • 20. Cytochrome P-450-dependent bioactivation of 1,1-dichloroethylene to a reactive epoxide in human lung and liver microsomes.
    Dowsley TF, Reid K, Petsikas D, Ulreich JB, Fisher RL, Forkert PG.
    J Pharmacol Exp Ther; 1999 May 02; 289(2):641-8. PubMed ID: 10215634
    [Abstract] [Full Text] [Related]

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