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173 related items for PubMed ID: 7049365
1. Ellipticine, 9-hydroxyellipticine, and 9-hydroxyellipiticinum: some biochemical properties of possible pharmacologic significance. Paoletti C, Auclair C, Lesca P, Tocanne JF, Malvy C, Pinto M. Cancer Treat Rep; 1981; 65 Suppl 3():107-18. PubMed ID: 7049365 [Abstract] [Full Text] [Related]
2. The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide. Stiborová M, Sejbal J, Borek-Dohalská L, Aimová D, Poljaková J, Forsterová K, Rupertová M, Wiesner J, Hudecek J, Wiessler M, Frei E. Cancer Res; 2004 Nov 15; 64(22):8374-80. PubMed ID: 15548707 [Abstract] [Full Text] [Related]
3. Effects of ellipticine on cell survival and cell cycle progression in cultured mammalian cells. Traganos F, Staiano-Coico L, Darzynkiewicz Z, Melamed MR. Cancer Res; 1980 Jul 15; 40(7):2390-9. PubMed ID: 6155993 [Abstract] [Full Text] [Related]
4. Cytotoxic effects of the lysosomotropic agents DNA-ellipticine, DNA-daunorubicin, and DNA-ellipticine:daunorubicin on L1210 leukemia cells. Sorace RA, Sheid B. Cancer Treat Rep; 1979 Jan 15; 63(1):43-51. PubMed ID: 421232 [No Abstract] [Full Text] [Related]
5. Cytochrome P450- and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its anti-tumor efficiency. Stiborová M, Rupertová M, Frei E. Biochim Biophys Acta; 2011 Jan 15; 1814(1):175-85. PubMed ID: 20576524 [Abstract] [Full Text] [Related]
8. Oxidation of an antitumor drug ellipticine by peroxidases. Poljaková J, Forsterová K, Sulc M, Frei E, Stiborová M. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub; 2005 Dec 15; 149(2):449-53. PubMed ID: 16601808 [Abstract] [Full Text] [Related]
12. Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine. Stiborová M, Poljaková J, Ryslavá H, Dracínský M, Eckschlager T, Frei E. Int J Cancer; 2007 Jan 15; 120(2):243-51. PubMed ID: 17066455 [Abstract] [Full Text] [Related]
13. [9-Nitro- and 9-amino-ellipticines and derivatives: synthesis and pharmacologic properties]. Gansser C, Viel C, Malvy C, Cros S. Farmaco Sci; 1980 Nov 15; 35(11):887-95. PubMed ID: 7450021 [Abstract] [Full Text] [Related]
14. Cytotoxicity of and DNA adduct formation by ellipticine in human U87MG glioblastoma cancer cells. Martinkova E, Dontenwill M, Frei E, Stiborova M. Neuro Endocrinol Lett; 2009 Nov 15; 30 Suppl 1():60-6. PubMed ID: 20027146 [Abstract] [Full Text] [Related]
15. Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy. Kotrbová V, Mrázová B, Moserová M, Martínek V, Hodek P, Hudeček J, Frei E, Stiborová M. Biochem Pharmacol; 2011 Sep 15; 82(6):669-80. PubMed ID: 21683692 [Abstract] [Full Text] [Related]
17. The mechanism of cytotoxicity and DNA adduct formation by the anticancer drug ellipticine in human neuroblastoma cells. Poljaková J, Eckschlager T, Hrabeta J, Hrebacková J, Smutný S, Frei E, Martínek V, Kizek R, Stiborová M. Biochem Pharmacol; 2009 May 01; 77(9):1466-79. PubMed ID: 19426684 [Abstract] [Full Text] [Related]
18. Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system. Auclair C, Paoletti C. J Med Chem; 1981 Mar 01; 24(3):289-95. PubMed ID: 7265115 [Abstract] [Full Text] [Related]
20. [Syntheses designed to produce 8-amino ellipticine. Synthesis and pharmacological properties of 8-nitro ellipticine]. Gansser C, Lévque X, Plat M, Viel C. Farmaco Sci; 1982 May 01; 37(5):283-97. PubMed ID: 7095141 [Abstract] [Full Text] [Related] Page: [Next] [New Search]