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Journal Abstract Search

103 related items for PubMed ID: 7057420

  • 1. Comparison of quantitative structure-activity relationships of the inhibition of leukemia cells in culture with the inhibition of dihydrofolate reductase from leukemia cells and other cell types.
    Khwaja TA, Pentecost S, Selassie CD, Guo Z, Hansch C.
    J Med Chem; 1982 Feb; 25(2):153-6. PubMed ID: 7057420
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  • 2. A comparison of the inhibition of bovine and murine leukemia dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-X-phenyl)-s-triazines.
    Guo ZR, Dietrich SW, Hansch C, Dolnick BJ, Bertino JR.
    Mol Pharmacol; 1981 Nov; 20(3):649-56. PubMed ID: 7329407
    [No Abstract] [Full Text] [Related]

  • 3. Quantitative structure-activity relationship of triazine-antifolate inhibition of Leishmania dihydrofolate reductase and cell growth.
    Booth RG, Selassie CD, Hansch C, Santi DV.
    J Med Chem; 1987 Jul; 30(7):1218-24. PubMed ID: 3599028
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  • 4. A comparison of the inhibition of growth of methotrexate-resistant and -sensitive leukemia cells in culture by triazines. Evidence for a new mechanism of cell resistance to methotrexate.
    Selassie CD, Guo Z, Hansch C, Khwaja TA, Pentecost S.
    J Med Chem; 1982 Feb; 25(2):157-61. PubMed ID: 7057421
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  • 5. Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
    Selassie CD, Hansch C, Khwaja TA, Dias CB, Pentecost S.
    J Med Chem; 1984 Mar; 27(3):347-57. PubMed ID: 6699880
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  • 6. Comparison of triazines as inhibitors of L1210 dihydrofolate reductase and of L1210 cells sensitive and resistant to methotrexate.
    Selassie CD, Strong CD, Hansch C, Delcamp TJ, Freisheim JH, Khwaja TA.
    Cancer Res; 1986 Feb; 46(2):744-56. PubMed ID: 3940640
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  • 7. [Comparison of inhibitory effects of triazines on dihydrofolate reductase isolated from murine leukemia cells with the inhibition of growth of cells in culture].
    Guo ZG.
    Yao Xue Xue Bao; 1983 Feb; 18(2):125-9. PubMed ID: 6613591
    [No Abstract] [Full Text] [Related]

  • 8. Inhibition of human dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(substituted-phenyl)-s-triazine s. A quantitative structure-activity relationship analysis.
    Hathaway BA, Guo ZR, Hansch C, Delcamp TJ, Susten SS, Freisheim JH.
    J Med Chem; 1984 Feb; 27(2):144-9. PubMed ID: 6694162
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  • 11. Crystallography, quantitative structure-activity relationships, and molecular graphics in a comparative analysis of the inhibition of dihydrofolate reductase from chicken liver and Lactobacillus casei by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(substituted-phenyl)-s-triazine s.
    Hansch C, Hathaway BA, Guo ZR, Selassie CD, Dietrich SW, Blaney JM, Langridge R, Volz KW, Kaufman BT.
    J Med Chem; 1984 Feb; 27(2):129-43. PubMed ID: 6420569
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  • 12. Irreversible enzyme inhibitors. 173. Cure of Walker 256 ascites by reversible and irreversible inhibitors of dihydrofolic reductase derived from 1-(substituted-phenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine.
    Baker BR, Vermeulen NM, Ashton WT, Ryan AJ.
    J Med Chem; 1970 Nov; 13(6):1130-40. PubMed ID: 5479852
    [No Abstract] [Full Text] [Related]

  • 13. Inhibition of dihydrofolate reductase. 3. 4.6-Diamino-1,2-dihydro-2,2-dimethyl-1-(2-substituted-phenyl)-s-triazine inhibition of bovine liver and mouse tumor enzymes.
    Kim KH, Dietrich SW, Hansch C, Dolnick BJ, Bertino JR.
    J Med Chem; 1980 Nov; 23(11):1248-51. PubMed ID: 7452676
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  • 15. Inhibition of a methotrexate-insensitive dihydrofolate reductase from L5178Y cells by substituted triazines and quinazolines.
    Dedhar S, Freisheim JH, Hynes JB, Goldie JH.
    Biochem Pharmacol; 1983 Mar 01; 32(5):922-4. PubMed ID: 6838639
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  • 16. Inhibition of dihydrofolate reductase: structure-activity correlations of 2,4-diamino-5-benzylpyrimidines based upon molecular shape analysis.
    Hopfinger AJ.
    J Med Chem; 1981 Jul 01; 24(7):818-22. PubMed ID: 7277386
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  • 17. Comparison of the inhibition of methotrexate-sensitive and -resistant Lactobacillus casei cell cultures with purified Lactobacillus casei dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-substituted-phenyl)-s-triazines. Use of quantitative structure-activity relationships in making inferences about the mechanism of resistance and the structure of the enzyme is situ compared with the enzyme in vitro.
    Coats EA, Genther CS, Dietrich SW, Guo ZR, Hansch C.
    J Med Chem; 1981 Dec 01; 24(12):1422-9. PubMed ID: 6796688
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  • 18. Inhibition of bovine and rat liver dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(4-substituted-phenyl)-s-triazines.
    Hansch C, Dietrich SW, Fukunaga JY.
    J Med Chem; 1981 May 01; 24(5):544-9. PubMed ID: 7241512
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