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PUBMED FOR HANDHELDS

Journal Abstract Search


103 related items for PubMed ID: 7069722

  • 1. A comparison of the inhibitory action of 5-(substituted-benzyl)-2,4-diaminopyrimidines on dihydrofolate reductase from chicken liver with that from bovine liver.
    Li R, Hansch C, Kaufman BT.
    J Med Chem; 1982 Apr; 25(4):435-40. PubMed ID: 7069722
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  • 3. Quantitative structure-activity relationship of 5-(X-benzyl)-2,4-diaminopyrimidines inhibiting bovine liver dihydrofolate reductase.
    Blaney JM, Dietrich SW, Reynolds MA, Hansch C.
    J Med Chem; 1979 Jun; 22(6):614-7. PubMed ID: 458817
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  • 5. Inhibition of chicken liver dihydrofolate reductase by 5-(substituted benzyl)-2,4-diaminopyrimidines. A quantitative structure-activity relationship and graphics analysis.
    Selassie CD, Fang ZX, Li RL, Hansch C, Klein T, Langridge R, Kaufman BT.
    J Med Chem; 1986 May; 29(5):621-6. PubMed ID: 3701780
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  • 10. On the optimization of hydrophobic and hydrophilic substituent interactions of 2,4-diamino-5-(substituted-benzyl)pyrimidines with dihydrofolate reductase.
    Selassie CD, Li RL, Poe M, Hansch C.
    J Med Chem; 1991 Jan; 34(1):46-54. PubMed ID: 1899453
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  • 12. Synthesis and testing of 5-benzyl-2,4-diaminopyrimidines as potential inhibitors of leishmanial and trypanosomal dihydrofolate reductase.
    Chowdhury SF, Guerrero RH, Brun R, Ruiz-Perez LM, Pacanowska DG, Gilbert IH.
    J Enzyme Inhib Med Chem; 2002 Oct; 17(5):293-302. PubMed ID: 12683746
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  • 17. Inhibition of bovine and rat liver dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(4-substituted-phenyl)-s-triazines.
    Hansch C, Dietrich SW, Fukunaga JY.
    J Med Chem; 1981 May; 24(5):544-9. PubMed ID: 7241512
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  • 18. Irreversible enzyme inhibitors. 198. Diaminodihydro-S-triazines and diaminopyrimidines bearing substituted (ureidomethyl)phenyl substituents as reversible inhibitors of dihydrofolate reductase.
    Ashton WT, Kirk LL, Baker BR.
    J Med Chem; 1973 May; 16(5):453-6. PubMed ID: 4736964
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  • 20. New 2,4-diamino-5-(2',5'-substituted benzyl)pyrimidines as potential drugs against opportunistic infections of AIDS and other immune disorders. Synthesis and species-dependent antifolate activity.
    Rosowsky A, Forsch RA, Sibley CH, Inderlied CB, Queener SF.
    J Med Chem; 2004 Mar 11; 47(6):1475-86. PubMed ID: 14998335
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