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121 related items for PubMed ID: 7123246

  • 1. Penicillin target enzyme and the antibiotic binding site.
    Kelly JA, Moews PC, Knox JR, Frère JM, Ghuysen JM.
    Science; 1982 Oct 29; 218(4571):479-81. PubMed ID: 7123246
    [Abstract] [Full Text] [Related]

  • 2. 2.8-A Structure of penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase from Streptomyces R61 and complexes with beta-lactams.
    Kelly JA, Knox JR, Moews PC, Hite GJ, Bartolone JB, Zhao H, Joris B, Frère JM, Ghuysen JM.
    J Biol Chem; 1985 May 25; 260(10):6449-58. PubMed ID: 3997832
    [Abstract] [Full Text] [Related]

  • 3. Tertiary structural similarity between a class A beta-lactamase and a penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase.
    Samraoui B, Sutton BJ, Todd RJ, Artymiuk PJ, Waley SG, Phillips DC.
    Nature; 1985 May 25; 320(6060):378-80. PubMed ID: 3485771
    [Abstract] [Full Text] [Related]

  • 4. Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases.
    Kuzin AP, Liu H, Kelly JA, Knox JR.
    Biochemistry; 1995 Jul 25; 34(29):9532-40. PubMed ID: 7626623
    [Abstract] [Full Text] [Related]

  • 5. Crystallographic mapping of beta-lactams bound to a D-alanyl-D-alanine peptidase target enzyme.
    Kelly JA, Knox JR, Zhao H, Frère JM, Ghaysen JM.
    J Mol Biol; 1989 Sep 20; 209(2):281-95. PubMed ID: 2585485
    [Abstract] [Full Text] [Related]

  • 6. Mode of interaction between beta-lactam antibiotics and the exocellular DD-carboxypeptidase--transpeptidase from Streptomyces R39.
    Fuad N, Frère JM, Ghuysen JM, Duez C, Iwatsubo M.
    Biochem J; 1976 Jun 01; 155(3):623-9. PubMed ID: 949323
    [Abstract] [Full Text] [Related]

  • 7. Studying enzyme-beta-lactam interactions using X-ray diffraction.
    Kelly JA, Knox JR, Zhao H.
    J Mol Graph; 1989 Jun 01; 7(2):87-92. PubMed ID: 2488268
    [Abstract] [Full Text] [Related]

  • 8. DD-Carboxypeptidase activity of membrane fragments of Mycobacterium smegmatis. Enzymatic properties and sensitivity to beta-lactam antibiotics.
    Eun HM, Yapo A, Petit JF.
    Eur J Biochem; 1978 May 01; 86(1):97-103. PubMed ID: 658048
    [Abstract] [Full Text] [Related]

  • 9. Binding of beta-lactam antibiotics to the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39.
    Frère JM, Ghuysen JM, Reynolds PE, Moreno R.
    Biochem J; 1974 Oct 01; 143(1):241-9. PubMed ID: 4464853
    [Abstract] [Full Text] [Related]

  • 10. Structural aspects for evolution of beta-lactamases from penicillin-binding proteins.
    Meroueh SO, Minasov G, Lee W, Shoichet BK, Mobashery S.
    J Am Chem Soc; 2003 Aug 13; 125(32):9612-8. PubMed ID: 12904027
    [Abstract] [Full Text] [Related]

  • 11. The mechanism of action of penicillin. Penicillin acylates the active site of Bacillus stearothermophilus D-alanine carboxypeptidase.
    Yocum RR, Rasmussen JR, Strominger JL.
    J Biol Chem; 1980 May 10; 255(9):3977-86. PubMed ID: 7372662
    [Abstract] [Full Text] [Related]

  • 12. Penicillins and cephalosporins are active site-directed acylating agents: evidence in support of the substrate analogue hypothesis.
    Waxman DJ, Yocum RR, Strominger JL.
    Philos Trans R Soc Lond B Biol Sci; 1980 May 16; 289(1036):257-71. PubMed ID: 6109322
    [Abstract] [Full Text] [Related]

  • 13. Active-site-serine D-alanyl-D-alanine-cleaving-peptidase-catalysed acyl-transfer reactions. Procedures for studying the penicillin-binding proteins of bacterial plasma membranes.
    Ghuysen JM, Frère JM, Leyh-Bouille M, Nguyen-Distèche M, Coyette J.
    Biochem J; 1986 Apr 01; 235(1):159-65. PubMed ID: 3741376
    [Abstract] [Full Text] [Related]

  • 14. Secondary structure relations between beta-lactamases and penicillin-sensitive D-alanine-carboxypeptidases.
    Moews PC, Knox JR, Waxman DJ, Strominger JL.
    Int J Pept Protein Res; 1981 Feb 01; 17(2):211-8. PubMed ID: 6971815
    [Abstract] [Full Text] [Related]

  • 15. Interaction between monobactams and Streptomyces R61 DD-carboxypeptidase.
    Georgopapadakou NH, Smith SA, Cimarusti CM.
    Eur J Biochem; 1982 Jun 01; 124(3):507-12. PubMed ID: 7106103
    [Abstract] [Full Text] [Related]

  • 16. A 1.2-A snapshot of the final step of bacterial cell wall biosynthesis.
    Lee W, McDonough MA, Kotra L, Li ZH, Silvaggi NR, Takeda Y, Kelly JA, Mobashery S.
    Proc Natl Acad Sci U S A; 2001 Feb 13; 98(4):1427-31. PubMed ID: 11171967
    [Abstract] [Full Text] [Related]

  • 17. The 4.5 A resolution structure analysis of the exocellular DD-carboxypeptidase of Streptomyces albus G.
    Dideberg O, Charlier P, Dupont L, Vermeire M, Frere JM, Ghuysen JM.
    FEBS Lett; 1980 Aug 11; 117(1):212-4. PubMed ID: 7409166
    [No Abstract] [Full Text] [Related]

  • 18. On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target.
    Kelly JA, Dideberg O, Charlier P, Wery JP, Libert M, Moews PC, Knox JR, Duez C, Fraipont C, Joris B.
    Science; 1986 Mar 21; 231(4744):1429-31. PubMed ID: 3082007
    [Abstract] [Full Text] [Related]

  • 19. Penicillin-binding proteins and the mechanism of action of beta-lactam antibiotics.
    Waxman DJ, Strominger JL.
    Annu Rev Biochem; 1983 Mar 21; 52():825-69. PubMed ID: 6351730
    [No Abstract] [Full Text] [Related]

  • 20. Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis.
    Rhazi N, Charlier P, Dehareng D, Engher D, Vermeire M, Frère JM, Nguyen-Distèche M, Fonzé E.
    Biochemistry; 2003 Mar 18; 42(10):2895-906. PubMed ID: 12627955
    [Abstract] [Full Text] [Related]

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