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183 related items for PubMed ID: 7150358

  • 1. Aspartate carbamoyltransferase activity, drug concentrations, and pyrimidine nucleotides in tissue from patients treated with N-(phosphonacetyl)-L-aspartate.
    Moore EC, Friedman J, Valdivieso M, Plunkett W, Marti JR, Russ J, Loo TL.
    Biochem Pharmacol; 1982 Oct 15; 31(20):3317-21. PubMed ID: 7150358
    [Abstract] [Full Text] [Related]

  • 2. N-(Phosphonacetyl)-L-aspartate inhibition of the enzyme complex of pyrimidine biosynthesis.
    Moore EC.
    Biochem Pharmacol; 1982 Oct 15; 31(20):3313-6. PubMed ID: 7150357
    [Abstract] [Full Text] [Related]

  • 3. Overproduction of the first three enzymes of pyrimidine nucleotide biosynthesis in Drosophila cells resistant to N-phosphonacetyl-L-aspartate.
    Laval M, Azou Y, Giorgi D, Rosset R.
    Exp Cell Res; 1986 Apr 15; 163(2):381-95. PubMed ID: 2869965
    [Abstract] [Full Text] [Related]

  • 4. In situ properties of Helicobacter pylori aspartate carbamoyltransferase.
    Burns BP, Mendz GL, Hazell SL.
    Arch Biochem Biophys; 1997 Nov 01; 347(1):119-25. PubMed ID: 9344472
    [Abstract] [Full Text] [Related]

  • 5. Kinetics of N-(phosphonacetyl)-L-aspartate and pyrazofurin depletion of pyrimidine ribonucleotide and deoxyribonucleotide pools and their relationship to nucleic acid synthesis in intact and permeabilized cells.
    Moyer JD, Smith PA, Levy EJ, Handschumacher RE.
    Cancer Res; 1982 Nov 01; 42(11):4525-31. PubMed ID: 7127293
    [Abstract] [Full Text] [Related]

  • 6. A phase I study of continuous infusion 5-fluorouracil plus calcium leucovorin in combination with N-(phosphonacetyl)-L-aspartate in metastatic gastrointestinal adenocarcinoma.
    Grem JL, McAtee N, Steinberg SM, Hamilton JM, Murphy RF, Drake J, Chisena T, Balis F, Cysyk R, Arbuck SG.
    Cancer Res; 1993 Oct 15; 53(20):4828-36. PubMed ID: 8402669
    [Abstract] [Full Text] [Related]

  • 7. Flux through the de novo pyrimidine pathway in vivo. Effect of N-phosphonacetyl-L-aspartate, a potent inhibitor of aspartate transcarbamylase.
    Monks A, Anderson LW, Strong J, Cysyk RL.
    J Biol Chem; 1983 Nov 25; 258(22):13564-9. PubMed ID: 6417130
    [Abstract] [Full Text] [Related]

  • 8. Measurement of aspartate carbamoyltransferase activity by high performance liquid chromatography.
    Grem JL, Drake JC, Allegra CJ.
    Anticancer Drugs; 1993 Oct 25; 4(5):545-54. PubMed ID: 8292811
    [Abstract] [Full Text] [Related]

  • 9. Pharmacological disposition of N-(phosphonacetyl)-L-aspartate in humans.
    Loo TL, Friedman J, Moore EC, Valdivieso M, Marti JR, Stewart D.
    Cancer Res; 1980 Jan 25; 40(1):86-90. PubMed ID: 7349907
    [Abstract] [Full Text] [Related]

  • 10. Binding of radiolabeled N-(phosphonacetyl)-L-aspartate to aspartate transcarbamylase from Ehrlich ascites tumor cells.
    White JC, Hines LH.
    Biochem Pharmacol; 1984 Nov 15; 33(22):3645-8. PubMed ID: 6508821
    [Abstract] [Full Text] [Related]

  • 11. An overview of the clinical pharmacology of N-phosphonacetyl-L-aspartate (PALA), a new antimetabolite.
    Erlichman C.
    Recent Results Cancer Res; 1980 Nov 15; 74():65-71. PubMed ID: 7444150
    [Abstract] [Full Text] [Related]

  • 12. Peripheral leukocytes as indicators of the enzymatic effects of N-(phosphonacetyl)-L-aspartic acid (PALA) on human L-aspartate transcarbamoylase (ATCase) activity.
    Kensler TW, Erlichman C, Jayaram HN, Tyagi AK, Ardalan B, Cooney DA.
    Cancer Treat Rep; 1980 Nov 15; 64(8-9):967-73. PubMed ID: 7448831
    [Abstract] [Full Text] [Related]

  • 13. Mechanism of synergy between N-phosphonacetyl-L-aspartate and dipyridamole in a human ovarian carcinoma cell line.
    Chan TC, Howell SB.
    Cancer Res; 1985 Aug 15; 45(8):3598-604. PubMed ID: 4016741
    [Abstract] [Full Text] [Related]

  • 14. Dose-dependent inhibition of aspartate carbamoyltransferase in peripheral blood mononuclear cells in patients receiving N-(phosphonacetyl)-L-aspartate.
    Grem JL, McAtee N, Drake JC, Steinberg S, Allegra CJ.
    Adv Exp Med Biol; 1993 Aug 15; 339():119-23. PubMed ID: 8178710
    [Abstract] [Full Text] [Related]

  • 15. Collateral sensitivity to N-(phosphonacetyl)-L-aspartic acid in a line of P388 leukemia cells selected for resistance to L-(alpha S, 5S)-alpha-amino-3- chloro-4,5-dihydro-5-isoxazoleacetic acid (acivicin).
    Ardalan B, Jayaram HN, Johnson RK.
    Cancer Res; 1983 Apr 15; 43(4):1598-601. PubMed ID: 6831405
    [Abstract] [Full Text] [Related]

  • 16. Pharmacological and biochemical interactions of N-(phosphonacetyl)-L-aspartate and 5-fluorouracil in beagles.
    Miller AA, Moore EC, Hurlbert RB, Benvenuto JA, Loo TL.
    Cancer Res; 1983 Jun 15; 43(6):2565-70. PubMed ID: 6189583
    [Abstract] [Full Text] [Related]

  • 17. Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid.
    Kensler TW, Mutter G, Hankerson JG, Reck LJ, Harley C, Han N, Ardalan B, Cysyk RL, Johnson RK, Jayaram HN, Cooney DA.
    Cancer Res; 1981 Mar 15; 41(3):894-904. PubMed ID: 7459875
    [Abstract] [Full Text] [Related]

  • 18. Mechanisms of sensitivity or resistance of murine tumors to N-(phosphonacetyl)-L-aspartate (PALA).
    Jayaram HN, Cooney DA, Vistica DT, Kariya S, Johnson RK.
    Cancer Treat Rep; 1979 Aug 15; 63(8):1291-302. PubMed ID: 476706
    [Abstract] [Full Text] [Related]

  • 19. Effects of acivicin and PALA, singly and in combination, on de novo pyrimidine biosynthesis.
    Kensler TW, Jayaram HN, Cooney DA.
    Adv Enzyme Regul; 1982 Aug 15; 20():57-73. PubMed ID: 7113804
    [Abstract] [Full Text] [Related]

  • 20. Enzymatic assay for the antitumor agent-N-(phosphonacetyl)-L-aspartic acid (PALA).
    Friedman J, Moore EC, Hall SW, Loo TL.
    Cancer Treat Rep; 1979 Jan 15; 63(1):85-8. PubMed ID: 421235
    [Abstract] [Full Text] [Related]

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