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Journal Abstract Search


205 related items for PubMed ID: 7189661

  • 1. The effect of compactin, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase activity, on cholesterogenesis and serum cholesterol levels in rats and chicks.
    Fears R, Richards DH, Ferres H.
    Atherosclerosis; 1980 Apr; 35(4):439-49. PubMed ID: 7189661
    [Abstract] [Full Text] [Related]

  • 2. Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats.
    Maxwell RE, Nawrocki JW, Uhlendorf PD.
    Atherosclerosis; 1983 Sep; 48(3):195-203. PubMed ID: 6579963
    [Abstract] [Full Text] [Related]

  • 3. The effect of cholestyramine and Mevinolin on the diurnal cycle of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase.
    Tanaka RD, Edwards PA, Lan SF, Knöppel EM, Fogelman AM.
    J Lipid Res; 1982 Sep; 23(7):1026-31. PubMed ID: 6923909
    [Abstract] [Full Text] [Related]

  • 4. Reduction of serum cholesterol in heterozygous patients with familial hypercholesterolemia. Additive effects of compactin and cholestyramine.
    Mabuchi H, Sakai T, Sakai Y, Yoshimura A, Watanabe A, Wakasugi T, Koizumi J, Takeda R.
    N Engl J Med; 1983 Mar 17; 308(11):609-13. PubMed ID: 6828091
    [Abstract] [Full Text] [Related]

  • 5. Effects of compactin, mevalonate and low-density lipoprotein on 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and low-density-lipoprotein-receptor activity in the human hepatoma cell line Hep G2.
    Cohen LH, Griffioen M, Havekes L, Schouten D, van Hinsbergh V, Kempen HJ.
    Biochem J; 1984 Aug 15; 222(1):35-9. PubMed ID: 6089762
    [Abstract] [Full Text] [Related]

  • 6. Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase.
    Endo A.
    J Med Chem; 1985 Apr 15; 28(4):401-5. PubMed ID: 3981532
    [No Abstract] [Full Text] [Related]

  • 7. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in human hepatoma cell line Hep G2. Effects of inhibitors of cholesterol synthesis on enzyme activity.
    Boogaard A, Griffioen M, Cohen LH.
    Biochem J; 1987 Jan 15; 241(2):345-51. PubMed ID: 3036060
    [Abstract] [Full Text] [Related]

  • 8. Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.
    Alberts AW, Chen J, Kuron G, Hunt V, Huff J, Hoffman C, Rothrock J, Lopez M, Joshua H, Harris E, Patchett A, Monaghan R, Currie S, Stapley E, Albers-Schonberg G, Hensens O, Hirshfield J, Hoogsteen K, Liesch J, Springer J.
    Proc Natl Acad Sci U S A; 1980 Jul 15; 77(7):3957-61. PubMed ID: 6933445
    [Abstract] [Full Text] [Related]

  • 9. New developments in lipid-lowering therapy: the role of inhibitors of hydroxymethylglutaryl-coenzyme A reductase.
    Tobert JA.
    Circulation; 1987 Sep 15; 76(3):534-8. PubMed ID: 3113763
    [Abstract] [Full Text] [Related]

  • 10. The role of substrate supply in the regulation of cholesterol biosynthesis in rat hepatocytes.
    Pullinger CR, Gibbons GF.
    Biochem J; 1983 Mar 15; 210(3):625-32. PubMed ID: 6870798
    [Abstract] [Full Text] [Related]

  • 11. Some effects of chitosan on liver function in the rat.
    LeHoux JG, Grondin F.
    Endocrinology; 1993 Mar 15; 132(3):1078-84. PubMed ID: 7679967
    [Abstract] [Full Text] [Related]

  • 12. CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species.
    Tsujita Y, Kuroda M, Shimada Y, Tanzawa K, Arai M, Kaneko I, Tanaka M, Masuda H, Tarumi C, Watanabe Y.
    Biochim Biophys Acta; 1986 Jun 11; 877(1):50-60. PubMed ID: 3636158
    [Abstract] [Full Text] [Related]

  • 13. Regulation of 3-hydroxy-3-methylglutaryl-CoA reductase by endogenous sterol synthesis in cultured intestinal mucosa.
    Stange EF, Preclik G, Schneider A, Alavi M, Ditschuneit H.
    Biochim Biophys Acta; 1981 Mar 23; 663(3):613-20. PubMed ID: 7225401
    [Abstract] [Full Text] [Related]

  • 14. Regulation of HMG-CoA reductase, apoprotein-B and LDL receptor gene expression by the hypocholesterolemic drugs simvastatin and ciprofibrate in Hep G2, human and rat hepatocytes.
    Qin W, Infante J, Wang SR, Infante R.
    Biochim Biophys Acta; 1992 Jul 09; 1127(1):57-66. PubMed ID: 1627634
    [Abstract] [Full Text] [Related]

  • 15. Effects of compactin on the levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase in compactin-resistant C100 and wild-type cells.
    Hardeman EC, Endo A, Simoni RD.
    Arch Biochem Biophys; 1984 Aug 01; 232(2):549-61. PubMed ID: 6380409
    [Abstract] [Full Text] [Related]

  • 16.
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    [No Abstract] [Full Text] [Related]

  • 17. Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
    Koga T, Shimada Y, Kuroda M, Tsujita Y, Hasegawa K, Yamazaki M.
    Biochim Biophys Acta; 1990 Jul 16; 1045(2):115-20. PubMed ID: 2116173
    [Abstract] [Full Text] [Related]

  • 18. Compactin inhibits cholesterol synthesis in lymphocytes and intestinal mucosa from patients with familial hypercholesterolaemia.
    Betteridge DJ, Krone W, Reckless JP, Galton DJ.
    Lancet; 1990 Jul 16; 2(8104-5):1342-3. PubMed ID: 82843
    [Abstract] [Full Text] [Related]

  • 19. Effects of an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase on serum lipoproteins and ubiquinone-10-levels in patients with familial hypercholesterolemia.
    Mabuchi H, Haba T, Tatami R, Miyamoto S, Sakai Y, Wakasugi T, Watanabe A, Koizumi J, Takeda R.
    N Engl J Med; 1981 Aug 27; 305(9):478-82. PubMed ID: 7254297
    [Abstract] [Full Text] [Related]

  • 20. Stimulation of the proliferation of the Madin-Darby canine kidney (MDCK) epithelial cell line by high-density lipoproteins and their induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.
    Gospodarowicz D, Cohen DC, Massoglia SL.
    J Cell Physiol; 1983 Oct 27; 117(1):76-90. PubMed ID: 6352714
    [Abstract] [Full Text] [Related]


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