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Journal Abstract Search
129 related items for PubMed ID: 7241512
1. Inhibition of bovine and rat liver dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(4-substituted-phenyl)-s-triazines. Hansch C, Dietrich SW, Fukunaga JY. J Med Chem; 1981 May; 24(5):544-9. PubMed ID: 7241512 [No Abstract] [Full Text] [Related]
2. A comparison of the inhibition of bovine and murine leukemia dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-X-phenyl)-s-triazines. Guo ZR, Dietrich SW, Hansch C, Dolnick BJ, Bertino JR. Mol Pharmacol; 1981 Nov; 20(3):649-56. PubMed ID: 7329407 [No Abstract] [Full Text] [Related]
3. Inhibition of dihydrofolate reductase. 3. 4.6-Diamino-1,2-dihydro-2,2-dimethyl-1-(2-substituted-phenyl)-s-triazine inhibition of bovine liver and mouse tumor enzymes. Kim KH, Dietrich SW, Hansch C, Dolnick BJ, Bertino JR. J Med Chem; 1980 Nov; 23(11):1248-51. PubMed ID: 7452676 [Abstract] [Full Text] [Related]
4. Inhibition of human dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(substituted-phenyl)-s-triazine s. A quantitative structure-activity relationship analysis. Hathaway BA, Guo ZR, Hansch C, Delcamp TJ, Susten SS, Freisheim JH. J Med Chem; 1984 Feb; 27(2):144-9. PubMed ID: 6694162 [Abstract] [Full Text] [Related]
9. Irreversible enzyme inhibitors. CLXXVI. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine by ether bridging to a terminal sulfonyl fluoride. Baker BR, Ashton WT. J Med Chem; 1970 Nov 17; 13(6):1149-54. PubMed ID: 5479855 [No Abstract] [Full Text] [Related]
10. Irreversible enzyme inhibitors. 197. Water-soluble reversible inhibitors of dihydrofolate reductase with potent antitumor activity derived from 4, 6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine. Baker BR, Ashton WT. J Med Chem; 1973 Mar 17; 16(3):209-14. PubMed ID: 4733101 [No Abstract] [Full Text] [Related]
11. Irreversible enzyme inhibitors. CLXXIX. Active-site-directed irreversible enzyme inhibitors of dihydrofolate reductase from 1-(3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with oxyamide bridges to a terminal sulfonyl fluoride. Baker BR, Ashton WT. J Med Chem; 1970 Nov 17; 13(6):1165-70. PubMed ID: 5479858 [No Abstract] [Full Text] [Related]
12. Crystallography, quantitative structure-activity relationships, and molecular graphics in a comparative analysis of the inhibition of dihydrofolate reductase from chicken liver and Lactobacillus casei by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(substituted-phenyl)-s-triazine s. Hansch C, Hathaway BA, Guo ZR, Selassie CD, Dietrich SW, Blaney JM, Langridge R, Volz KW, Kaufman BT. J Med Chem; 1984 Feb 17; 27(2):129-43. PubMed ID: 6420569 [Abstract] [Full Text] [Related]
13. Comparison of the inhibition of methotrexate-sensitive and -resistant Lactobacillus casei cell cultures with purified Lactobacillus casei dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-substituted-phenyl)-s-triazines. Use of quantitative structure-activity relationships in making inferences about the mechanism of resistance and the structure of the enzyme is situ compared with the enzyme in vitro. Coats EA, Genther CS, Dietrich SW, Guo ZR, Hansch C. J Med Chem; 1981 Dec 17; 24(12):1422-9. PubMed ID: 6796688 [Abstract] [Full Text] [Related]
15. Comparison of triazines as inhibitors of L1210 dihydrofolate reductase and of L1210 cells sensitive and resistant to methotrexate. Selassie CD, Strong CD, Hansch C, Delcamp TJ, Freisheim JH, Khwaja TA. Cancer Res; 1986 Feb 17; 46(2):744-56. PubMed ID: 3940640 [Abstract] [Full Text] [Related]
17. Dihydrofolate reductase inhibition by 2,4-diaminotriazines: A structure-activity study. Dietrich SW, Smith RN, Fukunaga JY, Olney M, Hansch C. Arch Biochem Biophys; 1979 May 17; 194(2):600-11. PubMed ID: 443823 [No Abstract] [Full Text] [Related]