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Journal Abstract Search


129 related items for PubMed ID: 7241512

  • 21. Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase.
    Srinivasan B, Tonddast-Navaei S, Skolnick J.
    Eur J Med Chem; 2015 Oct 20; 103():600-14. PubMed ID: 26414808
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  • 22. A general QSAR for dihydrofolate reductase inhibition by 2,4-diaminotriazines based upon molecular shape analysis.
    Hopfinger AJ.
    Arch Biochem Biophys; 1981 Jan 20; 206(1):153-63. PubMed ID: 7212714
    [No Abstract] [Full Text] [Related]

  • 23. Quantitative structure-activity relationships by neural networks and inductive logic programming. II. The inhibition of dihydrofolate reductase by triazines.
    Hirst JD, King RD, Sternberg MJ.
    J Comput Aided Mol Des; 1994 Aug 20; 8(4):421-32. PubMed ID: 7815093
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  • 24. Pharmacokinetics of Aryldihydro-s-triazines with antifolate activity II: Blood levels and their relevance to antineoplastic activity in rats.
    Upton RA, Ashley JJ, Ryan AJ.
    J Pharm Sci; 1978 Mar 20; 67(3):310-4. PubMed ID: 641713
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  • 25. Irreversible enzyme inhibitors. 173. Cure of Walker 256 ascites by reversible and irreversible inhibitors of dihydrofolic reductase derived from 1-(substituted-phenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine.
    Baker BR, Vermeulen NM, Ashton WT, Ryan AJ.
    J Med Chem; 1970 Nov 20; 13(6):1130-40. PubMed ID: 5479852
    [No Abstract] [Full Text] [Related]

  • 26. Triazines and related products. IX. Potential irreversible dihydrofolate reductase inhibitors: 2,4-diamino-S-triazines with a masked covalent labelling group.
    Mackenzie SM, Stevens MF.
    J Chem Soc Perkin 1; 1972 Nov 20; 3():295-8. PubMed ID: 5065592
    [No Abstract] [Full Text] [Related]

  • 27. Irreversible enzyme inhibitors. CLXXIV. Metabolism of 4-(p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)hydrocinnamido)-o-toluenesulfonyl fluoride (NSC-113423), an active-site-directed irreversible inhibitor of dihydrofolic reductase.
    Ryan AJ, Vermeulen NM, Baker BR.
    J Med Chem; 1970 Nov 20; 13(6):1140-2. PubMed ID: 5479853
    [No Abstract] [Full Text] [Related]

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  • 29. Quantitative structure-activity relationship of triazine-antifolate inhibition of Leishmania dihydrofolate reductase and cell growth.
    Booth RG, Selassie CD, Hansch C, Santi DV.
    J Med Chem; 1987 Jul 20; 30(7):1218-24. PubMed ID: 3599028
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  • 35. A comparison of the inhibitory action of 5-(substituted-benzyl)-2,4-diaminopyrimidines on dihydrofolate reductase from chicken liver with that from bovine liver.
    Li R, Hansch C, Kaufman BT.
    J Med Chem; 1982 Apr 20; 25(4):435-40. PubMed ID: 7069722
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  • 37. Irreversible enzyme inhibitors. CLIX. Effect of substitution on transport and isozyme specificity of p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)-o-chlorophenoxyacetamido-benzenesulfonyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase.
    Baker BR, Ashton WT.
    J Med Chem; 1969 Sep 20; 12(5):894-7. PubMed ID: 5812207
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