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129 related items for PubMed ID: 7241512
21. Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase. Srinivasan B, Tonddast-Navaei S, Skolnick J. Eur J Med Chem; 2015 Oct 20; 103():600-14. PubMed ID: 26414808 [Abstract] [Full Text] [Related]
22. A general QSAR for dihydrofolate reductase inhibition by 2,4-diaminotriazines based upon molecular shape analysis. Hopfinger AJ. Arch Biochem Biophys; 1981 Jan 20; 206(1):153-63. PubMed ID: 7212714 [No Abstract] [Full Text] [Related]
23. Quantitative structure-activity relationships by neural networks and inductive logic programming. II. The inhibition of dihydrofolate reductase by triazines. Hirst JD, King RD, Sternberg MJ. J Comput Aided Mol Des; 1994 Aug 20; 8(4):421-32. PubMed ID: 7815093 [Abstract] [Full Text] [Related]
24. Pharmacokinetics of Aryldihydro-s-triazines with antifolate activity II: Blood levels and their relevance to antineoplastic activity in rats. Upton RA, Ashley JJ, Ryan AJ. J Pharm Sci; 1978 Mar 20; 67(3):310-4. PubMed ID: 641713 [Abstract] [Full Text] [Related]
25. Irreversible enzyme inhibitors. 173. Cure of Walker 256 ascites by reversible and irreversible inhibitors of dihydrofolic reductase derived from 1-(substituted-phenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine. Baker BR, Vermeulen NM, Ashton WT, Ryan AJ. J Med Chem; 1970 Nov 20; 13(6):1130-40. PubMed ID: 5479852 [No Abstract] [Full Text] [Related]
26. Triazines and related products. IX. Potential irreversible dihydrofolate reductase inhibitors: 2,4-diamino-S-triazines with a masked covalent labelling group. Mackenzie SM, Stevens MF. J Chem Soc Perkin 1; 1972 Nov 20; 3():295-8. PubMed ID: 5065592 [No Abstract] [Full Text] [Related]
27. Irreversible enzyme inhibitors. CLXXIV. Metabolism of 4-(p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)hydrocinnamido)-o-toluenesulfonyl fluoride (NSC-113423), an active-site-directed irreversible inhibitor of dihydrofolic reductase. Ryan AJ, Vermeulen NM, Baker BR. J Med Chem; 1970 Nov 20; 13(6):1140-2. PubMed ID: 5479853 [No Abstract] [Full Text] [Related]
35. A comparison of the inhibitory action of 5-(substituted-benzyl)-2,4-diaminopyrimidines on dihydrofolate reductase from chicken liver with that from bovine liver. Li R, Hansch C, Kaufman BT. J Med Chem; 1982 Apr 20; 25(4):435-40. PubMed ID: 7069722 [Abstract] [Full Text] [Related]