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2. An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia. McLain GE, Sipes IG, Brown BR. Anesthesiology; 1979 Oct; 51(4):321-6. PubMed ID: 484893 [Abstract] [Full Text] [Related]
8. Halothane hepatotoxicity: relation between metabolic activation, hypoxia, covalent binding, lipid peroxidation and liver cell damage. de Groot H, Noll T. Hepatology; 1983 Dec 15; 3(4):601-6. PubMed ID: 6345332 [No Abstract] [Full Text] [Related]
9. Effect of oxygen concentration on the reaction of halothane with cytochrome P450 in liver microsomes and isolated perfused rat liver. Nastainczyk W, Ullrich V. Biochem Pharmacol; 1978 Feb 15; 27(4):387-92. PubMed ID: 629799 [No Abstract] [Full Text] [Related]
10. Anaerobic dehalogenation of halothane by reconstituted liver microsomal cytochrome P-450 enzyme system. Fujii K, Miki N, Sugiyama T, Morio M, Yamano T, Miyake Y. Biochem Biophys Res Commun; 1981 Sep 16; 102(1):507-12. PubMed ID: 6796089 [No Abstract] [Full Text] [Related]
11. Characterization of halothane oxidation by hepatic microsomes and purified cytochromes P-450 using a gas chromatographic mass spectrometric assay. Gruenke LD, Konopka K, Koop DR, Waskell LA. J Pharmacol Exp Ther; 1988 Aug 16; 246(2):454-9. PubMed ID: 3404442 [Abstract] [Full Text] [Related]
13. Effects of phenobarbital pretreatment on the response of rat liver to halothane administration. Stenger RJ, Johnson EA. Proc Soc Exp Biol Med; 1972 Sep 16; 140(4):1319-24. PubMed ID: 5057597 [No Abstract] [Full Text] [Related]
14. Comparison of covalent binding from halothane metabolism in hepatic microsomes from phenobarbital-induced and hyperthyroid rats. Smith AC, Roberts SM, James RC, Berman LM, Harbison RD. Xenobiotica; 1988 Aug 16; 18(8):991-1001. PubMed ID: 3188577 [Abstract] [Full Text] [Related]
15. Factors influencing halothane hepatotoxicity in the rat hypoxic model. Jee RC, Sipes IG, Gandolfi AJ, Brown BR. Toxicol Appl Pharmacol; 1980 Feb 16; 52(2):267-77. PubMed ID: 6767300 [No Abstract] [Full Text] [Related]
16. Reductive metabolism of halothane by cytochrome P450 isoforms in rats and humans. Chow T, Imaoka S, Hiroi T, Funae Y. Res Commun Mol Pathol Pharmacol; 1996 Sep 16; 93(3):363-74. PubMed ID: 8896047 [Abstract] [Full Text] [Related]
17. Reductive metabolism of halothane by human and rabbit cytochrome P-450. Binding of 1-chloro-2,2,2-trifluoroethyl radical to phospholipids. Trudell JR, Bösterling B, Trevor AJ. Mol Pharmacol; 1982 May 16; 21(3):710-7. PubMed ID: 7110119 [No Abstract] [Full Text] [Related]
18. The in vitro metabolism of halothane (2-bromo-2-chloro-1,1,1-trifluoroethane) by hepatic microsomal cytochrome P-450. Karashima D, Hirokata Y, Shigematsu A, Furukawa T. J Pharmacol Exp Ther; 1977 Nov 16; 203(2):409-16. PubMed ID: 909072 [Abstract] [Full Text] [Related]
19. Halothane hepatotoxicity and reductive metabolism of halothane in acute experimental liver injury in rats. Nomura F, Hatano H, Iida S, Ohnishi K. Anesth Analg; 1988 May 16; 67(5):448-52. PubMed ID: 3364763 [Abstract] [Full Text] [Related]