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279 related items for PubMed ID: 7476909

  • 1. Hypophosphorylation of topoisomerase II in etoposide (VP-16)-resistant human leukemia K562 cells associated with reduced levels of beta II protein kinase C.
    Ritke MK, Murray NR, Allan WP, Fields AP, Yalowich JC.
    Mol Pharmacol; 1995 Nov; 48(5):798-805. PubMed ID: 7476909
    [Abstract] [Full Text] [Related]

  • 2. Reduced phosphorylation of topoisomerase II in etoposide-resistant human leukemia K562 cells.
    Ritke MK, Allan WP, Fattman C, Gunduz NN, Yalowich JC.
    Mol Pharmacol; 1994 Jul; 46(1):58-66. PubMed ID: 8058057
    [Abstract] [Full Text] [Related]

  • 3. Resistance to etoposide in human leukemia HL-60 cells: reduction in drug-induced DNA cleavage associated with hypophosphorylation of topoisomerase II phosphopeptides.
    Ganapathi R, Constantinou A, Kamath N, Dubyak G, Grabowski D, Krivacic K.
    Mol Pharmacol; 1996 Aug; 50(2):243-8. PubMed ID: 8700130
    [Abstract] [Full Text] [Related]

  • 4. Multidrug resistance due to impaired DNA cleavage in a VP-16-resistant human leukemia cell line.
    Fukushima T, Takemura H, Yamashita T, Ishisaka T, Inai K, Imamura S, Urasaki Y, Ueda T.
    Anticancer Res; 1999 Aug; 19(6B):5111-5. PubMed ID: 10697518
    [Abstract] [Full Text] [Related]

  • 5. Increased phosphorylation of DNA topoisomerase II in etoposide-resistant mutants of human cancer KB cells.
    Takano H, Kohno K, Ono M, Uchida Y, Kuwano M.
    Cancer Res; 1991 Aug 01; 51(15):3951-7. PubMed ID: 1649696
    [Abstract] [Full Text] [Related]

  • 6. Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance.
    Schneider E, Horton JK, Yang CH, Nakagawa M, Cowan KH.
    Cancer Res; 1994 Jan 01; 54(1):152-8. PubMed ID: 7903202
    [Abstract] [Full Text] [Related]

  • 7. Chinese hamster ovary cells resistant to the topoisomerase II catalytic inhibitor ICRF-159: a Tyr49Phe mutation confers high-level resistance to bisdioxopiperazines.
    Sehested M, Wessel I, Jensen LH, Holm B, Oliveri RS, Kenwrick S, Creighton AM, Nitiss JL, Jensen PB.
    Cancer Res; 1998 Apr 01; 58(7):1460-8. PubMed ID: 9537249
    [Abstract] [Full Text] [Related]

  • 8. Differential induction of etoposide-mediated apoptosis in human leukemia HL-60 and K562 cells.
    Ritke MK, Rusnak JM, Lazo JS, Allan WP, Dive C, Heer S, Yalowich JC.
    Mol Pharmacol; 1994 Oct 01; 46(4):605-11. PubMed ID: 7969039
    [Abstract] [Full Text] [Related]

  • 9. Cellular adaptation to drug exposure: evolution of the drug-resistant phenotype.
    Matsumoto Y, Takano H, Fojo T.
    Cancer Res; 1997 Nov 15; 57(22):5086-92. PubMed ID: 9371507
    [Abstract] [Full Text] [Related]

  • 10. Effect of phorbol ester treatment on drug-induced, topoisomerase II-mediated DNA cleavage in human leukemia cells.
    Zwelling LA, Chan D, Hinds M, Mayes J, Silberman LE, Blick M.
    Cancer Res; 1988 Dec 01; 48(23):6625-33. PubMed ID: 2846155
    [Abstract] [Full Text] [Related]

  • 11. Characterization of an unusual mutant of human melanoma cells resistant to anticancer drugs that inhibit topoisomerase II.
    Campain JA, Padmanabhan R, Hwang J, Gottesman MM, Pastan I.
    J Cell Physiol; 1993 May 01; 155(2):414-25. PubMed ID: 8097746
    [Abstract] [Full Text] [Related]

  • 12. Transfection of a human topoisomerase II alpha gene into etoposide-resistant human breast tumor cells sensitizes the cells to etoposide.
    Asano T, An T, Zwelling LA, Takano H, Fojo AT, Kleinerman ES.
    Oncol Res; 1996 May 01; 8(3):101-10. PubMed ID: 8823806
    [Abstract] [Full Text] [Related]

  • 13. Reduced expression of DNA topoisomerase II confers resistance to etoposide (VP-16) in small cell lung cancer cell lines established from a refractory tumor of a patient and by in vitro selection.
    Andoh T, Nishizawa M, Hida T, Ariyoshi Y, Takahashi T, Ueda R.
    Oncol Res; 1996 May 01; 8(6):229-38. PubMed ID: 8895198
    [Abstract] [Full Text] [Related]

  • 14. Altered topoisomerase II alpha in a drug-resistant small cell lung cancer cell line selected in VP-16.
    Mirski SE, Evans CD, Almquist KC, Slovak ML, Cole SP.
    Cancer Res; 1993 Oct 15; 53(20):4866-73. PubMed ID: 8104687
    [Abstract] [Full Text] [Related]

  • 15. Decreased DNA topoisomerase II alpha expression and cold-sensitive growth in a mouse mammary cancer cell line resistant to etoposide and doxorubicin.
    Kawanami K, Nakamura T, Ono M, Kusano T, Okada K, Kikuchi A, Adachi N, Kohno K, Higashi K, Kuwano M.
    Oncol Res; 1996 Oct 15; 8(5):197-206. PubMed ID: 8884812
    [Abstract] [Full Text] [Related]

  • 16. DNA topoisomerase: the mechanism of resistance to DNA topoisomerase II inhibitor VP-16.
    Hong JH.
    Hiroshima J Med Sci; 1989 Dec 15; 38(4):197-207. PubMed ID: 2561562
    [Abstract] [Full Text] [Related]

  • 17. Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells.
    Ritke MK, Roberts D, Allan WP, Raymond J, Bergoltz VV, Yalowich JC.
    Br J Cancer; 1994 Apr 15; 69(4):687-97. PubMed ID: 8142256
    [Abstract] [Full Text] [Related]

  • 18. Development and characterization of a WEHI-3B D+ monomyelocytic leukemia cell line resistant to novobiocin and cross-resistant to other topoisomerase II-targeted drugs.
    Rappa G, Lorico A, Sartorelli AC.
    Cancer Res; 1992 May 15; 52(10):2782-90. PubMed ID: 1316227
    [Abstract] [Full Text] [Related]

  • 19. Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene.
    Lorico A, Rappa G, Srimatkandada S, Catapano CV, Fernandes DJ, Germino JF, Sartorelli AC.
    Cancer Res; 1995 Oct 01; 55(19):4352-60. PubMed ID: 7671247
    [Abstract] [Full Text] [Related]

  • 20. Reversal of etoposide resistance in non-P-glycoprotein expressing multidrug resistant tumor cell lines by novobiocin.
    Rappa G, Lorico A, Sartorelli AC.
    Cancer Res; 1993 Nov 15; 53(22):5487-93. PubMed ID: 8106148
    [Abstract] [Full Text] [Related]

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