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Journal Abstract Search


162 related items for PubMed ID: 7482544

  • 1. Conjugation of acrylonitrile and 2-cyanoethylene oxide with hepatic glutathione.
    Kedderis GL, Batra R, Turner MJ.
    Toxicol Appl Pharmacol; 1995 Nov; 135(1):9-17. PubMed ID: 7482544
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  • 2. A physiologically based dosimetry description of acrylonitrile and cyanoethylene oxide in the rat.
    Gargas ML, Andersen ME, Teo SK, Batra R, Fennell TR, Kedderis GL.
    Toxicol Appl Pharmacol; 1995 Oct; 134(2):185-94. PubMed ID: 7570594
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  • 3. Dose-dependent urinary excretion of acrylonitrile metabolites by rats and mice.
    Kedderis GL, Sumner SC, Held SD, Batra R, Turner MJ, Roberts AE, Fennell TR.
    Toxicol Appl Pharmacol; 1993 Jun; 120(2):288-97. PubMed ID: 8511799
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  • 4. Species differences in the hydrolysis of 2-cyanoethylene oxide, the epoxide metabolite of acrylonitrile.
    Kedderis GL, Batra R.
    Carcinogenesis; 1993 Apr; 14(4):685-9. PubMed ID: 8472333
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  • 5. Species comparison of acrylonitrile epoxidation by microsomes from mice, rats and humans: relationship to epoxide concentrations in mouse and rat blood.
    Roberts AE, Kedderis GL, Turner MJ, Rickert DE, Swenberg JA.
    Carcinogenesis; 1991 Mar; 12(3):401-4. PubMed ID: 2009586
    [Abstract] [Full Text] [Related]

  • 6. Refinement and verification of the physiologically based dosimetry description for acrylonitrile in rats.
    Kedderis GL, Teo SK, Batra R, Held SD, Gargas ML.
    Toxicol Appl Pharmacol; 1996 Oct; 140(2):422-35. PubMed ID: 8887460
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  • 7. Epoxidation of acrylonitrile by rat and human cytochromes P450.
    Kedderis GL, Batra R, Koop DR.
    Chem Res Toxicol; 1993 Oct; 6(6):866-71. PubMed ID: 8117926
    [Abstract] [Full Text] [Related]

  • 8. Rodent tissue distribution of 2-cyanoethylene oxide, the epoxide metabolite of acrylonitrile.
    Kedderis GL, Batra R, Held SD, Loos MA, Teo SK.
    Toxicol Lett; 1993 Jul; 69(1):25-30. PubMed ID: 8356564
    [Abstract] [Full Text] [Related]

  • 9. Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile disposition in humans.
    Sweeney LM, Gargas ML, Strother DE, Kedderis GL.
    Toxicol Sci; 2003 Jan; 71(1):27-40. PubMed ID: 12520073
    [Abstract] [Full Text] [Related]

  • 10. Determination of tissue partition coefficients for volatile tissue-reactive chemicals: acrylonitrile and its metabolite 2-cyanoethylene oxide.
    Teo SK, Kedderis GL, Gargas ML.
    Toxicol Appl Pharmacol; 1994 Sep; 128(1):92-6. PubMed ID: 8079360
    [Abstract] [Full Text] [Related]

  • 11. Analysis of DNA Adducts and Mutagenic Potency and Specificity in Rats Exposed to Acrylonitrile.
    Walker VE, Fennell TR, Walker DM, Bauer MJ, Upton PB, Douglas GR, Swenberg JA.
    Chem Res Toxicol; 2020 Jul 20; 33(7):1609-1622. PubMed ID: 32529823
    [Abstract] [Full Text] [Related]

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  • 14. Glutathione conjugation of 1,2:3,4- diepoxybutane in human liver and rat and mouse liver and lung in vitro.
    Boogaard PJ, Sumner SC, Bond JA.
    Toxicol Appl Pharmacol; 1996 Feb 20; 136(2):307-16. PubMed ID: 8619238
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  • 16. Metabolic detoxification determines species differences in coumarin-induced hepatotoxicity.
    Vassallo JD, Hicks SM, Daston GP, Lehman-McKeeman LD.
    Toxicol Sci; 2004 Aug 20; 80(2):249-57. PubMed ID: 15141102
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  • 17. Conjugation of glutathione with a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, catalyzed by rat hepatic glutathione-S-transferases.
    Tang W, Borel AG, Abbott FS.
    Drug Metab Dispos; 1996 Apr 20; 24(4):436-46. PubMed ID: 8801059
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  • 19. Comparative metabolism of 1,2,3,3,3-pentafluoropropene in male and female mouse, rat, dog, and human liver microsomes and cytosol and male rat hepatocytes via oxidative dehalogenation and glutathione S-conjugation pathways.
    Han X, Szostek B, Yang CH, Cheatham SF, Mingoia RT, Nabb DL, Gannon SA, Himmelstein MW, Jepson GW.
    Drug Metab Dispos; 2011 Jul 20; 39(7):1288-93. PubMed ID: 21493824
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