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122 related items for PubMed ID: 7492781

  • 1. In vitro and in vivo antileukemic activity of B43-pokeweed antiviral protein against radiation-resistant human B-cell precursor leukemia cells.
    Waddick KG, Myers DE, Gunther R, Chelstrom LM, Chandan-Langlie M, Irvin JD, Tumer N, Uckun FM.
    Blood; 1995 Dec 01; 86(11):4228-33. PubMed ID: 7492781
    [Abstract] [Full Text] [Related]

  • 2. Effective immunochemotherapy of CALLA+C mu+ human pre-B acute lymphoblastic leukemia in mice with severe combined immunodeficiency using B43 (anti-CD19) pokeweed antiviral protein immunotoxin plus cyclophosphamide.
    Uckun FM, Chelstrom LM, Finnegan D, Tuel-Ahlgren L, Manivel C, Irvin JD, Myers DE, Gunther R.
    Blood; 1992 Jun 15; 79(12):3116-29. PubMed ID: 1375841
    [Abstract] [Full Text] [Related]

  • 3. In vivo efficacy of B43 (anti-CD19)-pokeweed antiviral protein immunotoxin against human pre-B cell acute lymphoblastic leukemia in mice with severe combined immunodeficiency.
    Uckun FM, Manivel C, Arthur D, Chelstrom LM, Finnegan D, Tuel-Ahlgren L, Irvin JD, Myers DE, Gunther R.
    Blood; 1992 May 01; 79(9):2201-14. PubMed ID: 1373967
    [Abstract] [Full Text] [Related]

  • 4. Effective immunochemotherapy of human t(4;11) leukemia in mice with severe combined immunodeficiency (SCID) using B43 (anti-CD19)-pokeweed antiviral protein immunotoxin plus cyclophosphamide.
    Jansen B, Kersey JH, Jaszcz WB, Gunther R, Nguyen DP, Chelstrom LM, Tuel-Ahlgren L, Uckun FM.
    Leukemia; 1993 Feb 01; 7(2):290-7. PubMed ID: 7678881
    [Abstract] [Full Text] [Related]

  • 5. Favorable pharmacodynamic features and superior anti-leukemic activity of B43 (anti-CD19) immunotoxins containing two pokeweed antiviral protein molecules covalently linked to each monoclonal antibody molecule.
    Myers DE, Yanishevski Y, Masson E, Irvin JD, Evans WE, Uckun FM.
    Leuk Lymphoma; 1995 Jun 01; 18(1-2):93-102. PubMed ID: 8580835
    [Abstract] [Full Text] [Related]

  • 6. Treatment of human B-cell precursor leukemia in SCID mice by using a combination of the anti-CD19 immunotoxin B43-PAP with the standard chemotherapeutic drugs vincristine, methylprednisolone, and L-asparaginase.
    Ek O, Gaynon P, Zeren T, Chelstrom LM, Myers DE, Uckun FM.
    Leuk Lymphoma; 1998 Sep 01; 31(1-2):143-9. PubMed ID: 9720724
    [Abstract] [Full Text] [Related]

  • 7. In vivo efficacy of B43 (anti-CD19)-pokeweed antiviral protein immunotoxin against BCL-1 murine B-cell leukemia.
    Uckun FM, Chelstrom LM, Irvin JD, Finnegan D, Gunther R, Young J, Kuebelbeck V, Myers DE, Houston LL.
    Blood; 1992 May 15; 79(10):2649-61. PubMed ID: 1375109
    [Abstract] [Full Text] [Related]

  • 8. Evaluation of temozolomide in a SCID mouse model of human B-cell precursor leukemia.
    Messinger Y, Reaman GH, Ek O, Uckun FM.
    Leuk Lymphoma; 1999 Apr 15; 33(3-4):289-93. PubMed ID: 10221508
    [Abstract] [Full Text] [Related]

  • 9. Biotherapy for xenografted human central nervous system leukemia in mice with severe combined immunodeficiency using B43 (anti-CD19)-pokeweed antiviral protein immunotoxin.
    Gunther R, Chelstrom LM, Tuel-Ahlgren L, Simon J, Myers DE, Uckun FM.
    Blood; 1995 May 01; 85(9):2537-45. PubMed ID: 7537120
    [Abstract] [Full Text] [Related]

  • 10. Use of a novel colony assay to evaluate the cytotoxicity of an immunotoxin containing pokeweed antiviral protein against blast progenitor cells freshly obtained from patients with common B-lineage acute lymphoblastic leukemia.
    Uckun FM, Gajl-Peczalska KJ, Kersey JH, Houston LL, Vallera DA.
    J Exp Med; 1986 Feb 01; 163(2):347-68. PubMed ID: 3511171
    [Abstract] [Full Text] [Related]

  • 11. Production of a pokeweed antiviral protein (PAP)-containing immunotoxin, B43-PAP, directed against the CD19 human B lineage lymphoid differentiation antigen in highly purified form for human clinical trials.
    Myers DE, Irvin JD, Smith RS, Kuebelbeck VM, Uckun FM.
    J Immunol Methods; 1991 Feb 15; 136(2):221-37. PubMed ID: 1705571
    [Abstract] [Full Text] [Related]

  • 12. Combined therapeutic efficacy of the thymidylate synthase inhibitor ZD1694 (Tomudex) and the immunotoxin B43(anti-CD19)-PAP in a SCID mouse model of human B-lineage acute lymphoblastic leukemia.
    Ek O, Reaman GH, Crankshaw DL, Chelstrom LM, Myers DE, Uckun FM.
    Leuk Lymphoma; 1998 Feb 15; 28(5-6):509-14. PubMed ID: 9613980
    [Abstract] [Full Text] [Related]

  • 13. An anti-CD72 immunotoxin against therapy-refractory B-lineage acute lymphoblastic leukemia.
    Myers DE, Uckun FM.
    Leuk Lymphoma; 1995 Jun 15; 18(1-2):119-22. PubMed ID: 8580813
    [Abstract] [Full Text] [Related]

  • 14. In vivo anti-leukemic efficacy of anti-CD7-pokeweed antiviral protein immunotoxin against human T-lineage acute lymphoblastic leukemia/lymphoma in mice with severe combined immunodeficiency.
    Gunther R, Chelstrom LM, Finnegan D, Tuel-Ahlgren L, Irvin JD, Myers DE, Uckun FM.
    Leukemia; 1993 Feb 15; 7(2):298-309. PubMed ID: 7678882
    [Abstract] [Full Text] [Related]

  • 15. Treatment of human B-cell precursor leukemia in SCID mice using a combination of the investigational biotherapeutic agent B43-PAP with cytosine arabinoside.
    Messinger Y, Yanishevski Y, Avramis VI, Ek O, Chelstrom LM, Gunther R, Myers DE, Irvin JD, Evans W, Uckun FM.
    Clin Cancer Res; 1996 Sep 15; 2(9):1533-42. PubMed ID: 9816330
    [Abstract] [Full Text] [Related]

  • 16. Effects of the intermolecular toxin-monoclonal antibody linkage on the in vivo stability, immunogenicity and anti-leukemic activity of B43 (anti-CD19) pokeweed antiviral protein immunotoxin.
    Uckun FM, Myers DE, Irvin JD, Kuebelbeck VM, Finnegan D, Chelstrom LM, Houston LL.
    Leuk Lymphoma; 1993 Apr 15; 9(6):459-76. PubMed ID: 7687916
    [Abstract] [Full Text] [Related]

  • 17. Toxicity profile of the investigational new biotherapeutic agent, B43 (anti-CD19)-pokeweed antiviral protein immunotoxin.
    Gunther R, Chelstrom LM, Wendorf HR, Schneider EA, Covalciuc K, Johnson B, Clementson D, Irvin JD, Myers DE, Uckun FM.
    Leuk Lymphoma; 1996 Jun 15; 22(1-2):61-70, follow.186, color plate II-V. PubMed ID: 8724529
    [Abstract] [Full Text] [Related]

  • 18. Pharmacokinetic features, immunogenicity, and toxicity of B43(anti-CD19)-pokeweed antiviral protein immunotoxin in cynomolgus monkeys.
    Uckun FM, Yanishevski Y, Tumer N, Waurzyniak B, Messinger Y, Chelstrom LM, Lisowski EA, Ek O, Zeren T, Wendorf H, Langlie MC, Irvin JD, Myers DE, Fuller GB, Evans W, Gunther R.
    Clin Cancer Res; 1997 Mar 15; 3(3):325-37. PubMed ID: 9815689
    [Abstract] [Full Text] [Related]

  • 19. Therapy of human B-cell lymphoma bearing SCID mice is more effective with anti-CD19- and anti-CD38-saporin immunotoxins used in combination than with either immunotoxin used alone.
    Flavell DJ, Boehm DA, Emery L, Noss A, Ramsay A, Flavell SU.
    Int J Cancer; 1995 Jul 28; 62(3):337-44. PubMed ID: 7543082
    [Abstract] [Full Text] [Related]

  • 20. Feasibility Study of a Novel Experimental Induction Protocol Combining B43-PAP (Anti-CD19) Immunotoxin With Standard Induction Chemotherapy in Children and Adolescents With Relapsed B-Lineage ALL: A Report From the Children's Oncology Group.
    Meany HJ, Seibel NL, Krailo M, Villaluna D, Chen Z, Gaynon P, Neglia JP, Park JR, Hutchinson R, Sato JK, Wells RJ, Woods WG, Reaman G.
    J Immunother; 2015 Sep 28; 38(7):299-305. PubMed ID: 26261894
    [Abstract] [Full Text] [Related]

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