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Journal Abstract Search


158 related items for PubMed ID: 7493555

  • 1. An improved HPLC assay for the assessment of liver slice metabolic viability using 7-ethoxycoumarin.
    Walsh JS, Patanella JE, Halm KA, Facchine KL.
    Drug Metab Dispos; 1995 Aug; 23(8):869-74. PubMed ID: 7493555
    [Abstract] [Full Text] [Related]

  • 2. [14C]7-ethoxycoumarin metabolism by precision-cut rat hepatic slices.
    Ball SE, Thiel VE, Tio CO, Lim HK, Kao J, Sisenwine SF, Scatina J.
    Drug Metab Dispos; 1996 Apr; 24(4):383-9. PubMed ID: 8801051
    [Abstract] [Full Text] [Related]

  • 3. [Biotransformation processes in fertile hen's eggs. 1. Metabolic transformation of 7-ethoxycoumarin].
    Clement B, Mladek C.
    Pharmazie; 1995 Mar; 50(3):207-10. PubMed ID: 7732052
    [Abstract] [Full Text] [Related]

  • 4. Liver slices in dynamic organ culture. II. An in vitro cellular technique for the study of integrated drug metabolism using human tissue.
    Barr J, Weir AJ, Brendel K, Sipes IG.
    Xenobiotica; 1991 Mar; 21(3):341-50. PubMed ID: 1862659
    [Abstract] [Full Text] [Related]

  • 5. Comparison of the metabolism of 7-ethoxycoumarin and coumarin in precision-cut rat liver and lung slices.
    Price RJ, Renwick AB, Beamand JA, Esclangon F, Wield PT, Walters DG, Lake BG.
    Food Chem Toxicol; 1995 Mar; 33(3):233-7. PubMed ID: 7896234
    [Abstract] [Full Text] [Related]

  • 6. Short-term maintenance of phase I and II metabolism in precision-cut liver slices in dynamic organ culture.
    Ekins S.
    Drug Metab Dispos; 1996 Mar; 24(3):364-6. PubMed ID: 8820429
    [Abstract] [Full Text] [Related]

  • 7. Metabolism of 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2 (1H)-one (L-696,229), an HIV-1 reverse transcriptase inhibitor, by rat liver slices and in humans.
    Balani SK, Kauffman LR, Arison BH, Olah TV, Goldman ME, Varga SL, O'Brien JA, Ramjit HG, Rooney CS, Hoffman JM.
    Drug Metab Dispos; 1994 Mar; 22(2):200-5. PubMed ID: 7516852
    [Abstract] [Full Text] [Related]

  • 8. Tissue slices revisited: evaluation and development of a short-term incubation for integrated drug metabolism.
    Thohan S, Zurich MC, Chung H, Weiner M, Kane AS, Rosen GM.
    Drug Metab Dispos; 2001 Oct; 29(10):1337-42. PubMed ID: 11560878
    [Abstract] [Full Text] [Related]

  • 9. Analysis of the glucuronidation of 7-hydroxycoumarin by HPLC.
    Killard AJ, O'Kennedy R, Bogan DP.
    J Pharm Biomed Anal; 1996 Aug; 14(11):1585-90. PubMed ID: 8877866
    [Abstract] [Full Text] [Related]

  • 10. In vivo clearance of ethoxycoumarin and its prediction from In vitro systems. Use Of drug depletion and metabolite formation methods in hepatic microsomes and isolated hepatocytes.
    Carlile DJ, Stevens AJ, Ashforth EI, Waghela D, Houston JB.
    Drug Metab Dispos; 1998 Mar; 26(3):216-21. PubMed ID: 9492383
    [Abstract] [Full Text] [Related]

  • 11. On-line HPLC analysis system for metabolism and inhibition studies in precision-cut liver slices.
    van Midwoud PM, Janssen J, Merema MT, de Graaf IA, Groothuis GM, Verpoorte E.
    Anal Chem; 2011 Jan 01; 83(1):84-91. PubMed ID: 21128611
    [Abstract] [Full Text] [Related]

  • 12. Determination of 7-hydroxycoumarin and its glucuronide and sulphate conjugates in liver slice incubates by capillary zone electrophoresis.
    Duffy CF, O'Kennedy R.
    J Pharm Biomed Anal; 1998 Sep 01; 17(8):1279-84. PubMed ID: 9800648
    [Abstract] [Full Text] [Related]

  • 13. Metabolism of coumarin and 7-ethoxycoumarin by rat, mouse, guinea pig, cynomolgus monkey and human precision-cut liver slices.
    Steensma A, Beamand JA, Walters DG, Price RJ, Lake BG.
    Xenobiotica; 1994 Sep 01; 24(9):893-907. PubMed ID: 7810171
    [Abstract] [Full Text] [Related]

  • 14. Induction of physical dependence by chronic alcohol treatment and enhancement of hepatic metabolism of 7-ethoxycoumarin and subsequent conjugation of its metabolite in perfused rat livers.
    Hong SS, Roh HK, Dong MS, Cha YN.
    Arch Int Pharmacodyn Ther; 1987 Feb 01; 285(2):249-62. PubMed ID: 3579427
    [Abstract] [Full Text] [Related]

  • 15. Simultaneous determination of coumarin, 7-hydroxycoumarin and 7-hydroxycoumarin glucuronide in human serum and plasma by high-performance liquid chromatography.
    Bogan DP, O'Kennedy R.
    J Chromatogr B Biomed Appl; 1996 Nov 15; 686(2):267-73. PubMed ID: 8971609
    [Abstract] [Full Text] [Related]

  • 16. Biosynthesis and chemical synthesis of carboxyl-linked glucuronide of lithocholic acid.
    Panfil I, Lehman PA, Zimniak P, Ernst B, Franz T, Lester R, Radominska A.
    Biochim Biophys Acta; 1992 Jun 22; 1126(2):221-8. PubMed ID: 1627626
    [Abstract] [Full Text] [Related]

  • 17. Liver slices in dynamic organ culture. I. An alternative in vitro technique for the study of rat hepatic drug metabolism.
    Barr J, Weir AJ, Brendel K, Sipes IG.
    Xenobiotica; 1991 Mar 22; 21(3):331-9. PubMed ID: 1862658
    [Abstract] [Full Text] [Related]

  • 18. HPLC-NMR with severe column overloading: fast-track metabolite identification in urine and bile samples from rat and dog treated with [14C]-ZD6126.
    Lenz EM, D'Souza RA, Jordan AC, King CD, Smith SM, Phillips PJ, McCormick AD, Roberts DW.
    J Pharm Biomed Anal; 2007 Feb 19; 43(3):1065-77. PubMed ID: 17030109
    [Abstract] [Full Text] [Related]

  • 19. Characterization by liquid chromatography-nuclear magnetic resonance spectroscopy and liquid chromatography-mass spectrometry of two coupled oxidative-conjugative metabolic pathways for 7-ethoxycoumarin in human liver microsomes treated with alamethicin.
    Fisher MB, Jackson D, Kaerner A, Wrighton SA, Borel AG.
    Drug Metab Dispos; 2002 Mar 19; 30(3):270-5. PubMed ID: 11854144
    [Abstract] [Full Text] [Related]

  • 20. Structural and functional integrity of precision-cut liver slices in xenobiotic metabolism: a comparison of the dynamic organ and multiwell plate culture procedures.
    Hashemi E, Dobrota M, Till C, Ioannides C.
    Xenobiotica; 1999 Jan 19; 29(1):11-25. PubMed ID: 10078837
    [Abstract] [Full Text] [Related]


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