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Journal Abstract Search

237 related items for PubMed ID: 7498454

  • 1. Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin.
    Stubbs MT, Huber R, Bode W.
    FEBS Lett; 1995 Nov 13; 375(1-2):103-7. PubMed ID: 7498454
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  • 2. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
    Katz BA, Elrod K, Luong C, Rice MJ, Mackman RL, Sprengeler PA, Spencer J, Hataye J, Janc J, Link J, Litvak J, Rai R, Rice K, Sideris S, Verner E, Young W.
    J Mol Biol; 2001 Apr 13; 307(5):1451-86. PubMed ID: 11292354
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  • 3. Reconstructing the binding site of factor Xa in trypsin reveals ligand-induced structural plasticity.
    Reyda S, Sohn C, Klebe G, Rall K, Ullmann D, Jakubke HD, Stubbs MT.
    J Mol Biol; 2003 Jan 31; 325(5):963-77. PubMed ID: 12527302
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  • 4. A novel factor Xa inhibitor: structure-activity relationships and selectivity between factor Xa and thrombin.
    Katakura S, Nagahara T, Hara T, Iwamoto M.
    Biochem Biophys Res Commun; 1993 Dec 15; 197(2):965-72. PubMed ID: 8267636
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  • 5. Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase.
    Renatus M, Bode W, Huber R, Stürzebecher J, Stubbs MT.
    J Med Chem; 1998 Dec 31; 41(27):5445-56. PubMed ID: 9876114
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  • 7. Understanding protein-ligand interactions: the price of protein flexibility.
    Rauh D, Klebe G, Stubbs MT.
    J Mol Biol; 2004 Jan 30; 335(5):1325-41. PubMed ID: 14729347
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  • 10. Similarity study of serine proteases inhibitors.
    Perekhodtsev GD.
    Mol Divers; 2006 Feb 30; 10(1):81-3. PubMed ID: 16404529
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  • 12. In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
    Costanzo MJ, Almond HR, Hecker LR, Schott MR, Yabut SC, Zhang HC, Andrade-Gordon P, Corcoran TW, Giardino EC, Kauffman JA, Lewis JM, de Garavilla L, Haertlein BJ, Maryanoff BE.
    J Med Chem; 2005 Mar 24; 48(6):1984-2008. PubMed ID: 15771442
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  • 13. Complementary DNA cloning and kinetic characterization of a novel intracellular serine proteinase inhibitor: mechanism of action with trypsin and factor Xa as model proteinases.
    Morgenstern KA, Sprecher C, Holth L, Foster D, Grant FJ, Ching A, Kisiel W.
    Biochemistry; 1994 Mar 22; 33(11):3432-41. PubMed ID: 8136380
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  • 14. Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system.
    Rester U, Bode W, Moser M, Parry MA, Huber R, Auerswald E.
    J Mol Biol; 1999 Oct 15; 293(1):93-106. PubMed ID: 10512718
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  • 15. Understanding binding selectivity toward trypsin and factor Xa: the role of aromatic interactions.
    Di Fenza A, Heine A, Koert U, Klebe G.
    ChemMedChem; 2007 Mar 15; 2(3):297-308. PubMed ID: 17191291
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  • 17. Comparison of the structures of the cyclotheonamide A complexes of human alpha-thrombin and bovine beta-trypsin.
    Ganesh V, Lee AY, Clardy J, Tulinsky A.
    Protein Sci; 1996 May 15; 5(5):825-35. PubMed ID: 8732754
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  • 18. Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study.
    Nardini M, Pesce A, Rizzi M, Casale E, Ferraccioli R, Balliano G, Milla P, Ascenzi P, Bolognesi M.
    J Mol Biol; 1996 May 24; 258(5):851-9. PubMed ID: 8637015
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  • 19. Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors.
    Katz BA, Elrod K, Verner E, Mackman RL, Luong C, Shrader WD, Sendzik M, Spencer JR, Sprengeler PA, Kolesnikov A, Tai VW, Hui HC, Breitenbucher JG, Allen D, Janc JW.
    J Mol Biol; 2003 May 23; 329(1):93-120. PubMed ID: 12742021
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  • 20. Comparative molecular modeling analysis of-5-amidinoindole and benzamidine binding to thrombin and trypsin: specific H-bond formation contributes to high 5-amidinoindole potency and selectivity for thrombin and factor Xa.
    Zhou Y, Johnson ME.
    J Mol Recognit; 1999 May 23; 12(4):235-41. PubMed ID: 10440994
    [Abstract] [Full Text] [Related]

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